Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis
(2022)
Journal Article
White, C., Rottschäfer, V., & Bridge, L. (2022). Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis. Journal of Theoretical Biology, 538, 110996. https://doi.org/10.1016/j.jtbi.2021.110996
The vascular endothelial growth factor (VEGF) receptor (VEGFR) system plays a role in cancer and many other diseases. It is widely accepted that VEGFR receptors dimerise in response to VEGF binding. However, analysis of these mechanisms and their imp... Read More about Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis.