Sarah Hewlett Sarah.Hewlett@uwe.ac.uk
Rheumatoid arthritis patients cannot accurately report signs of inflammatory activity
Hewlett, Sarah; Haynes, Julie; Shepstone, L; Kirwan, John R.
Authors
Julie Taylor Julie6.Taylor@uwe.ac.uk
Associate Lecturer - CHSS - HSW - UHSW0001
L Shepstone
John R. Kirwan
Abstract
If patients with rheumatoid arthritis (RA) could self-report symptoms in a manner which correlated with laboratory measures of inflammation this would be a valuable research or clinical tool. Developing such a tool means ensuring that the questions are understood and a variety of combinations of signs, symptoms and joints explored. Preliminary studies in two groups of 20
RA out-patients established an acceptable self-report questionnaire format by which patients could identify their joints. Fifty RA out-patients completed these self-report forms on four grades of each of four symptoms (pain, heat, stiffness, swelling) in each of 64 joints, as well as visual analogue scales (VAS) on overall pain and perceived disease activity. A clinical research assistant recorded the Thompson-Kirwan articular index (TKAI) and plasma viscosity (PV) was measured. The data were analysed in a variety of ways in an attempt to construct a self-report articular index (SRAI) which correlated with PV. The
strongest models were then tested in 11 in-patients undergoing a flare of their disease. No adequate SRAI could be constructed which correlated with PV and in addition neither VAS score correlated with PV. There was a moderate correlation between the TKAI and a patient SRAI using the same joints, symptoms and weightings (r = 0.6, P < 0.01). Patients can clearly report different grades of multiple symptoms in multiple joints, but such reports cannot be shown to be a reliable indicator of inflammatory activity.
Citation
Hewlett, S., Haynes, J., Shepstone, L., & Kirwan, J. R. (1995). Rheumatoid arthritis patients cannot accurately report signs of inflammatory activity. Rheumatology, 34, 547-553
Journal Article Type | Article |
---|---|
Publication Date | Jan 1, 1995 |
Journal | Rheumatology |
Print ISSN | 1462-0324 |
Publisher | Oxford University Press (OUP) |
Peer Reviewed | Peer Reviewed |
Volume | 34 |
Pages | 547-553 |
Keywords | rheumatoid arthritis, self-report, inflammatory activity, articular index, joint count |
Public URL | https://uwe-repository.worktribe.com/output/1107421 |
Publisher URL | http://rheumatology.oxfordjournals.org/cgi/reprint/34/6/547.pdf |
You might also like
Diagnosis and initial management in psoriatic arthritis: A qualitative study with patients
(2019)
Journal Article
Downloadable Citations
About UWE Bristol Research Repository
Administrator e-mail: repository@uwe.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search