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Outputs (982)

Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent (2013)
Journal Article

BACKGROUND: In this study, responses to fatty acid treatments in commonly used prostate cancer cell culture models and variability of gene expression between them were determined. MATERIALS AND METHODS: PC3, DU145, LNCaP, VCaP and PNT2 cells... Read More about Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent.

Human Homolog of Drosophila Ariadne (HHARI) is a marker of cellular proliferation associated with nuclear bodies (2012)
Journal Article

HHARI (also known as ARIH1) is an ubiquitin-protein ligase and is the cognate of the E2, UbcH7 (UBE2L3). To establish a functional role for HHARI in cellular proliferation processes, we performed a reverse genetics screen that identified n=86/522 (16... Read More about Human Homolog of Drosophila Ariadne (HHARI) is a marker of cellular proliferation associated with nuclear bodies.

A new approach to predicting environmental transfer of radionuclides to wildlife: A demonstration for freshwater fish and caesium (2013)
Journal Article

The application of the concentration ratio (CR) to predict radionuclide activity concentrations in wildlife from those in soil or water has become the widely accepted approach for environmental assessments. Recently both the ICRP and IAEA have produc... Read More about A new approach to predicting environmental transfer of radionuclides to wildlife: A demonstration for freshwater fish and caesium.

Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel - Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and wnt signalling defects (2013)
Journal Article

The ciliopathies are a group of heterogeneous diseases with considerable variations in phenotype for allelic conditions such as Meckel-Gruber syndrome (MKS) and Joubert syndrome (JBTS) even at the inter-individual level within families. In humans, mu... Read More about Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel - Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and wnt signalling defects.

Toward turing’s A-type unorganised machines in an unconventional substrate: A dynamic representation in compartmentalised excitable chemical media (2013)
Book Chapter

© Springer-Verlag Berlin Heidelberg 2013. Turing presented a general representation scheme by which to achieve artificial intelligence – unorganised machines. Significantly, these were a form of discrete dynamical system and yet such representations... Read More about Toward turing’s A-type unorganised machines in an unconventional substrate: A dynamic representation in compartmentalised excitable chemical media.

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: Implications for targeting adenoma stem cells with nsaids (2013)
Journal Article

Cyclooxygenase-2 is overexpressed in the majority of colorectal tumours leading to elevated levels of prostaglandin E2 (PGE2), promoting many hallmarks of cancer. Importantly, PGE2 is reported to enhance Wnt/β-catenin signalling in colorectal carcino... Read More about LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: Implications for targeting adenoma stem cells with nsaids.