Outputs (1666)
Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms (2020)
Presentation / Conference Contribution
Summary of key findings Direct disinfection of established Pseudomonas aeruginosa biofilms by electrochemically activated solutions [ECAS] exhibited significantly greater anti-biofilm activity compared to NaOCl and HOCl at free chlorine concentratio... Read More about Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms.
Studies towards the development of a novel, screen-printed carbon-based, biosensor for the measurement of polyunsaturated fatty acids (2020)
Journal Article
This paper describes the design, development and characterisation of an electrochemical biosensor for the measurement of linoleic and α-linolenic acid, as representative free polyunsaturated fatty acids (PUFAs), that may be implicated in food safety... Read More about Studies towards the development of a novel, screen-printed carbon-based, biosensor for the measurement of polyunsaturated fatty acids.
From fast identification to resistance testing: Volatile compound profiling as a novel diagnostic tool for detection of antibiotic susceptibility (2019)
Journal Article
Widespread use of antibiotics has led to the development of antibiotic resistance in many pathogenic bacteria. If effective methods of alleviating this crisis are not applied, a return to high mortality and morbidity of the pre-antibiotic era could o... Read More about From fast identification to resistance testing: Volatile compound profiling as a novel diagnostic tool for detection of antibiotic susceptibility.
Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects (2021)
Thesis
Advances in modern chemotherapeutic regimens have led to an increase in the overall survival of leukaemia patients in recent years. However, haematopoietic stem cell transplantation (HSCT) remains the curative option for these patients. In HSCT, high... Read More about Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects.
Investigation of the antifungal and anti-aflatoxigenic potential of plant-based essential oils against aspergillus flavus in peanuts (2020)
Journal Article
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Aspergillus species are known to cause damage to food crops and are associated with opportunistic infections in humans. In the United States, significant losses have been reported in peanut pr... Read More about Investigation of the antifungal and anti-aflatoxigenic potential of plant-based essential oils against aspergillus flavus in peanuts.
Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes (2020)
Presentation / Conference Contribution
Background: The five antigens of the Yt blood group system are located on the membrane GPI‐linked erythrocyte acetylcholinesterase (AChE‐E), which is implicated in a range of clinical issues, including sleep apnoea and neurotoxin poisoning. Conformat... Read More about Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes.
Use of a nitrification inhibitor reduces nitrous oxide (N2O) emissions from compacted grassland with different soil textures and climatic conditions (2021)
Journal Article
Grassland accounts for 70 % of the global agricultural area. Grassland amended with N fertiliser, although increasing productivity, encourages the emission of the greenhouse gas nitrous oxide (N2O). Soil compaction can result in impeded water movemen... Read More about Use of a nitrification inhibitor reduces nitrous oxide (N2O) emissions from compacted grassland with different soil textures and climatic conditions.
Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2 (2021)
Journal Article
Abstract: COVID-19, caused by SARS-CoV-2, is a world-wide problem for the human population. It is known that some animal species, such as mink, can become infected and transmit the virus. However, the susceptibility of most animals is not known. Here... Read More about Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2.
Downstream signalling from molecular hydrogen (2021)
Journal Article
Molecular hydrogen (H2) is now considered to be a part of the suite of small molecules which can control cellular activity. As such it has been suggested to be used in the therapy of diseases in humans but also to be used in plant science, to enhance... Read More about Downstream signalling from molecular hydrogen.
Survivability of pathogens under different growth conditions in seawater (2017)
Journal Article
A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer (2020)
Journal Article
Background: Evidence for aspirin’s chemopreventative properties on colorectal cancer (CRC) is substantial, but its mechanism of action is not well-understood. We combined a proteomic approach with Mendelian randomization (MR) to identify possible new... Read More about A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer.
Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases (2021)
Journal Article
Oxy-hydrogen gas (HHO) is a gaseous mixture of molecular hydrogen (H2) and molecular oxygen (O2) that is generated by the electrolysis of water and delivered in a 2:1 ratio (66% and 33%, respectively) through the use of non-invasive inhalation device... Read More about Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases.
5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis (2021)
Journal Article
Background: Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps. Polyp resection prevents progression to CRC. Risk of future polyps is proportional to the number and size of polyps detected at screening, allowing i... Read More about 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis.
Training future generations to deliver evidence-based conservation and ecosystem management (2021)
Journal Article
1. To be effective, the next generation of conservation practitioners and managers need to be critical thinkers with a deep understanding of how to make evidence‐based decisions and of the value of evidence synthesis. 2. If, as educators, we do no... Read More about Training future generations to deliver evidence-based conservation and ecosystem management.
Using UAV-mounted thermal cameras to detect the presence of nesting nightjar in upland clear-fell: A case study in South Wales, UK (2021)
Journal Article
1. Confirming the presence and location of European Nightjar Caprimulgus europaeus nests is a significant fieldwork challenge in ecological monitoring. Nest sites can be located through direct observation or capture and radio tracking of breeding ind... Read More about Using UAV-mounted thermal cameras to detect the presence of nesting nightjar in upland clear-fell: A case study in South Wales, UK.
Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message (2021)
Journal Article
Alternative splicing is a highly fine-tuned regulated process and one of the main drivers of proteomic diversity across eukaryotes. The vast majority of human multi-exon genes is alternatively spliced in a cell type-and tissue-specific manner, and de... Read More about Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message.
A roadmap for genome-based phage taxonomy (2021)
Journal Article
Bacteriophage (phage) taxonomy has been in flux since its inception over four decades ago. Genome sequencing has put pressure on the classification system and recent years have seen significant changes to phage taxonomy. Here, we reflect on the state... Read More about A roadmap for genome-based phage taxonomy.
Going off-grid – The decentralised production of point-of-use drinking water (2021)
Digital Artefact
CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer (2021)
Journal Article
Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice factors and o... Read More about CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.