Outputs (684)

Chitinase 3-like 1 expression by human (MG63) osteoblasts in response to lysophosphatidic acid and 1,25-dihydroxyvitamin D3 (2016)
Journal Article

© 2016 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM) Chitinase 3-like 1, otherwise known as YKL-40, is a secreted glycoprotein purported to have a role in extracellular matrix metabolism. The first mammalian cell ty... Read More about Chitinase 3-like 1 expression by human (MG63) osteoblasts in response to lysophosphatidic acid and 1,25-dihydroxyvitamin D3.

Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm ™ ) (2016)
Journal Article

© 2016 The Author(s). Background: The rapid production and incorporation of engineered nanomaterials into consumer products alongside research suggesting nanomaterials can cause cell death and DNA damage (genotoxicity) makes in vitro assays desirabl... Read More about Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm ™ ).

Insulin receptor isoform variations in prostate cancer cells (2016)
Journal Article

� 2016 Perks, Zielinska, Wang, Jarrett, Frankow, Ladomery, Bahl, Rhodes, Oxley and Holly. Men who develop prostate cancer (PCa) increasingly have one of the co-morbidities associated with a Western lifestyle that are characterized by hyperinsulinem... Read More about Insulin receptor isoform variations in prostate cancer cells.

Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas (2016)
Journal Article

Background and research question: Gliomas represent 43% of all solid intracranial tumours, of which glioblastomas have the poorest prognosis. Recently, the human cytosolic branched-chain aminotransferase protein (hBCATc), which metabolises the branch... Read More about Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas.

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral (2016)
Journal Article

© 2016, The Author(s). The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility scr... Read More about Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral.

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling (2015)
Journal Article

Objective Colorectal cancer remains the fourth most common cause of cancer-related mortality worldwide. Here we investigate the role of nuclear factor-?B (NF-?B) co-factor B-cell CLL/lymphoma 3 (BCL-3) in promoting colorectal tumour cell survival. De... Read More about BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.

Oligonucleotide-based systems: DNA, microRNAs, DNA/RNA aptamers (2016)
Journal Article

© 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society. There are an increasing number of applications that have been developed for oligonucleotide-based biosensing systems in genetics and biomedicine. Oligonuc... Read More about Oligonucleotide-based systems: DNA, microRNAs, DNA/RNA aptamers.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2016)
Journal Article

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies... Read More about Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Understanding the risk to European protected species (bats) at onshore wind turbine sites to inform risk management (2016)
Report

The aim of this project is to determine the risks to bat populations from wind turbines in Great Britain. The project has investigated bat mortality and activity at a range of wind turbine installations across Great Britain and the results will be us... Read More about Understanding the risk to European protected species (bats) at onshore wind turbine sites to inform risk management.

Nonlinear thermal instability in a horizontal porous layer with an internal heat source and mass flow (2016)
Journal Article

© 2016, Springer-Verlag Wien. Linear and nonlinear stability analyses of Hadley–Prats flow in a horizontal fluid-saturated porous medium with a heat source are performed. The results indicate that, in the linear case, an increase in the horizontal th... Read More about Nonlinear thermal instability in a horizontal porous layer with an internal heat source and mass flow.

Double-diffusive Hadley-Prats flow in a porous medium subject to gravitational variation (2016)
Journal Article

© 2015 Elsevier Masson SAS. All rights reserved. A model for double-diffusive porous Hadley-Prats flow under the effect of a variable gravity field is explored. Both linear instability and nonlinear stability analyses are performed to assess the suit... Read More about Double-diffusive Hadley-Prats flow in a porous medium subject to gravitational variation.

Design and development of novel screen-printed microelectrode and microbiosensor arrays fabricated using ultrafast pulsed laser ablation (2016)
Journal Article

© 2016 Elsevier B.V. All rights reserved. A new generic platform for the development of microbiosensors combining screen-printing and ultrafast pulsed laser technologies has been developed, characterised and evaluated. This new platform consists of a... Read More about Design and development of novel screen-printed microelectrode and microbiosensor arrays fabricated using ultrafast pulsed laser ablation.

Application of a printed silver-based electrocatalyst for H2O2 reduction to the determination of cholesterol (2013)
Presentation / Conference Contribution

Many current clinical disorders such as hypertension, arteriosclerosis, coronary artery disease and cerebral thrombosis are associated with abnormal levels of cholesterol in blood. Therefore, the development of a reliable and simple method for choles... Read More about Application of a printed silver-based electrocatalyst for H2O2 reduction to the determination of cholesterol.

Temperature response of denitrification rate and greenhouse gas production in agricultural river marginal wetland soils (2013)
Journal Article

Soils are predicted to exhibit significant feedback to global warming via the temperature response of greenhouse gas (GHG) production. However, the temperature response of hydromorphic wetland soils is complicated by confounding factors such as oxyge... Read More about Temperature response of denitrification rate and greenhouse gas production in agricultural river marginal wetland soils.

Development of a printed HDL-cholesterol biosensor based on a novel electrocatalyst for hydrogen peroxide reduction (2013)
Journal Article

Volatile organic compounds (VOCs) found in urine and stool (2013)
Book Chapter

On loading slime mould Physarum polycephalum with metallic particles
Journal Article

Plasmodium \emph{Physarum polycephalum} is a large single cell visible with the naked eye. When inoculated on a substrate with attractants and repellents the plasmodium develops optimal networks of protoplasmic tubes which span sites of attractants (... Read More about On loading slime mould Physarum polycephalum with metallic particles.

Taking a breath for better health (2013)
Journal Article

What does your breath say about you? It might tell the world (or at least anyone at close quarters) that you didn’t brush your teeth this morning, or that you ate garlic last night. But there might also be other, subtle and important clues in there a... Read More about Taking a breath for better health.

Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception? (2013)
Presentation / Conference Contribution

Time perception is essential for task switching, and in the mammalian brain appears alongside other processes. Memristors are electronic components used as synapses and as models for neurons. The d.c. response of memristors can be considered as a typ... Read More about Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception?.

Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols (2013)
Presentation / Conference Contribution

It is not always possible for a robot to process all the information from its sensors in a timely manner and thus quick and yet valid approximations of the robot's situation are needed. Here we design hybrid control for a robot within this limit usin... Read More about Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols.