All Outputs (1020)

Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines (2017)
Journal Article
Horley, N. J., Beresford, K. J., Chawla, T., McCann, G. J., Ruparelia, K. C., Gatchie, L., …Chaudhuri, B. (2017). Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. European Journal of Medicinal Chemistry, 129, 159-174. https://doi.org/10.1016/j.ejmech.2017.02.016

© 2017 Elsevier Masson SAS The structure of alpha-napthoflavone (ANF), a potent inhibitor of CYP1A1 and CYP1B1, mimics the structure of chalcones. Two potent CYP1B1 inhibitors 7k (DMU2105) and 6j (DMU2139) have been identified from two series of syn... Read More about Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.

Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance (2017)
Journal Article
Satti, N. K., Williams, I. S., Joshi, P., Gatchie, L., Sharma, M., Vishwakarma, R. A., …Bharate, S. B. (2017). Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance. Bioorganic and Medicinal Chemistry Letters, 27(16), 3683-3687. https://doi.org/10.1016/j.bmcl.2017.07.010

© 2017 Elsevier Ltd Inhibitors of CYP1 enzymes may play vital roles in the prevention of cancer and overcoming chemo-resistance to anticancer drugs. In this letter, we report synthesis of twenty-three pyrrole based heterocyclic chalcones which were s... Read More about Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance.

Getting smart about urban mobility – Aligning the paradigms of smart and sustainable (2016)
Journal Article
Lyons, G. (2018). Getting smart about urban mobility – Aligning the paradigms of smart and sustainable. Transportation Research Part A: Policy and Practice, 115, 4-14. https://doi.org/10.1016/j.tra.2016.12.001

© 2016 Elsevier Ltd The digital age continues its advance, bringing with it remarkable technological possibilities. Such possibilities are founded upon an increasingly fine-grained electronic connectivity of people, places and objects allied to power... Read More about Getting smart about urban mobility – Aligning the paradigms of smart and sustainable.

Bread and roses: A gender perspective on environmental justice and public health (2016)
Journal Article
Bell, K. (2016). Bread and roses: A gender perspective on environmental justice and public health. International Journal of Environmental Research and Public Health, 13(10), Article 1005. https://doi.org/10.3390/ijerph13101005

Gender continues to be a relatively marginal issue in environmental justice debates and yet it remains an important aspect of injustice. To help redress the balance, this article explores women’s experience of environmental justice through a review o... Read More about Bread and roses: A gender perspective on environmental justice and public health.

Biphenyl urea derivatives as selective CYP1B1 inhibitors (2016)
Journal Article
Chaudhuri, B., Jayaprakash, V., Bharate, S. B., Joshi, P., Williams, I. S., Horley, N., …Sinha, B. N. (2016). Biphenyl urea derivatives as selective CYP1B1 inhibitors. Organic and Biomolecular Chemistry, 14(38), 8931-8936. https://doi.org/10.1039/c6ob01506a

© 2016 The Royal Society of Chemistry. Highly selective CYP1B1 inhibitors have potential in the treatment of hormone-induced breast and prostate cancers. Mimicry of potent and selective CYP1B1 inhibitors, α-naphthoflavone and stilbenes, revealed that... Read More about Biphenyl urea derivatives as selective CYP1B1 inhibitors.

Automated construction of variable density navigable networks in a 3D indoor environment for emergency response (2016)
Journal Article
Boguslawski, P., Mahdjoubi, L., Zverovich, V., & Fadli, F. (2016). Automated construction of variable density navigable networks in a 3D indoor environment for emergency response. Automation in Construction, 72(2), 115-128. https://doi.org/10.1016/j.autcon.2016.08.041

© 2016 Elsevier B.V. Widespread human-induced or natural threats on buildings and their users have made preparedness and rapid response crucial issues for saving human lives. The ability to identify the paths of egress during an emergency is critical... Read More about Automated construction of variable density navigable networks in a 3D indoor environment for emergency response.

Transport analysis in an uncertain world (2016)
Journal Article
Lyons, G. (2016). Transport analysis in an uncertain world. Transport Reviews, 36(5), 553-557. https://doi.org/10.1080/01441647.2016.1194613

This short article reflects upon the task of informing policymaking and investment decisions in times of deep uncertainty, in the face of problems that are more 'wicked' than 'tame' and in the context of ever present biases.

A review into the use of ceramics in microbial fuel cells (2016)
Journal Article
Winfield, J., Gajda, I., Greenman, J., & Ieropoulos, I. (2016). A review into the use of ceramics in microbial fuel cells. Bioresource Technology, 215, 296-303. https://doi.org/10.1016/j.biortech.2016.03.135

© 2016 The Authors. Microbial fuel cells (MFCs) offer great promise as a technology that can produce electricity whilst at the same time treat wastewater. Although significant progress has been made in recent years, the requirement for cheaper materi... Read More about A review into the use of ceramics in microbial fuel cells.

Artificial Cognition for Social Human-Robot Interaction: An Implementation (2016)
Journal Article
Lemaignan, S., Warnier, M., Sisbot, E. A., Clodic, A., & Alami, R. (2017). Artificial Cognition for Social Human-Robot Interaction: An Implementation. Artificial Intelligence, 247, 45-69. https://doi.org/10.1016/j.artint.2016.07.002

© 2017 The Authors Human–Robot Interaction challenges Artificial Intelligence in many regards: dynamic, partially unknown environments that were not originally designed for robots; a broad variety of situations with rich semantics to understand and i... Read More about Artificial Cognition for Social Human-Robot Interaction: An Implementation.

Risk perception and vulnerability of value: a study in the context of commercial property sector (2016)
Journal Article
Bhattacharya-Mis, N., & Lamond, J. (2016). Risk perception and vulnerability of value: a study in the context of commercial property sector. International Journal of Strategic Property Management, 20(3), 252-264. https://doi.org/10.3846/1648715X.2016.1188174

© 2016 The Author(s). Published by Vilnius Gediminas Technical University (VGTU) Press, and Taylor & Francis. The research was developed linking the impact of flood risk on utility, desirability and marketability related to vulnerability of commerc... Read More about Risk perception and vulnerability of value: a study in the context of commercial property sector.

A social and spatial analysis of emissions from private vehicle use in Great Britain (2016)
Journal Article
Chatterton, T., & Barnes, J. (2016). A social and spatial analysis of emissions from private vehicle use in Great Britain. WIT Transactions on Ecology and the Environment, 207, 99-110. https://doi.org/10.2495/AIR160101

This paper will describe a new approach to source apportionment of transport emissions that moves away from traditional approaches which have allocated emissions to point of use, or by journey purpose. Instead, emissions will be attributed spatially... Read More about A social and spatial analysis of emissions from private vehicle use in Great Britain.

Microalgae as substrate in low cost terracotta-based microbial fuel cells: Novel application of the catholyte produced (2016)
Journal Article
Ieropoulos, I. A., Hanczyc, M. M., Greenman, J., Ortiz-Martínez, V. M., Gajda, I., Salar-García, M. J., …Ieropoulos, I. (2016). Microalgae as substrate in low cost terracotta-based microbial fuel cells: Novel application of the catholyte produced. Bioresource Technology, 209, 380-385. https://doi.org/10.1016/j.biortech.2016.02.083

© 2016 Elsevier Ltd. In this work, the by-product generated during the operation of cylindrical MFCs, made out of terracotta material, is investigated as a feasible means of degrading live microalgae for the first time. In addition to the low cost ma... Read More about Microalgae as substrate in low cost terracotta-based microbial fuel cells: Novel application of the catholyte produced.

Scaling-up of a novel, simplified MFC stack based on a self-stratifying urine column (2016)
Journal Article
Walter, X. A., Gajda, I., Forbes, S., Winfield, J., Greenman, J., & Ieropoulos, I. (2016). Scaling-up of a novel, simplified MFC stack based on a self-stratifying urine column. Biotechnology for Biofuels, 9(1), https://doi.org/10.1186/s13068-016-0504-3

© 2016 Walter et al. Background: The microbial fuel cell (MFC) is a technology in which microorganisms employ an electrode (anode) as a solid electron acceptor for anaerobic respiration. This results in direct transformation of chemical energy into e... Read More about Scaling-up of a novel, simplified MFC stack based on a self-stratifying urine column.

Learning by teaching a robot: The case of handwriting (2016)
Journal Article
Lemaignan, S., Jacq, A., Hood, D., Garcia, F., Paiva, A., & Dillenbourg, P. (2016). Learning by teaching a robot: The case of handwriting. IEEE Robotics and Automation Magazine, 23(2), 56-66. https://doi.org/10.1109/MRA.2016.2546700

© 1994-2011 IEEE. Thomas (all children's names have been changed) is five and a half years old and has been diagnosed with visuoconstructive deficits. He is under the care of an occupational therapist and tries to work around his inability to draw le... Read More about Learning by teaching a robot: The case of handwriting.

The Symmetry of Partner Modelling (2016)
Journal Article
Dillenbourg, P., Lemaignan, S., Sangin, M., Nova, N., & Molinari, G. (2016). The Symmetry of Partner Modelling. International Journal of Computer-Supported Collaborative Learning, 11(2), 227-253. https://doi.org/10.1007/s11412-016-9235-5

© 2016, International Society of the Learning Sciences, Inc. Collaborative learning has often been associated with the construction of a shared understanding of the situation at hand. The psycholinguistics mechanisms at work while establishing common... Read More about The Symmetry of Partner Modelling.

The EVIDENCE project: Measure no. 17 - Travel and passenger information (2016)
Journal Article
Calvert, T. (2016). The EVIDENCE project: Measure no. 17 - Travel and passenger information. World Transport Policy and Practice, 22(1/2), 162-170

This paper is taken from the findings of the EU Evidence project. This project provides evidence that sustainable transport interventions and spending have as much to contribute to wider societal goals and strongly posi¬tive Benefit Cost Analysis res... Read More about The EVIDENCE project: Measure no. 17 - Travel and passenger information.

A critical review of the robustness of the UK government’s air quality plan and expected compliance dates (2016)
Journal Article
Williams, B., Barnes, J., Chatterton, T., Hayes, E. T., & Longhurst, J. (2016). A critical review of the robustness of the UK government’s air quality plan and expected compliance dates. WIT Transactions on Ecology and the Environment, 207, 1-9. https://doi.org/10.2495/AIR160011

Globally, poor air quality is the most significant environmental health concern. Across Europe, 400,000 deaths were attributed to air pollution in 2012, whilst in the UK over 50,000 deaths per year are due to a combination of gaseous and particulate... Read More about A critical review of the robustness of the UK government’s air quality plan and expected compliance dates.

Unfamiliar fuel: How the UK public views the infrastructure required to supply hydrogen for road transport (2016)
Journal Article
Bellaby, P., Upham, P., Flynn, R., & Ricci, M. (2016). Unfamiliar fuel: How the UK public views the infrastructure required to supply hydrogen for road transport. International Journal of Hydrogen Energy, 41(15), 6534-6543. https://doi.org/10.1016/j.ijhydene.2016.03.024

Copyright © 2016, Hydrogen Energy Publications, LLC. In 2007, under contract to the UK Department for Transport, we engaged with the public about the infrastructure to supply hydrogen for transport. We combined a quota-sample survey of 1003 across th... Read More about Unfamiliar fuel: How the UK public views the infrastructure required to supply hydrogen for road transport.

Guidance for transport planning and policymaking in the face of an uncertain future (2016)
Journal Article
Lyons, G., & Davidson, C. (2016). Guidance for transport planning and policymaking in the face of an uncertain future. Transportation Research Part A: Policy and Practice, 88, 104-116. https://doi.org/10.1016/j.tra.2016.03.012

Uncertainty of outcome is widely recognised as a concern facing decision-makers and their advisors. In a number of spheres of policy, it appears uncertainty has intensified in the face of globalisation, economic instability, climate change, technolog... Read More about Guidance for transport planning and policymaking in the face of an uncertain future.

On hybrid circuits exploiting thermistive properties of slime mould (2016)
Journal Article
Walter, X. A., Horsfield, I., Mayne, R., Ieropoulos, I. A., & Adamatzky, A. (2016). On hybrid circuits exploiting thermistive properties of slime mould. Scientific Reports, 6(23924), https://doi.org/10.1038/srep23924

Slime mould Physarum polycephalum is a single cell visible by the unaided eye. Let the slime mould span two electrodes with a single protoplasmic tube: if the tube is heated to approximately ≈40 °C, the electrical resistance of the protoplasmic tube... Read More about On hybrid circuits exploiting thermistive properties of slime mould.