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Outputs (111)

Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study (2020)
Journal Article

Background: No previous studies have validated current clinical practice guidelines for the management of non-blanching rashes in children who have received meningococcal B and C vaccinations. The aim of this study was to evaluate the performance o... Read More about Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study.

Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children (2020)
Journal Article

Background: The National Institute for Health and Care Excellence (NICE) have called for research into the role of biomarkers, and specifically procalcitonin (PCT), for the early diagnosis of serious bacterial infections (SBI) in children. The aim of... Read More about Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children.

Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial (2020)
Journal Article

Background Key challenges to the successful conduct of The Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children (EcLiPSE) trial were identified at the pre-trial stage. These included practitioner anxieties about condu... Read More about Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial.

Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials (2020)
Journal Article

Background: Alternatives to prospective informed consent enable the conduct of paediatric emergency and critical care trials. Research without prior consent (RWPC) involves practitioners approaching parents after an intervention has been given and se... Read More about Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials.