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All Outputs (107)

An exploration of the collaborative processes of making theatre inspired by science (2012)
Journal Article
Dowell, E., & Weitkamp, E. (2012). An exploration of the collaborative processes of making theatre inspired by science. Public Understanding of Science, 21(7), 891-901. https://doi.org/10.1177/0963662510394278

This research examined the collaborative processes of making theatre inspired by science through the analysis of 16 semi-structured interviews with individual collaborators (eight theatre practitioners and eight scientists). Interviews explored exper... Read More about An exploration of the collaborative processes of making theatre inspired by science.

Banana production systems: Identification of alternative systems for more sustainable production (2012)
Journal Article
Bellamy, A. S. (2013). Banana production systems: Identification of alternative systems for more sustainable production. AMBIO: A Journal of the Human Environment, 42(3), 334-343. https://doi.org/10.1007/s13280-012-0341-y

Large-scale, monoculture production systems dependent on synthetic fertilizers and pesticides, increase yields, but are costly and have deleterious impacts on human health and the environment. This research investigates variations in banana productio... Read More about Banana production systems: Identification of alternative systems for more sustainable production.

A diagnostic apparatus for analysing a sample to diagnose disease (2012)
Patent
Ratcliffe, N. M., de Lacy Costello, B., Ewen, R., & Probert, C. (2012). A diagnostic apparatus for analysing a sample to diagnose disease. EP2502065 A2 (text from WO2011061308A2)

A diagnostic apparatus (10) for analysing a sample to diagnose disease, the apparatus (10) comprising: a separating element (16) for separating gas derived from the sample into component parts; a sensor arrangement (18) coupled to the separating elem... Read More about A diagnostic apparatus for analysing a sample to diagnose disease.

MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway (2012)
Journal Article
Brozzi, F., Lajus, S., Diraison, F., Rajatileka, S., Hayward, K., Regazzi, R., …Varadi, A. (2012). MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway. Molecular Biology of the Cell, 23(22), 4444-4455. https://doi.org/10.1091/mbc.E12-05-0369

Myosin- and Rab-interacting protein (MyRIP), which belongs to the protein kinase A (PKA)–anchoring family, is implicated in hormone secretion. However, its mechanism of action is not fully elucidated. Here we investigate the role of MyRIP in myosin V... Read More about MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway.

Evaluation of a silver-based electrocatalyst for the determination of hydrogen peroxide formed via enzymatic oxidation (2012)
Journal Article
Smyth, M. R., Gonzalez-Macia, L., & Killard, A. (2012). Evaluation of a silver-based electrocatalyst for the determination of hydrogen peroxide formed via enzymatic oxidation. Talanta, 99, 989-996. https://doi.org/10.1016/j.talanta.2012.07.082

Silver paste electrodes modified with lyotropic phases formed from dodecyl benzenesulphonic acid and KCl were used as the reductant in the determination of the hydrogen peroxide released from the enzymatic reaction of glucose oxidase with glucose and... Read More about Evaluation of a silver-based electrocatalyst for the determination of hydrogen peroxide formed via enzymatic oxidation.

Development of a novel, physiologically relevant cytotoxicity model: Application to the study of chemotherapeutic damage to mesenchymal stromal cells (2012)
Journal Article
May, J. E., Morse, H. R., Xu, J., & Donaldson, C. (2012). Development of a novel, physiologically relevant cytotoxicity model: Application to the study of chemotherapeutic damage to mesenchymal stromal cells. Toxicology and Applied Pharmacology, 263(3), 374-389. https://doi.org/10.1016/j.taap.2012.07.013

There is an increasing need for development of physiologically relevant in-vitro models for testing toxicity, however determining toxic effects of agents which undergo extensive hepatic metabolism can be particularly challenging. If a source of such... Read More about Development of a novel, physiologically relevant cytotoxicity model: Application to the study of chemotherapeutic damage to mesenchymal stromal cells.

The validation of a functional, isolated pig bladder model for physiological experimentation (2012)
Journal Article
Fry, C. H., Drake, M. J., Parsons, B. A., Gammie, A., & Vahabi, B. (2012). The validation of a functional, isolated pig bladder model for physiological experimentation. Frontiers in Pharmacology, 3 APR(52), 1-8. https://doi.org/10.3389/fphar.2012.00052

Characterizing the integrative physiology of the bladder requires whole organ preparations. The purpose of this study was to validate an isolated large animal (pig) bladder preparation, through arterial and intravesical drug administration, intravesi... Read More about The validation of a functional, isolated pig bladder model for physiological experimentation.

Investigation of the patterning of a lyotropic mixture onto silver paste electrodes via ink jet printing and its effect on the electroreduction of hydrogen peroxide (2012)
Presentation / Conference
Piano, M., Gonzalez-Macia, L., & Killard, A. (2012, September). Investigation of the patterning of a lyotropic mixture onto silver paste electrodes via ink jet printing and its effect on the electroreduction of hydrogen peroxide. Poster presented at Electrochem 2012, Dublin, Ireland

Detection of hydrogen peroxide is widely used in a range of applications, from pharmaceutical to clinical and food industry, as well as environmental analysis. Peroxide is generated during many biological reactions and its concentration can be stoich... Read More about Investigation of the patterning of a lyotropic mixture onto silver paste electrodes via ink jet printing and its effect on the electroreduction of hydrogen peroxide.

Development of a biosensor for HDL-cholesterol based on a novel electrocatalyst for hydrogen peroxide reduction (2012)
Presentation / Conference
Ahmadraji, T., Gonzalez-Macia, L., & Killard, A. (2012, September). Development of a biosensor for HDL-cholesterol based on a novel electrocatalyst for hydrogen peroxide reduction. Poster presented at Electrochem 2012, Dublin, Ireland

Cholesterol is synthesized in the liver and transported in the blood in association with low density lipoprotein (LDL-C) and high density lipoprotein (HDL-C). HDL-C is a modifiable risk for coronary heart disease. Its routine measurement is recommend... Read More about Development of a biosensor for HDL-cholesterol based on a novel electrocatalyst for hydrogen peroxide reduction.

Voltammetric behaviour of lead at a microband screen-printed carbon electrode and its trace determination in plants by stripping voltammetry (2012)
Presentation / Conference
Phillips, R., Honeychurch, K. C., Crew, A. P., Davies, R., Willey, N., & Hart, J. P. (2012, September). Voltammetric behaviour of lead at a microband screen-printed carbon electrode and its trace determination in plants by stripping voltammetry. Poster presented at Electrochem 2012: Electrochemical Horizons, Trinity College, Dublin

Application of a printed electrocatalyst for H2O2 to the development of biosensors (2012)
Presentation / Conference
Gonzalez-Macia, L., & Killard, A. (2012, September). Application of a printed electrocatalyst for H2O2 to the development of biosensors. Poster presented at Electrochem 2012, Dublin, Ireland

Many enzymatic reactions, e.g. the oxidation of glucose or cholesterol by glucose oxidase (GOx) or cholesterol oxidase (ChOx), respectively, in the presence of oxygen release hydrogen peroxide (H2O2) as an end-product. Therefore, the determination of... Read More about Application of a printed electrocatalyst for H2O2 to the development of biosensors.

Adrenomedullin receptors on human T cells are glucocorticoid-sensitive (2012)
Journal Article
Liverani, E., McLeod, J. D., & Paul, C. (2012). Adrenomedullin receptors on human T cells are glucocorticoid-sensitive. International Immunopharmacology, 14(1), 75-81. https://doi.org/10.1016/j.intimp.2012.06.011

Adrenomedullin (AM) is a novel vasodilatatory peptide which acts primarily through the calcitonin receptor-like receptor (CLR) in combination with either receptor-activity-modifying-protein (RAMP) 2 or 3 (forming receptors, AM 1 and AM2 respectively)... Read More about Adrenomedullin receptors on human T cells are glucocorticoid-sensitive.

Characterization of the Salmonella bacteriophage vB_SenS-Ent1 (2012)
Journal Article
Reynolds, D., Nelson, S., Turner, D., Hezwani, M., Nelson, S., Salisbury, V., & Reynolds, D. M. (2012). Characterization of the Salmonella bacteriophage vB_SenS-Ent1. Journal of General Virology, 93(PART 9), 2046-2056. https://doi.org/10.1099/vir.0.043331-0

The bacteriophage vB_SenS-Ent1 (Ent1) is a member of the family Siphoviridae of tailed bacteriophages and infects a broad range of serovars of the enteric pathogen Salmonella enterica. The virion particle is composed of an icosahedral head 64 nm in d... Read More about Characterization of the Salmonella bacteriophage vB_SenS-Ent1.

Exploring the ways environmental science is used and valued by policy-makers in Portugal: A case study (2012)
Journal Article
Sardo, M., & Weitkamp, E. (2012). Exploring the ways environmental science is used and valued by policy-makers in Portugal: A case study. Science Communication, 11(3), C05

Policymakers, researchers and the general public seem to agree that there is a need for evidence based policies. Here we report on a case study which explores environmental policy making at the national and local levels in one European country, Portu... Read More about Exploring the ways environmental science is used and valued by policy-makers in Portugal: A case study.

Characterization of the Salmonella bacteriophage vB_SenS-Ent1 (2012)
Journal Article
Turner, D., Hezwani, M., Nelson, S., Salisbury, V., & Reynolds, D. M. (2012). Characterization of the Salmonella bacteriophage vB_SenS-Ent1. Journal of General Virology, 93(9), 2046-2056. https://doi.org/10.1099/vir.0.043331-0

The bacteriophage vB_SenS-Ent1 (Ent1) is a member of the family Siphoviridae of tailed bacteriophages and infects a broad range of serovars of the enteric pathogen Salmonella enterica. The virion particle is composed of an icosahedral head 64 nm in d... Read More about Characterization of the Salmonella bacteriophage vB_SenS-Ent1.

Low dose ionizing radiation produces too few reactive oxygen species to directly affect antioxidant concentrations in cells (2012)
Journal Article
Smith, J. T., Willey, N., & Hancock, J. T. (2012). Low dose ionizing radiation produces too few reactive oxygen species to directly affect antioxidant concentrations in cells. Biology Letters, 8(4), 594-597. https://doi.org/10.1098/rsbl.2012.0150

It has been hypothesized that radiation-induced oxidative stress is the mechanism for a wide range of negative impacts on biota living in radioactively contaminated areas around Chernobyl. The present study tests this hypothesis mechanistically, for... Read More about Low dose ionizing radiation produces too few reactive oxygen species to directly affect antioxidant concentrations in cells.