Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia

Ashby, Emma L.; Hull, Jonathon; Kehoe, Patrick G.; Hutson, Susan M.; Ashby, Emma; Hull, Jonathan; Kehoe, Patrick; Hutson, Susan; Kierzkowska, Marta; Conway, Myra E.

doi:10.1007/s11064-016-1855-7

All Outputs (2)

Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas (2016)
Journal Article

Background and research question: Gliomas represent 43% of all solid intracranial tumours, of which glioblastomas have the poorest prognosis. Recently, the human cytosolic branched-chain aminotransferase protein (hBCATc), which metabolises the branch... Read More about Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas.

Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia (2016)
Journal Article

© 2016, The Author(s). Cytosolic and mitochondrial human branched chain aminotransferase (hBCATc and hBCATm, respectively) play an integral role in brain glutamate metabolism. Regional increased levels of hBCATc in the CA1 and CA4 region of Alzheimer... Read More about Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia.