α- and β-secretase: Profound changes in Alzheimer's disease
(2002)
Journal Article
The amyloid plaque, a neuropathological hallmark of Alzheimer's disease, is produced by the deposition of β-amyloid (Aβ) peptide, which is cleaved from Amyloid Precursor Protein (APP) by the enzyme β-secretase. Only small amounts of Aβ form in normal... Read More about α- and β-secretase: Profound changes in Alzheimer's disease.