Dr Alison Cobb's Outputs (3)

The effects of 7.5% carbon dioxide inhalation on task performance in healthy volunteers (2011)
Journal Article

Studies have shown that anxiety can positively or negatively affect performance with respect to focusing of attention or distractibility, subjective workload and effort (Humphreys and Revelle, 1984). The inhalation of carbon dioxide (CO2) is associat... Read More about The effects of 7.5% carbon dioxide inhalation on task performance in healthy volunteers.

Preliminary evidence of anxiolytic effects of the CRF1 receptor antagonist R317573 in the 7.5% CO2 proof-of-concept experimental model of human anxiety (2011)
Journal Article

We have validated the use of prolonged inhalation of 7.5% carbon dioxide (CO2) as a human model of anxiety and have shown that drugs from two prototypical classes of anxiolytics, benzodiazepines and a serotonin reuptake inhibitor, attenuate CO2-induc... Read More about Preliminary evidence of anxiolytic effects of the CRF1 receptor antagonist R317573 in the 7.5% CO2 proof-of-concept experimental model of human anxiety.

Effects of 7.5% CO2 inhalation on allocation of spatial attention to facial cues of emotional expression (2011)
Journal Article

Increased vigilance to threat-related stimuli is thought to be a core cognitive feature of anxiety. We sought to investigate the cognitive impact of experimentally induced anxiety, by means of a 7.5% CO2 challenge, which acts as an unconditioned anxi... Read More about Effects of 7.5% CO2 inhalation on allocation of spatial attention to facial cues of emotional expression.