All Outputs (9)

Conservative management versus invasive management of significant traumatic pneumothoraces in the emergency department (the CoMiTED trial): A study protocol for a randomised non-inferiority trial (2024)
Journal Article
Blythe, N. M., Coates, K., Benger, J. R., Annaw, A., Banks, J., Clement, C., …Carlton, E. (2024). Conservative management versus invasive management of significant traumatic pneumothoraces in the emergency department (the CoMiTED trial): A study protocol for a randomised non-inferiority trial. BMJ Open, 14(6), Article e087464. https://doi.org/10.1136/bmjopen-2024-087464

Introduction: Traumatic pneumothoraces are present in one of five victims of severe trauma. Current guidelines advise chest drain insertion for most traumatic pneumothoraces, although very small pneumothoraces can be managed with observation at the t... Read More about Conservative management versus invasive management of significant traumatic pneumothoraces in the emergency department (the CoMiTED trial): A study protocol for a randomised non-inferiority trial.

The RELIEF feasibility trial: Topical lidocaine patches in older adults with rib fractures (2024)
Journal Article
Clout, M., Turner, N., Clement, C., Braude, P., Benger, J., Gagg, J., …Carlton, E. (in press). The RELIEF feasibility trial: Topical lidocaine patches in older adults with rib fractures. Emergency Medicine Journal, https://doi.org/10.1136/emermed-2024-213905

Background: Lidocaine patches, applied over rib fractures, may reduce pulmonary complications in older patients. Known barriers to recruiting older patients in emergency settings necessitate a feasibility trial. We aimed to establish whether a defini... Read More about The RELIEF feasibility trial: Topical lidocaine patches in older adults with rib fractures.

Implementation of the CHIldren with acute COugh (CHICO) intervention to improve antibiotics management: A qualitative study in primary care (2024)
Journal Article
Clement, C., Ingram, J., Cabral, C., Blair, P. S., Hay, A. D., Seume, P., & Horwood, J. (2024). Implementation of the CHIldren with acute COugh (CHICO) intervention to improve antibiotics management: A qualitative study in primary care. British Journal of General Practice, 74(743), e401-e407. https://doi.org/10.3399/BJGP.2023.0330

BACKGROUND: Childhood respiratory tract infections (RTIs) are common and can lead to unnecessary antibiotic use and antimicrobial resistance. The CHIldren with COugh (CHICO) intervention incorporates a clinician-focused algorithm (STARWAVe) to predic... Read More about Implementation of the CHIldren with acute COugh (CHICO) intervention to improve antibiotics management: A qualitative study in primary care.

How surgical Trainee Research Collaboratives achieve success: A mixed methods study to develop trainee engagement strategies. (2023)
Journal Article
Clement, C., Coulman, K., Heywood, N., Pinkney, T., Blazeby, J., Blencowe, N. S., …Lane, J. A. (2023). How surgical Trainee Research Collaboratives achieve success: A mixed methods study to develop trainee engagement strategies. BMJ Open, 13(12), Article e072851. https://doi.org/10.1136/bmjopen-2023-072851

This study aimed to understand the role of surgical Trainee Research Collaboratives (TRCs) in conducting randomised controlled trials and identify strategies to enhance trainee engagement in trials. This is a mixed methods study. We used observation... Read More about How surgical Trainee Research Collaboratives achieve success: A mixed methods study to develop trainee engagement strategies..

Multi-faceted intervention to improve management of antibiotics for children presenting to primary care with acute cough and respiratory tract infection (CHICO): efficient cluster randomised controlled trial (2023)
Journal Article
Blair, P. S., Young, G., Clement, C., Dixon, P., Seume, P., Ingram, J., …Hay, A. D. (2023). Multi-faceted intervention to improve management of antibiotics for children presenting to primary care with acute cough and respiratory tract infection (CHICO): efficient cluster randomised controlled trial. BMJ, 381(8380), Article e072488. https://doi.org/10.1136/bmj-2022-072488

Objective: To assess whether an easy-to-use multifaceted intervention for children presenting to primary care with respiratory tract infections would reduce antibiotic dispensing, without increasing hospital admissions for respiratory tract infection... Read More about Multi-faceted intervention to improve management of antibiotics for children presenting to primary care with acute cough and respiratory tract infection (CHICO): efficient cluster randomised controlled trial.

Can primary care research be conducted more efficiently using routinely reported practice-level data: A cluster randomised controlled trial conducted in England? (2022)
Journal Article
Blair, P. S., Ingram, J., Clement, C., Young, G., Seume, P., Taylor, J., …Hay, A. D. (2022). Can primary care research be conducted more efficiently using routinely reported practice-level data: A cluster randomised controlled trial conducted in England?. BMJ Open, 12(7), Article e061574. https://doi.org/10.1136/bmjopen-2022-061574

Objectives Conducting randomised controlled trials (RCTs) in primary care is challenging; recruiting patients during time-limited or remote consultations can increase selection bias and physical access to patients' notes is costly and time-consuming.... Read More about Can primary care research be conducted more efficiently using routinely reported practice-level data: A cluster randomised controlled trial conducted in England?.

Best-BRA (Is subpectoral or prepectoral implant placement best in immediate breast reconstruction?): A protocol for a pilot randomised controlled trial of subpectoral versus prepectoral immediate implant-based breast reconstruction in women following mastectomy (2021)
Journal Article
Roberts, K., Mills, N., Metcalfe, C., Lane, A., Clement, C., Hollingworth, W., …Potter, S. (2021). Best-BRA (Is subpectoral or prepectoral implant placement best in immediate breast reconstruction?): A protocol for a pilot randomised controlled trial of subpectoral versus prepectoral immediate implant-based breast reconstruction in women following mastectomy. BMJ Open, 11(11), Article e050886. https://doi.org/10.1136/bmjopen-2021-050886

Background Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure following mastectomy. IBBR techniques are evolving rapidly, with mesh-assisted subpectoral reconstruction becoming the standard of care and... Read More about Best-BRA (Is subpectoral or prepectoral implant placement best in immediate breast reconstruction?): A protocol for a pilot randomised controlled trial of subpectoral versus prepectoral immediate implant-based breast reconstruction in women following mastectomy.

Parents and GPs' understandings and beliefs about food allergy testing in children with eczema: Qualitative interview study within the Trial of Eczema allergy Screening Tests (TEST) feasibility trial (2020)
Journal Article
Clement, C., Ridd, M. J., Roberts, K., Santer, M., Boyle, R., Muller, I., …Shaw, A. R. (2020). Parents and GPs' understandings and beliefs about food allergy testing in children with eczema: Qualitative interview study within the Trial of Eczema allergy Screening Tests (TEST) feasibility trial. BMJ Open, 10(11), Article e041229. https://doi.org/10.1136/bmjopen-2020-041229

Aim To explore parent and general practitioner (GP) understanding and beliefs about food allergy testing for children with eczema. Design and setting Qualitative interview study in UK primary care within the Trial of Eczema allergy Screening Tests fe... Read More about Parents and GPs' understandings and beliefs about food allergy testing in children with eczema: Qualitative interview study within the Trial of Eczema allergy Screening Tests (TEST) feasibility trial.

Treatment decision-making among men with lower urinary tract symptoms: A qualitative study of men's experiences with recommendations for patient-centred practice (2020)
Journal Article
Selman, L. E., Clement, C., Ochieng, C. A., Lewis, A. L., Chapple, C., Abrams, P., …Horwood, J. (2021). Treatment decision-making among men with lower urinary tract symptoms: A qualitative study of men's experiences with recommendations for patient-centred practice. Neurourology and Urodynamics, 40(1), 201-210. https://doi.org/10.1002/nau.24533

Aims: To inform and guide patient-centred care for men with lower urinary tract symptoms (LUTS), by providing in-depth qualitative evidence regarding men's perspectives on treatment decision-making for LUTS. Methods: An interview study of men recruit... Read More about Treatment decision-making among men with lower urinary tract symptoms: A qualitative study of men's experiences with recommendations for patient-centred practice.