Outputs (112)

Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study (2017)
Journal Article

Aims Clinical decision rules (CDRs) can be applied in Emergency Departments (EDs) to optimise the use of computed tomography (CT) in children with head trauma. The National Emergency X- Radiography Utilisation Study II (NEXUS II) CDR, as amended for... Read More about Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study.

Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study (2017)
Journal Article

Aims Mild traumatic brain injury (TBI) in children is a major public health issue, yet there is wide variation in the way ‘mild’ TBI is defined in the literature and in guidelines. To date no study has prospectively detailed the proportion of childre... Read More about Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study.

Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study (2017)
Journal Article

Aims Traumatic cardiac arrest (TCA) is associated with high mortality and poor neurological outcomes. Several methods of confirming cardiac arrest are utilised including auscultation of heart sounds, palpation of pulses and echocardiography. We did a... Read More about Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study.

Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study (2017)
Journal Article

Aims Clinical decision rules (CDRs) can assist in determining the need for computed tomography (CT) in children with head injuries (HIs). We assessed the accuracy of 3 high quality CDRs (PECARN, CATCH and CHALICE) in a large prospective cohort of hea... Read More about Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study.

Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study (2017)
Journal Article

Aims While the majority of head injuries (HIs) in children are non-intentional, there is limited information on intentional HIs outside abusive head trauma. The objective of this study was to describe epidemiology, demographics and severity of intent... Read More about Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study.

Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study (2017)
Journal Article

Background Paediatric traumatic cardiac arrest (TCA) is associated with low survival and poor outcomes. The mechanisms that underlie TCA are different from medical cardiac arrest; the approach to treatment of TCA may therefore also need to differ to... Read More about Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study.

Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study (2017)
Journal Article

Background Traumatic cardiac arrest (TCA) in children has traditionally been described as having a poor outcome. Survival rates vary widely between studies with higher rates observed from mechanisms leading to a respiratory cause of TCA (e.g. drownin... Read More about Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study.

Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial (2017)
Journal Article

© The Author(s). 2017. Background: Convulsive status epilepticus (CSE) is the most common life-threatening neurological emergency in childhood. These children are also at risk of significant morbidity, with acute and chronic impact on the family and... Read More about Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial.

Ten concerns about blood pressure measurement and targets in paediatric sepsis (2016)
Journal Article

Current paediatric sepsis guidelines suggest that resuscitation is titrated against clinical markers of hypovolaemia and end organ perfusion [1], including blood pressure (BP), heart rate and capillary refill time (CRT). BP is used both as a defining... Read More about Ten concerns about blood pressure measurement and targets in paediatric sepsis.

A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock (2016)
Journal Article

Objectives & Background There is increasing evidence that fluid overload may be associated with harm in paediatric critical illness. Fluids in Shock (FiSH) is a combined feasibility and pilot randomised controlled trial (RCT) to determine if restric... Read More about A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock.