Chizoba Esio-Bassey
Home gardening of yellow cassava and orange maize for the prevention of nutritional blindness in children: An economic evaluation and value of information analysis
Esio-Bassey, Chizoba; Wilson, Edward C F; Hooper, Lee; Rao, Nitya; Whitty, Jennifer A.
Authors
Edward C F Wilson
Lee Hooper
Nitya Rao
Jennifer A. Whitty
Abstract
Objectives: Vitamin A deficiency is the leading cause of childhood blindness worldwide, affecting mostly Sub-Saharan Africa. We aimed to predict the cost-effectiveness of home gardening (HG) of yellow cassava and orange maize to prevent nutritional blindness in children below 5 years and to assess the likely value of obtaining additional information in reducing uncertainty surrounding its cost-effectiveness. Methods: We developed a Markov model and carried out probabilistic sensitivity analysis with a value of information analysis. We costed resources from a societal perspective and outcomes were measured in disability-adjusted life years (DALYs). Results: HG was estimated to cost an additional Intl$395.00 per DALY averted, with a 72.27% likelihood of being cost-effective at a threshold of Intl$2800 per DALY. The expected value of information was estimated to be Intl$29 843.50 for 1 child or Intl$925 billion for 31 million Nigerian children affected by the decision. Further research is only worthwhile for 1 parameter (relative risk of low serum retinol; expected value of perfect parameter information Intl$29 854.53 per child and Intl$925 billion for 31 million children). Conclusion: HG of yellow cassava and orange maize is expected to be highly cost-effective in preventing nutritional blindness in Nigerian children. Worthwhile further research includes a cost analysis of the intervention and a high-quality randomized trial to assess the effectiveness of HG on serum retinol levels in young children.
Journal Article Type | Article |
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Acceptance Date | Aug 9, 2023 |
Online Publication Date | Aug 22, 2023 |
Publication Date | Nov 30, 2023 |
Deposit Date | Oct 5, 2023 |
Publicly Available Date | Aug 23, 2024 |
Journal | Value in Health Regional Issues |
Print ISSN | 2212-1099 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 38 |
Pages | 77-84 |
DOI | https://doi.org/10.1016/j.vhri.2023.07.002 |
Keywords | cost-effectiveness analysis; home gardening; nutritional blindness; value of information analysis; vitamin A deficiency VALUE HEALTH REG ISSUES 2023; 38:77-84 |
Public URL | https://uwe-repository.worktribe.com/output/11067690 |
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Home gardening of yellow cassava and orange maize for the prevention of nutritional blindness in children: An economic evaluation and value of information analysis
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Copyright Statement
This is the author's accepted manuscript. The final published version is available here: https://doi.org/10.1016/j.vhri.2023.07.002