All Outputs (29)
Hybridization Between Brassica napus and B. rapa on a National Scale in the United Kingdom (2003)
Journal Article
Measures blocking hybridization would prevent or reduce biotic or environmental change caused by gene flow from genetically modified (GM) crops to wild relatives. The efficacy of any such measure depends on hybrid numbers within the legislative regio... Read More about Hybridization Between Brassica napus and B. rapa on a National Scale in the United Kingdom.
Site of intracellular expression of ß-catenin influences the outcome in sporadic colorectal cancer (2003)
Journal Article
Background: Stabilisation and nuclear translocation of beta-catenin are suggested to be the early events in the colorectal carcinogenesis. Nuclear accumulation of beta-catenin was associated with high-grade tumour and increased cell proliferation in... Read More about Site of intracellular expression of ß-catenin influences the outcome in sporadic colorectal cancer.
Murine Denys-Drash syndrome: Evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis (2003)
Journal Article
Denys-Drash syndrome (DDS) is caused by dominant mutations of the Wilms' tumour suppressor gene, WT1, and characterized by a nephropathy involving diffuse mesangial sclerosis, male pseudohermaphroditism and/ or Wilms' tumourigenesis. Previously, we r... Read More about Murine Denys-Drash syndrome: Evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis.
British newspapers priviledge health and medicine topics over other science news (2003)
Journal Article
This study examines coverage of science, health and medicine in five UK national newspapers: three broadsheets, a mid-sheet and a tabloid. The content analysis is compared with a quantitative survey of members of the Association of British Science Wr... Read More about British newspapers priviledge health and medicine topics over other science news.
The synthesis of novel 3-substituted pyrrole monomers possessing chiral side groups: A study of their chemical polymerisation and the assessment of their chiral discrimination properties (2003)
Journal Article
Novel 3-substituted pyrrole monomers possessing chiral side groups were synthesised. These compounds were successfully polymerised with ferric salts and the polymer materials fabricated into sensors. The sensors were found to elicit differential chan... Read More about The synthesis of novel 3-substituted pyrrole monomers possessing chiral side groups: A study of their chemical polymerisation and the assessment of their chiral discrimination properties.
Rationalization of retention and overloading behavior of basic compounds in reversed-phase HPLC using low ionic strength buffers suitable for mass spectrometric detection (2003)
Journal Article
The retention and overloading behavior of some basic (and acidic) compounds has been studied on different RP-HPLC columns in buffers of varying ionic strength. Anomalous retention patterns of acids and bases were found on one phase in low-pH, volatil... Read More about Rationalization of retention and overloading behavior of basic compounds in reversed-phase HPLC using low ionic strength buffers suitable for mass spectrometric detection.
Nitric oxide signalling in plants (2003)
Journal Article
Recently nitric oxide (NO) has emerged as a key signalling molecule in plants. Here we review the potential sources of endogenous NO, outline the biological processes likely to be mediated by NO, and discuss the downstream signalling processes by whi... Read More about Nitric oxide signalling in plants.
Experimental reaction-diffusion chemical processors for robot path planning (2003)
Journal Article
In this paper we discuss the experimental implementation of a chemical reaction-diffusion processor for robot motion planning in terms of finding the shortest collision-free path for a robot moving in an arena with obstacles. These reaction-diffusion... Read More about Experimental reaction-diffusion chemical processors for robot path planning.
Thick film organic vapour sensors based on binary mixtures of metal oxides (2003)
Journal Article
Previously, composite sensors incorporating differing proportions of tin dioxide and zinc oxide were reported which exhibited high sensitivity to a range of organic vapours under dry conditions (0% relative humidity, RH). Most importantly, the compos... Read More about Thick film organic vapour sensors based on binary mixtures of metal oxides.
New labelling rules for meat products (2003)
Journal Article
Food labelling, burden to industry or necessary red tape (2003)
Journal Article
Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger one (2003)
Journal Article
The Wilms' tumour suppressor gene WT1 encodes a protein involved in urogenital development and disease. The salient feature of WT1 is the presence of four 'Krüppel'-type C2-H2 zinc fingers in the C-terminus. Uniquely to WTI, an evolutionarily conserv... Read More about Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger one.
Irrationality, suboptimality, and the evolutionary context (2003)
Journal Article
We propose that a direct analogy can be made between optimal behaviour in animals and rational behaviour in humans, and that lessons learned by the study of the former can be applied to the latter. Furthermore, we suggest that, to understand human de... Read More about Irrationality, suboptimality, and the evolutionary context.
A prototype sensor system for the early detection of microbially linked spoilage in stored wheat grain (2003)
Journal Article
Spencer-Phillips was Co-Investigator, the lead biologist in this HGCA-funded multi-disciplinary work, and co-wrote the paper. The grant was based on his expertise in the microbiology of post-harvest spoilage.
Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not (2003)
Journal Article
In postnatal life, mesenchymal stem cells (MSC) self-replicate, proliferate and differentiate into mesenchymal tissues, including bone, fat, tendon, muscle and bone marrow (BM) stroma. Possible clinical applications for MSC in stem cell transplantati... Read More about Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not.
Uptake of 134Cs by four species from the Asteraceae and two varieties from the Chenopodiaceae grown in two types of Chinese soil (2003)
Journal Article
This study investigated the uptake of 134Cs by Lactuca sativa L., Silybum marianum Gaertn., Centaurea cyanus L., Carthamus tinctorius L. from the Asteraceae, and Beta vulgaris L. var. 'Lutiancai' and Beta vulgaris L. var. 'Hongtiancai' from the Cheno... Read More about Uptake of 134Cs by four species from the Asteraceae and two varieties from the Chenopodiaceae grown in two types of Chinese soil.
Syntheses and polymerizations of (E)-2-styrylfurans and an investigation of their electrorheological properties (2003)
Journal Article
Novel furan compounds, which incorporate phenyl rings separated by alkene spacers, have been synthesized. Chemical polymerization of these compounds yielded black brittle powders, suspensions of which were found to exhibit significant electrorheologi... Read More about Syntheses and polymerizations of (E)-2-styrylfurans and an investigation of their electrorheological properties.
Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate β-lyases, but turnover leads to inactivation (2003)
Journal Article
The mitochondrial and cytosolic branched-chain aminotransferases (BCATm and BCATc) are homodimers in the fold type IV class of pyridoxal 5′-phosphate-containing enzymes that also contains D-amino acid aminotransferase and 4-amino-4-deoxychorismate ly... Read More about Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate β-lyases, but turnover leads to inactivation.
A prototype sensor system for the early detection of microbially linked spoilage in stored wheat grain (2003)
Journal Article
Sensors based on composites of metal oxides were fabricated and tested extensively under high-humidity and high-flow conditions with exposure to vapours reported to increase in the headspace of wheat grain (Triticum aestivum cv Hereward) colonized by... Read More about A prototype sensor system for the early detection of microbially linked spoilage in stored wheat grain.