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Generation of red blood cells from stem cells: Achievements, opportunities and perspectives for malaria research (2022)
Journal Article
Satchwell, T. J. (2022). Generation of red blood cells from stem cells: Achievements, opportunities and perspectives for malaria research. Frontiers in Cellular and Infection Microbiology, 12, Article 1039520. https://doi.org/10.3389/fcimb.2022.1039520

Parasites of the genus Plasmodium that cause malaria survive within humans by invasion of, and proliferation within, the most abundant cell type in the body, the red blood cell. As obligate, intracellular parasites, interactions between parasite and... Read More about Generation of red blood cells from stem cells: Achievements, opportunities and perspectives for malaria research.

Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails (2022)
Journal Article
Williams, K., Szwalbe, A. J., de Mattos-Shipley, K. M. J., Bailey, A. M., Cox, R. J., & Willis, C. L. (2022). Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails. Natural Product Reports, 40(1), 128-157. https://doi.org/10.1039/d2np00041e

Covering: up to early 2022 Maleidrides are a family of polyketide-based dimeric natural products isolated from fungi. Many maleidrides possess significant bioactivities, making them attractive pharmaceutical or agrochemical lead compounds. Their unus... Read More about Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails.

Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens (2022)
Journal Article
Karamatic Crew, V., Tilley, L. A., Satchwell, T. J., AlSubhi, S. A., Jones, B., Spring, F. A., …Thornton, N. M. (2023). Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens. Blood, 141(2), 135-146. https://doi.org/10.1182/blood.2022016504

Despite the identification of the high-incidence red cell antigen Era nearly 40 years ago, the molecular background of this antigen, together with the other 2 members of the Er blood group collection, has yet to be elucidated. Whole exome and Sanger... Read More about Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens.

Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development (2022)
Journal Article
Petrova, Y. D., Zhao, J., Webster, G., Mullins, A. J., Williams, K., Alswat, A. S., …Mahenthiralingam, E. (2022). Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development. Microbial Biotechnology, 15(10), 2547-2561. https://doi.org/10.1111/1751-7915.14106

Burkholderia have potential as biocontrol agents because they encode diverse biosynthetic gene clusters (BGCs) for a range of antimicrobial metabolites. Given the opportunistic pathogenicity associated with Burkholderia species, heterologous BGC expr... Read More about Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development.

COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage (2022)
Journal Article
Turnbull, C. D., Allen, M., Appleby, J., Brown, R., Bryan, N., Cooper, A., …Nickol, A. (2022). COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage. Thorax, 77(8), 839-841. https://doi.org/10.1136/thoraxjnl-2021-218635

The COVID-19 pandemic changed continuous positive airway pressure (CPAP) setup pathways. We evaluated patients commenced on CPAP in 2019 (prepandemic) and 2020 (post-first UK wave). Face-to-face (F2F) setup numbers, with CPAP turned on, decreased fro... Read More about COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage.

In silico analyses of maleidride biosynthetic gene clusters (2022)
Journal Article
Williams, K., de Mattos-Shipley, K. M., Willis, C. L., & Bailey, A. M. (2022). In silico analyses of maleidride biosynthetic gene clusters. Fungal Biology and Biotechnology, 9(1), Article 2. https://doi.org/10.1186/s40694-022-00132-z

Maleidrides are a family of structurally related fungal natural products, many of which possess diverse, potent bioactivities. Previous identification of several maleidride biosynthetic gene clusters, and subsequent experimental work, has determined... Read More about In silico analyses of maleidride biosynthetic gene clusters.

Working from the inside out: Fostering intrinsic motivation and expanding our criteria for conservation success (2022)
Journal Article
Cardinal, C., Strubel, M. A., & Oxley, A. S. (2022). Working from the inside out: Fostering intrinsic motivation and expanding our criteria for conservation success. International Journal of Primatology, 43(6), 1177-1202. https://doi.org/10.1007/s10764-022-00280-4

Primatological research is often associated with understanding animals and their habitats, yet practical conservation depends entirely on human actions. This encompasses the activities of Indigenous and local people, conservationists, and NGOs workin... Read More about Working from the inside out: Fostering intrinsic motivation and expanding our criteria for conservation success.

Radioactivity in future phosphogypsum: New predictions based on estimates of ‘Peak P’ and rock phosphate resources (2022)
Journal Article
Willey, N., & Timbs, P. (2022). Radioactivity in future phosphogypsum: New predictions based on estimates of ‘Peak P’ and rock phosphate resources. Journal of Environmental Radioactivity, 244-245, Article 106828. https://doi.org/10.1016/j.jenvrad.2022.106828

Global food supplies currently depend on producing inorganic P fertilisers from a finite reserve of rock phosphate (RP). P fertilisers are themselves significant pollutants but their production from RP also leaves a phosphogypsum (PG) by-product that... Read More about Radioactivity in future phosphogypsum: New predictions based on estimates of ‘Peak P’ and rock phosphate resources.