Outputs (10)

Factors that influence the administration of tranexamic acid (TXA) to trauma patients in prehospital settings: A systematic review (2023)
Journal Article

Objective: In the UK there are around 5400 deaths annually from injury. Tranexamic acid (TXA) prevents bleeding and has been shown to reduce trauma mortality. However, only 5% of UK major trauma patients who are at risk of haemorrhage receive prehosp... Read More about Factors that influence the administration of tranexamic acid (TXA) to trauma patients in prehospital settings: A systematic review.

Barriers and facilitators to the administration of prehospital tranexamic acid: A paramedic interview study using the theoretical domains framework (2021)
Journal Article

BACKGROUND: Tranexamic acid (TXA) is an antifibrinolytic drug used to prevent bleeding. It was introduced as an intervention for post-traumatic haemorrhage across emergency medical services (EMS) in the UK during 2012. However, despite strong evidenc... Read More about Barriers and facilitators to the administration of prehospital tranexamic acid: A paramedic interview study using the theoretical domains framework.

Staff stakeholder views on the role of UK paramedics in advance care planning for patients in their last year of life (2021)
Journal Article

Background: Early advance care planning has clear benefits for patients approaching the end of their life, yet many of those attended by UK paramedics do not have this planning in place. Aims: To explore staff stakeholder views on the role of UK p... Read More about Staff stakeholder views on the role of UK paramedics in advance care planning for patients in their last year of life.

Randomized trial of the i-gel supraglottic airway device versus tracheal intubation during out of hospital cardiac arrest (AIRWAYS-2): Patient outcomes at three and six months (2020)
Journal Article

© 2020 The Author(s) Aim: The AIRWAYS-2 cluster randomised controlled trial compared the i-gel supraglottic airway device (SGA) with tracheal intubation (TI) as the first advanced airway management (AAM) strategy used by Emergency Medical Service cli... Read More about Randomized trial of the i-gel supraglottic airway device versus tracheal intubation during out of hospital cardiac arrest (AIRWAYS-2): Patient outcomes at three and six months.

The experiences of EMS providers taking part in a large randomised trial of airway management during out of hospital cardiac arrest, and the impact on their views and practice. Results of a survey and telephone interviews (2020)
Journal Article

© 2020 Aims: To explore EMS experiences of participating in a large trial of airway management during out-of-hospital cardiac arrest (AIRWAYS-2), specifically to explore: 1. Any changes in views and practice as a result of trial participation. 2. Exp... Read More about The experiences of EMS providers taking part in a large randomised trial of airway management during out of hospital cardiac arrest, and the impact on their views and practice. Results of a survey and telephone interviews.

Cluster randomised comparison of the effectiveness of 100% oxygen versus titrated oxygen in patients with a sustained return of spontaneous circulation following out of hospital cardiac arrest: A feasibility study. PROXY: Post ROSC OXYgenation study (2019)
Journal Article

Background: Hyperoxia following out of hospital cardiac arrest (OHCA) is associated with a poor outcome. Animal data suggest the first hour post resuscitation may be the most important. In the UK the first hour usually occurs in the prehospital envir... Read More about Cluster randomised comparison of the effectiveness of 100% oxygen versus titrated oxygen in patients with a sustained return of spontaneous circulation following out of hospital cardiac arrest: A feasibility study. PROXY: Post ROSC OXYgenation study.

Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome the AIRWAYS-2 randomized clinical trial (2018)
Journal Article

© 2018 American Medical Association. All rights reserved. IMPORTANCE The optimal approach to airway management during out-of-hospital cardiac arrest is unknown. OBJECTIVE To determine whether a supraglottic airway device (SGA) is superior to tracheal... Read More about Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome the AIRWAYS-2 randomized clinical trial.

Data quality and 30-day survival for out-of-hospital cardiac arrest in the UK out-of-hospital cardiac arrest registry: A data linkage study (2017)
Journal Article

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. Objectives The Out-of-Hospital Cardiac Arrest Outcomes (OHCAO)... Read More about Data quality and 30-day survival for out-of-hospital cardiac arrest in the UK out-of-hospital cardiac arrest registry: A data linkage study.

Emergency medical service provider decision-making in out of hospital cardiac arrest: An exploratory study (2017)
Journal Article

© 2017 The Author(s). Background: There are approximately 60,000 out-of-hospital cardiac arrests (OHCA) in the United Kingdom (UK) each year. Within the UK there are well-established clinical practice guidelines that define when resuscitation should... Read More about Emergency medical service provider decision-making in out of hospital cardiac arrest: An exploratory study.

Design and implementation of the AIRWAYS-2 trial: A multi-centre cluster randomised controlled trial of the clinical and cost effectiveness of the i-gel supraglottic airway device versus tracheal intubation in the initial airway management of out of hospital cardiac arrest (2016)
Journal Article

© 2016 Health outcomes after out of hospital cardiac arrest (OHCA) are extremely poor, with only 7–9% of patients in the United Kingdom (UK) surviving to hospital discharge. Currently emergency medical services (EMS) use either tracheal intubation or... Read More about Design and implementation of the AIRWAYS-2 trial: A multi-centre cluster randomised controlled trial of the clinical and cost effectiveness of the i-gel supraglottic airway device versus tracheal intubation in the initial airway management of out of hospital cardiac arrest.