Outputs (658)

Mapping brain activity during loss of situation awareness: An EEG investigation of a basis for top-down influence on perception (2014)
Journal Article

Objective: The objective was to map brain activity during early intervals in loss of situation awareness (SA) to examine any co-activity in visual and high-order regions, reflecting grounds for top-down influences on Level 1 SA. Background: Behavior... Read More about Mapping brain activity during loss of situation awareness: An EEG investigation of a basis for top-down influence on perception.

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway (2015)
Journal Article

© 2015. Published by The Company of Biologists Ltd. Ciliopathies are a group of developmental disorders that manifest with multi-organ anomalies. Mutations in TMEM67 (MKS3) cause a range of human ciliopathies, including Meckel-Gruber and Joubert synd... Read More about The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.

Thai visitors’ expectations and experiences of explainer interaction within a science museum context (2015)
Journal Article

© The Author(s) 2015. In Western literature, there is evidence that museum explainers offer significant potential for enhancing visitors’ learning through influencing their knowledge, content, action, behaviour and attitudes. However, little research... Read More about Thai visitors’ expectations and experiences of explainer interaction within a science museum context.

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance (2014)
Journal Article

© 2014 The Authors. The angiogenic capability of colorectal carcinomas (CRC), and their susceptibility to anti-angiogenic therapy, is determined by expression of vascular endothelial growth factor (VEGF) isoforms. The intracellular protein T-cell In... Read More about Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.

Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process (2015)
Journal Article

© 2015 Chen et al. Steroids metabolism plays an important role in mammals and contributes to quality of pig meat. The main objective of this study was to identify metabolites of androstenone, 17β-estradiol and dihydrotestosterone using primary cultur... Read More about Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process.

Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee (2014)
Journal Article

© 2014 Elsevier B.V. Rohypnol (flunitrazepam) has been successfully determined in coffee by high performance liquid chromatography dual electrode detection (LC-DED) in the dual reductive mode. Initial studies were performed to optimise the chromatogr... Read More about Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee.

A strategic approach for the visualisation of the low abundance protein fatty acid binding protein 7 (2015)
Journal Article

Fatty acid binding protein 7 (FABP7) is a 15kDa protein that plays a role in fatty acid transport, solubilisation and metabolism. It has been found to be overexpressed in triple negative/basal like breast cancer patients. The role of FABP7 in these... Read More about A strategic approach for the visualisation of the low abundance protein fatty acid binding protein 7.

Effects of Lipid Composition on Bilayer Membranes Quantified by All-Atom Molecular Dynamics (2015)
Journal Article

© 2015 American Chemical Society. Biological bilayer membranes typically contain varying amounts of lamellar and nonlamellar lipids. Lamellar lipids, such as dioleoylphosphatidylcholine (DOPC), are defined by their tendency to form the lamellar phase... Read More about Effects of Lipid Composition on Bilayer Membranes Quantified by All-Atom Molecular Dynamics.

The expression of toll-like receptors in B-chronic lymphocytic leukaemia (2015)
Thesis

Chronic Lymphocytic Leukaemia (CLL) is the most common form of Leukaemia in the Western world and has a highly variable clinical course. Continuing advances in the range of therapeutic options available to clinicians require reliable prognostic indic... Read More about The expression of toll-like receptors in B-chronic lymphocytic leukaemia.

The development of electrochemical biosensors for cholesterol (2015)
Thesis

Coronary vascular disease (CVD) is the number one cause of death worldwide. According to a WHO report and global and regional projections of mortality and burden of disease, by 2030, the number of people dying from heart disease and stroke will incre... Read More about The development of electrochemical biosensors for cholesterol.

Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar (2014)
Journal Article

© 2014 New Phytologist Trust. Paternal biocontainment methods (PBMs) act by preventing pollen-mediated transgene flow. They are compromised by transgene escape via the crop-maternal line. We therefore assess the efficacy of PBMs for transgenic rapese... Read More about Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar.

Circulating prostaglandins as biomarkers for colorectal cancer? (2015)
Journal Article

Despite increases in our understanding of intestinal tumour biology, colorectal cancer remains a leading cause of cancer-related death worldwide. Most colorectal cancers develop from benign adenomas, presenting an opportunity for early detection and... Read More about Circulating prostaglandins as biomarkers for colorectal cancer?.

Suppression of microdochium nivale by phosphite in cool-season amenity turfgrasses (2015)
Thesis

The ascomycete fungus Microdochium nivale (Fr.) Samuels and Hallett (teleomorph Monographella nivalis (Schafnitt) is one of the most ubiquitous and damaging pathogens of cool-season amenity turfgrasses. Current control measures rely on inputs of chem... Read More about Suppression of microdochium nivale by phosphite in cool-season amenity turfgrasses.

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: Implications for targeting cancer stem cells (2015)
Journal Article

© 2015 Cancer Research UK. Background:LGR5 is an important marker of intestinal stem cells and performs its vital functions at the cell membrane. Despite the importance of LGR5 to both normal and cancer stem cell biology, it is not known how microenv... Read More about Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: Implications for targeting cancer stem cells.

Physiological and pathophysiological implications of micromotion activity in urinary bladder function (2015)
Journal Article

© 2014 Scandinavian Physiological Society. 'Micromotions' is a term signifying the presence of localized microcontractions and microelongations, alongside non-motile areas. The motile areas tend to shift over the bladder surface with time, and the in... Read More about Physiological and pathophysiological implications of micromotion activity in urinary bladder function.

Detection of thiol modifications by hydrogen sulfide (2015)
Book Chapter

Amperometric determination of hydrogen peroxide at a silver electrode fabricated from a recycled compact disc (2015)
Journal Article

This present study investigates the utilisation of Ag electrodes fabricated from recycled recordable compact discs (CD-R) for the amperometric determination of hydrogen peroxide. The analytical curve was linear up to at least 30 mM hydrogen peroxide... Read More about Amperometric determination of hydrogen peroxide at a silver electrode fabricated from a recycled compact disc.

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells (2014)
Journal Article

© 2014 The Authors. Approximately half of poor prognosis neuroblastomas (NBs) are characterized by pathognomonic MYCN gene amplification and MYCN over-expression. Here we present data showing that short-interfering RNA mediated depletion of the prote... Read More about Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells.

Do carcinogens have a threshold dose? Pro and contra (2015)
Book Chapter

With sound understanding of biological concepts, the notion of threshold effect levels has grown in acceptance especially for electrophile-induced mutations. However, mutagenesis is one part of the exposure-to-tumor process in chemical carcinogenesis... Read More about Do carcinogens have a threshold dose? Pro and contra.

The impacts of new street light technologies: Experimentally testing the effects on bats of changing from low-pressure sodium to white metal halide (2015)
Journal Article

© 2015 The Authors. All rights reserved. Artificial light at night is a major feature of anthropogenic global change and is increasingly recognized as affecting biodiversity, often negatively. On a global scale, newer technology white lights are repl... Read More about The impacts of new street light technologies: Experimentally testing the effects on bats of changing from low-pressure sodium to white metal halide.