Outputs (1255)

Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin (2005)
Journal Article

This study presents the first three-dimensional structures of human cytosolic branched-chain aminotransferase (hBCATc) isozyme complexed with the neuroactive drug gabapentin, the hBCATc Michaelis complex with the substrate analog, 4-methylvalerate, a... Read More about Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.

In vitro method to assess the antimicrobial activity and potential efficacy of novel types of wound dressings (2005)
Journal Article

Aims: To develop a simple, reproducible in vitro static diffusion method using cellulose disks and defined species to test antimicrobial efficacy of wound dressings. Methods and Results: Cellulose disks were inoculated by immersion in cell suspension... Read More about In vitro method to assess the antimicrobial activity and potential efficacy of novel types of wound dressings.

Towards predicting spatial complexity: a learning classifier system approach to the identification of cellular automata (2005)
Presentation / Conference Contribution

This paper presents a novel approach to the programming of automata-based simulation and computation using a machine learning technique. The identification of lattice-based automata for real-world applications is cast as a data mining problem. Our ap... Read More about Towards predicting spatial complexity: a learning classifier system approach to the identification of cellular automata.

Cannabinoids and cancer: Potential for colorectal cancer therapy (2005)
Presentation / Conference Contribution

Despite extensive research into the biology of CRC (colorectal cancer), and recent advances in surgical techniques and chemotherapy, CRC continues to be a major cause of death throughout the world. Therefore it is important to develop novel chemoprev... Read More about Cannabinoids and cancer: Potential for colorectal cancer therapy.

Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium (2005)
Journal Article

We experimentally demonstrate that excitation wave-fragments in a Belousov-Zhabotinsky (BZ) medium with immobilised catalyst can be used to build elementary logical gates and circuits. Following our previous theoretical constructions [Adamatzky A. Co... Read More about Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium.

Some effects of nitrogen nutrition on caesium uptake and translocation by species in the Poaceae, Asteraceae and Caryophyllidae (2006)
Journal Article

There is current interest in managing and manipulating 137Cs transfer from soil to plants. We hypothesized that N source might affect Cs uptake by plants and report experiments that confirm this. Uptake experiments using hydroponics with a variety of... Read More about Some effects of nitrogen nutrition on caesium uptake and translocation by species in the Poaceae, Asteraceae and Caryophyllidae.

Amino acid determination using screen-printed electrochemical sensors (2005)
Journal Article

The use of a screen-printed electrochemical sensor (SPES) strip, consisting of a two-electrode system (a carbon working electrode and Ag/AgCl reference electrode), for amino acid determination is reported. The behaviour of the SPES toward cysteine an... Read More about Amino acid determination using screen-printed electrochemical sensors.

Development of a screen-printed carbon electrochemical immunosensor for picomolar concentrations of estradiol in human serum extracts (2005)
Journal Article

Investigations into the development of a prototype electrochemical immunosensor for estradiol (E2) are described. After optimising reagent loadings in a 96-well enzyme-linked immunosorbent assay (ELISA), antibodies (rabbit anti-mouse IgG and monoclon... Read More about Development of a screen-printed carbon electrochemical immunosensor for picomolar concentrations of estradiol in human serum extracts.

Voltammetric behaviour of Nitrazepam and Flunitrazepam, and their determination by Liquid-Chromatography Dual-Electrode Detection (2005)
Presentation / Conference Contribution

A phylogenetic effect on strontium concentrations in angiosperms (2006)
Journal Article

A Residual Maximum Likelihood (REML) procedure was used to compile Sr concentrations in 103 plant species from experiments with Sr concentrations in 66 plant species from the literature. There were 14 species in common between experiments and the lit... Read More about A phylogenetic effect on strontium concentrations in angiosperms.

Rapid diagnosis of gastro-intestinal infections using faecal odour (2005)
Book Chapter

This book describes how the analysis of the trace gases in exhaled breath can be used for non-invasive clinical diagnosis of disease and for monitoring the effectiveness of therapy. This approach offers an important addition to the diagnostic techniq... Read More about Rapid diagnosis of gastro-intestinal infections using faecal odour.

Comparison of an organic polymeric column and a silica-based reversed-phase for the analysis of basic peptides by high-performance liquid chromatography (2005)
Presentation / Conference Contribution

The performance of a purely polymeric and a Type B silica-based C 18 reversed-phase column was compared for the analysis of the basic peptide bradykinin and some analogues in order to assess the contribution of silanol interactions to peak shape. Goo... Read More about Comparison of an organic polymeric column and a silica-based reversed-phase for the analysis of basic peptides by high-performance liquid chromatography.

Myosin Va transports dense core secretory vesicles in pancreatic MIN6 β-cells (2005)
Journal Article

The role of unconventional myosins in neuroendocrine cells is not fully understood, with involvement suggested in the movement of both secretory vesicles and mitochondria. Here, we demonstrate colocalization of myosin Va (MyoVa) with insulin in pancr... Read More about Myosin Va transports dense core secretory vesicles in pancreatic MIN6 β-cells.

EcoBot-II: An artificial agent with a natural metabolism (2005)
Journal Article

In this paper we report the development of the robot EcoBot-II, which exhibits a primitive form of artificial symbiosis. Microbial Fuel Cells (MFCs) were used as the onboard energy supply, which consisted of bacterial cultures from sewage sludge and... Read More about EcoBot-II: An artificial agent with a natural metabolism.

The rapid detection of methyl tert-butyl ether (MtBE) in water using a prototype gas sensor system (2005)
Journal Article

Comment on letter to the editor: Magnocellular reading and dyslexia (2005)
Journal Article

Predicting inter-taxa differences in plant uptake of cesium-134/137 (2005)
Journal Article

For 134/137Cs, and many other soil contaminants, research into transfer to plants has focused on particular crops and phytoremediation candidates, producing uptake data for a small proportion of all plant taxa. Despite the significance of differences... Read More about Predicting inter-taxa differences in plant uptake of cesium-134/137.

Reaction-diffusion computers (2005)
Book

The interdisciplinary research monograph, which has been peer-reviewed by several international experts assigned by Elsevier, introduces ground breaking original results in formal paradigms, architectures and laboratory implementations of computers b... Read More about Reaction-diffusion computers.

NICE review: Not nice for patients! (2005)
Journal Article

Inhibition of CYP2E1 expression by androstenone: Relation to boar taint (2005)
Book Chapter