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All Outputs (79)

Lipotoxicity and the role of translationally controlled tumour protein (TCTP) in pancreatic β-cell survival (2014)
Thesis

Introduction: Diabetes affects more than 346 million individuals worldwide. Some 90% of diabetics have type 2 diabetes mellitus, which is frequently associated with obesity and hyperlipidemia as well as hyperglycaemia. There is ample evidence that... Read More about Lipotoxicity and the role of translationally controlled tumour protein (TCTP) in pancreatic β-cell survival.

An analysis of the introduction of new technologies within the hybrid imaging workforce using organisational ethnography (2014)
Thesis

The introduction of hybrid imaging technology has begun to redefine working practice in nuclear medicine. Emerging hybrid imaging techniques and evolving roles have created opportunities and challenges for nuclear medicine practitioners, and this i... Read More about An analysis of the introduction of new technologies within the hybrid imaging workforce using organisational ethnography.

The investigation of the hBCAT proteins in control and diseased human brains: Implications for glutamate toxicity in Alzheimer’s disease (2014)
Thesis

Introduction & Aims: The distribution of the BCAT proteins has been extensively mapped in rodent models, and metabolic studies have established that BCAT transamination in the rodent brain is responsible for 30% of de novo glutamate synthesis. Howeve... Read More about The investigation of the hBCAT proteins in control and diseased human brains: Implications for glutamate toxicity in Alzheimer’s disease.