Outputs (985)

A new approach to the determination of column overload characteristics in reversed-phase liquid chromatography (2009)
Journal Article

Column overloading is very common during the separations of basic analytes in analytical scale reversed-phase liquid chromatography (RPLC). Due to the complex interactions of ionic analytes with stationary and mobile phases, only a very small amount... Read More about A new approach to the determination of column overload characteristics in reversed-phase liquid chromatography.

The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment (2009)
Journal Article

It is widely accepted that alterations to cyclooxygenase-2 (COX-2) expression and the abundance of its enzymatic product prostaglandin E2 (PGE2) have key roles in influencing the development of colorectal cancer. Deregulation of the COX-2/PGE2 pathwa... Read More about The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment.

Cholinergic modulation of spontaneous activity in bladder strips from the diabetic rat: Effect of the mucosa (2009)
Journal Article

The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1 (2009)
Journal Article

The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1 (2009)
Journal Article

The mood stabilizing agents lithium chloride (LiCl) and sodium valproate (VPA) have recently gained interest as potential neuroprotective therapeutics. However, exploitation of these therapeutic applications is hindered by both a lack of molecular un... Read More about The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1.

Absence of mucosal immunity in the human upper respiratory tract to the commensal bacteria Neisseria lactamica but not pathogenic Neisseria meningitidis during the peak age of nasopharyngeal carriage (2009)
Journal Article

The normal flora that colonizes the mucosal epithelia has evolved diverse strategies to evade, modulate, or suppress the immune system and avoid clearance. Neisseria lactamica and Neisseria meningitidis are closely related obligate inhabitants of the... Read More about Absence of mucosal immunity in the human upper respiratory tract to the commensal bacteria Neisseria lactamica but not pathogenic Neisseria meningitidis during the peak age of nasopharyngeal carriage.

Δ 9 desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins (2009)
Journal Article

The aims of this study were to investigate the effect of feeding system and of supplementation of tannins (8.93% DM) on the relationship between intramuscular fat content, fatty acid composition and Δ 9 desaturase (Δ 9 d) protein expression in longis... Read More about Δ 9 desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins.

S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation (2009)
Journal Article

Specific proteins with reactive thiol(ate) groups are susceptible to nitric oxide (NO) modification, which can result in S-nitrosation, S-thiolation, or disulfide bond formation. In the present study the effect of NO modification on the functionality... Read More about S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation.

A microband lactate biosensor fabricated using a water-based screen-printed carbon ink (2009)
Journal Article

The present study demonstrated for the first time that screen-printed carbon microband electrodes fabricated from water-based ink can readily detect H2O2 and that the same ink, with the addition of lactate oxidase, can be used to construct microband... Read More about A microband lactate biosensor fabricated using a water-based screen-printed carbon ink.

Mesenchymal stem/stromal cell (MSC) response to chemotherapeutic damage (2009)
Presentation / Conference Contribution

S-nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and s-thiolation (2009)
Journal Article

Specific proteins with reactive thiol(ate) groups are susceptible to nitric oxide (NO) modification, which can result in S-nitrosation, S-thiolation, or disulfide bond formation. In the present study the effect of NO modification on the functionality... Read More about S-nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and s-thiolation.

Fabrication of microband glucose biosensors using a screen-printing water-based carbon ink and their application in serum analysis (2009)
Journal Article

Microband glucose biosensors were fabricated by screen-printing a water-based carbon ink formulation containing cobalt phthalocyanine redox mediator and glucose oxidase (GOD) enzyme, then insulating and sectioning through the thick (20 μm) film to ex... Read More about Fabrication of microband glucose biosensors using a screen-printing water-based carbon ink and their application in serum analysis.

Pollen generates nitric oxide and nitrite: a possible link to pollen-induced allergic responses (2009)
Journal Article

Reactive nitrogen species (RNS), such as nitric oxide (NO), are ubiquitous and diverse signalling molecules involved in a wide range of physiological and pathophysiological processes in both animals and plants. Nitrite, a metabolite of NO turnover, h... Read More about Pollen generates nitric oxide and nitrite: a possible link to pollen-induced allergic responses.

Reaction diffusion computers (2009)
Book

Reaction-diffusion controllers for robots (2009)
Book Chapter

Excitable systems, particularly spatially extended media, exhibit a wide variety of travelling patterns and different modes of interaction. The Belousov-Zhabo-tinsky [1] (BZ) reaction is the most well known and extensively studied example of non-line... Read More about Reaction-diffusion controllers for robots.

Sleepiness, countermeasures and the risk of motor vehicle accidents (2009)
Book Chapter

There are several factors that increase the risk of driver sleepiness and result in increased accident risk. Modern vehicle design enables the driver to travel at high speeds and for long distances in a comfortable and often sleep promoting driving... Read More about Sleepiness, countermeasures and the risk of motor vehicle accidents.

Preliminary investigations of the use of aromatherapy for treating mild to moderate insomnia (2009)
Presentation / Conference Contribution

Moderate exercise two hours before bedtime significantly improves sleep (2009)
Presentation / Conference Contribution

Rapeseed cytoplasm gives advantage in wild relatives and complicates genetically modified crop biocontainment (2009)
Journal Article

Biocontainment methods for genetically modified crops closest to commercial reality (chloroplast transformation, male sterility) would be compromised (in absolute terms) by seed-mediated gene flow leading to chloroplast capture. Even in these circums... Read More about Rapeseed cytoplasm gives advantage in wild relatives and complicates genetically modified crop biocontainment.

A review of techniques for monitoring the success of peatland restoration (2009)
Report

An important element of all peatland restoration projects is a programme of monitoring to check results and progress. Several peat project workshops identified a demand for technical guidance on monitoring techniques. So Natural England commissi... Read More about A review of techniques for monitoring the success of peatland restoration.