Evaluation of the efficacy of electrochemically activated solutions against nosocomial pathogens and bacterial endospores

Salisbury, V. C.; Robinson, Gareth M.; Greenman, John; Reynolds, Darren M.; Lee, S. W.H.

doi:10.1111/j.1472-765X.2009.02790.x

All Outputs (8)

The control of waterborne pathogenic bacteria in fresh water using a biologically active filter (2022)
Journal Article

The aim of this study was to investigate the control of three species of bacteria commonly associated with biologically contaminated water, using biofiltration. In this study, a laboratory-scale biofilter system was used to investigate the control of... Read More about The control of waterborne pathogenic bacteria in fresh water using a biologically active filter.

Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected (2021)
Journal Article

Tumour microenvironments are hallmarked in many cancer types. In haematological malignancies, bone marrow (BM) mesenchymal stromal cells (MSC) protect malignant cells from drug-induced cytotoxicity. However, less is known about malignant impact on su... Read More about Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected.

CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML (2018)
Journal Article

© 2018 Elsevier Ltd CPX-351, a liposomal formulation co-encapsulating cytarabine and daunorubicin (DNR) in a synergistic 5:1 M ratio, has shown favourable response in newly diagnosed elderly high-risk AML. This study assessed intracellular ara-CTP le... Read More about CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML.

Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay (2013)
Journal Article

The main aim of this study was to develop a standardized experimental assay to enable differential antimicrobial comparisons of test biocidal aerosols. This study represents the first chlorine-matched comparative assessment of the antimicrobial activ... Read More about Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay.

The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions (2013)
Journal Article

Electrochemically activated solutions (ECAS) are generated by electrolysis of NaCl solutions, and demonstrate broad spectrum antimicrobial activity and high environmental compatibility. The biocidal efficacy of ECAS at the point of production is wide... Read More about The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions.

Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments (2012)
Journal Article

Due to the limitations associated with the use of existing biocidal agents, there is a need to explore new methods of disinfection to help maintain effective bioburden control, especially within the healthcare environment. The transformation of low m... Read More about Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments.

Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides (2011)
Journal Article

Traditional microbiological techniques are used to provide reliable data on the rate and extent of kill for a range of biocides. However, such techniques provide very limited data regarding the initial rate of kill of fast-acting biocides over very s... Read More about Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides.

Evaluation of the efficacy of electrochemically activated solutions against nosocomial pathogens and bacterial endospores (2010)
Journal Article

Aims: Electrochemically activated solutions (ECAS) are generated from halide salt solutions via specially designed electrolytic cells. The active solutions are known to possess high biocidal activity against a wide range of target microbial species,... Read More about Evaluation of the efficacy of electrochemically activated solutions against nosocomial pathogens and bacterial endospores.