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All Outputs (1026)

Emulating the delivery of sawtooth proton arc therapy plans on a cyclotron-based proton beam therapy system (2024)
Journal Article

Purpose: To evaluate and compare the deliverability of ‘sawtooth’ proton arc therapy (PAT) plans relative to static intensity modulated proton therapy (IMPT) at a cyclotron-based clinical facility.

Methods: The delivery of single and dual arc Saw... Read More about Emulating the delivery of sawtooth proton arc therapy plans on a cyclotron-based proton beam therapy system.

Mindfulness-based family psychoeducation intervention for caregivers of young adults with first-episode psychosis: Results at 9-month follow-up (2024)
Journal Article

Objectives: To investigate the effects of a mindfulness-based family psychoeducation (MBFPE) intervention on caregivers and the young adults with first-episode psychosis in mental health care.

Methods: Sixty-five caregivers were randomly assigned... Read More about Mindfulness-based family psychoeducation intervention for caregivers of young adults with first-episode psychosis: Results at 9-month follow-up.

Terrorism as an aesthetic signifier: The afterlives of terrorism discourse in Western reactions to wartime suffering (2024)
Journal Article

What are the legacies of the War on Terror? This paper seeks to answer this question through an analysis of vernacular uses of terrorism discourse in political commentary on the Ukraine War. The paper describes how the set of tropes, ideas and recurr... Read More about Terrorism as an aesthetic signifier: The afterlives of terrorism discourse in Western reactions to wartime suffering.

Sub-national transport bodies: Evaluation of initiatives to support local authority capacity and capability (2024)
Report

During 2021/22 the Department for Transport (DfT) made additional funding available to Sub-national Transport Bodies (STBs). The funding was to enable STBs to support their local authorities (LAs) in delivering transport policies in four priority are... Read More about Sub-national transport bodies: Evaluation of initiatives to support local authority capacity and capability.

Sexual and domestic violence enquiry: A national exploratory survey of asking and telling in sexual health services in the UK (2024)
Journal Article

Background
Gender-based violence in the form of domestic and sexual abuse represent a worldwide public health and civil rights issue. Healthcare and sexual health have a central role to play in prevention, particularly in the identification of sexua... Read More about Sexual and domestic violence enquiry: A national exploratory survey of asking and telling in sexual health services in the UK.

Experimental investigation of buckling and post-buckling behaviour of repaired composite laminates under in-plane shear loading (2024)
Journal Article

The performance of Ramped Scarf (RS) and Stepped Scarf (SS) repair schemes for highly loaded composite structures has been extensively studied under compressive, tensile, and flexural loadings. However, there is a lack of research on the buckling and... Read More about Experimental investigation of buckling and post-buckling behaviour of repaired composite laminates under in-plane shear loading.

Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways (2024)
Journal Article

Approximately 50% of poor prognosis neuroblastomas arise due to MYCN over-expression. We previously demonstrated that MYCN and PRMT5 proteins interact and PRMT5 knockdown led to apoptosis of MYCN amplified (MNA) neuroblastoma. Here we evaluate the hi... Read More about Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways.