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Outputs (1353)

Using environmental and growth characteristics of plants to detect long-term changes in response to atmospheric pollution: Some examples from British beechwoods (2003)
Journal Article

This study uses the Ellenberg system of plant indicator values, along with Grime et al.'s plant growth strategy values, to investigate the nature of temporal changes in the composition of ground flora in two beechwoods in the Cotswolds region of the... Read More about Using environmental and growth characteristics of plants to detect long-term changes in response to atmospheric pollution: Some examples from British beechwoods.

DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines (2004)
Journal Article

This study used cDNA microarray technology to compare gene expression profiles in acute myeloblastic leukaemia (AML) with cDNA dot-blot and real time PCR analysis of cDNA transcripts to confirm array data. Patient AML marrow samples and AML cell line... Read More about DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines.

Use of bioluminescent Escherichia coli O157:H7 to study intra-protozoan survival of bacteria within Tetrahymena pyriformis (2003)
Journal Article

A method was developed that enabled real-time monitoring of the uptake and survival of bioluminescent Escherichia coli O157 within the freshwater ciliate Tetrahymena pyriformis. Constitutively bioluminescent E. coli O157 pLITE27 was cocultured with T... Read More about Use of bioluminescent Escherichia coli O157:H7 to study intra-protozoan survival of bacteria within Tetrahymena pyriformis.

Human mitochondrial branched chain aminotransferase: Structural basis for substrate specificity and role of redox active cysteines (2003)
Presentation / Conference Contribution

Crystal structures of the fold type IV pyridoxal phosphate (PLP)-dependent human mitochondrial branched chain aminotransferase (hBCATm) reaction intermediates have provided a structural explanation for the kinetically determined substrate specificity... Read More about Human mitochondrial branched chain aminotransferase: Structural basis for substrate specificity and role of redox active cysteines.

Uptake of 134Cs by four species from the Asteraceae and two varieties from the Chenopodiaceae grown in two types of Chinese soil (2003)
Journal Article

This study investigated the uptake of 134Cs by Lactuca sativa L., Silybum marianum Gaertn., Centaurea cyanus L., Carthamus tinctorius L. from the Asteraceae, and Beta vulgaris L. var. 'Lutiancai' and Beta vulgaris L. var. 'Hongtiancai' from the Cheno... Read More about Uptake of 134Cs by four species from the Asteraceae and two varieties from the Chenopodiaceae grown in two types of Chinese soil.

Syntheses and polymerizations of (E)-2-styrylfurans and an investigation of their electrorheological properties (2003)
Journal Article

Novel furan compounds, which incorporate phenyl rings separated by alkene spacers, have been synthesized. Chemical polymerization of these compounds yielded black brittle powders, suspensions of which were found to exhibit significant electrorheologi... Read More about Syntheses and polymerizations of (E)-2-styrylfurans and an investigation of their electrorheological properties.

Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate β-lyases, but turnover leads to inactivation (2003)
Journal Article

The mitochondrial and cytosolic branched-chain aminotransferases (BCATm and BCATc) are homodimers in the fold type IV class of pyridoxal 5′-phosphate-containing enzymes that also contains D-amino acid aminotransferase and 4-amino-4-deoxychorismate ly... Read More about Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate β-lyases, but turnover leads to inactivation.

Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries (2003)
Journal Article

A total of 94 European eels (Anguilla anguilla) were collected from five estuaries in the UK. The deconjugated metabolites of polycyclic aromatic hydrocarbons (PAHs) in the bile of the eels were separated using HPLC. Six PAH metabolites were identifi... Read More about Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries.

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation (2004)
Journal Article

Wt1 is a tumour suppressor gene, mutation of which is a cause of Wilms' tumour, a childhood renal nephroblastoma. Wt1 is expressed in a rich pattern during renal development suggesting that it acts at three stages: determination of the kidney area, t... Read More about Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.