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Outputs (1031)

Investigation of the effect of pressure on retention of small molecules using reversed-phase ultra-high-pressure liquid chromatography (2008)
Journal Article

The effect of inlet pressure on the retention of a series of low molecular weight acids, bases and neutrals, was investigated at constant temperature in reversed-phase liquid chromatography using a commercial ultra-high-pressure system (Waters UPLC i... Read More about Investigation of the effect of pressure on retention of small molecules using reversed-phase ultra-high-pressure liquid chromatography.

Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase (2008)
Journal Article

The human branched chain aminotransferase enzymes are key regulators of glutamate metabolism in the brain and are among a growing number of redox-sensitive proteins. Studies that use thiol-specific reagents and electrospray ionization mass spectromet... Read More about Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase.

Disturbance in energy metabolism induced by diclofenac, isoniazid, paracetamol and galactosamine in a liver spheroid model (2008)
Presentation / Conference Contribution

The liver plays a central role in the metabolism and transformation of energy-generating substances. Mitochondria and different metabolic pathways in hepatocytes interrelate and are often vulnerable targets of toxicants. Using animal tests it is diff... Read More about Disturbance in energy metabolism induced by diclofenac, isoniazid, paracetamol and galactosamine in a liver spheroid model.

Determination of flunitrazepam and nitrazepam in beverage samples by liquid chromatography with dual electrode detection using a carbon fibre veil electrode (2008)
Journal Article

Both nitrazepam and flunitrazepam have been determined by high-performance liquid chromatography dual electrode detection (LC-DED) in the reductive-reductive mode, using a carbon fibre veil electrode (CFVE) in conjugation with a glassy carbon electro... Read More about Determination of flunitrazepam and nitrazepam in beverage samples by liquid chromatography with dual electrode detection using a carbon fibre veil electrode.

Development and application of a simple colorimetric assay reveals widespread distribution of sodium channel mutations in Thai populations of Aedes aegypti (2008)
Journal Article

Dengue fever and its more serious complications dengue haemorrhagic fever and dengue shock syndrome are growing public health problems in tropical and subtropical countries. In the absence of a vaccine, most dengue control programmes rely heavily on... Read More about Development and application of a simple colorimetric assay reveals widespread distribution of sodium channel mutations in Thai populations of Aedes aegypti.

Physical and biological controls on the in situ kinetic isotope effect associated with oxidation of atmospheric CH4 in mineral soils (2008)
Journal Article

The amounts and δ13C values of CH4 at subambient concentrations in soil gas were determined along depth profiles in a U.K. grassland (Bronydd Mawr) and woodland (Leigh Woods). The data were used to determine in situ kinetic isotope effects (KIEs) ass... Read More about Physical and biological controls on the in situ kinetic isotope effect associated with oxidation of atmospheric CH4 in mineral soils.

A sensor system for monitoring the simple gases hydrogen, carbon monoxide, hydrogen sulfide, ammonia and ethanol in exhaled breath (2008)
Journal Article

A sensor array system was constructed incorporating electrochemical sensors for hydrogen, carbon monoxide, hydrogen sulfide and ethanol, a ceramic sensor for total volatiles and a dye-based optical ammonia sensor. The system was calibrated using stan... Read More about A sensor system for monitoring the simple gases hydrogen, carbon monoxide, hydrogen sulfide, ammonia and ethanol in exhaled breath.