Skip to main content

Research Repository

Advanced Search

Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches (2019)
Journal Article
Ellis, H. P., McInerney, C. E., Schrimpf, D., Sahm, F., Stupnikov, A., Wadsley, M., …Kurian, K. M. (2019). Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches. Journal of Oncology, 2019, Article 4878547. https://doi.org/10.1155/2019/4878547

© 2019 H. P. Ellis et al. Glioblastoma is the most common primary adult brain tumour, and despite optimal treatment, the median survival is 12-15 months. Patients with matched recurrent glioblastomas were investigated to try to find actionable mutati... Read More about Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches.

Experiential avoidance and cognitive fusion mediate the relationship between body evaluation and unhelpful body image coping strategies in individuals with visible differences (2019)
Journal Article
Zucchelli, F., White, P., & Williamson, H. (2020). Experiential avoidance and cognitive fusion mediate the relationship between body evaluation and unhelpful body image coping strategies in individuals with visible differences. Body Image, 32, 121-127. https://doi.org/10.1016/j.bodyim.2019.12.002

Psychological flexibility, the capacity to be open to any internal stimuli and act in accordance with valued ends, has been identified as an explanatory variable in how people cope with body concerns. The role of psychological flexibility is unexplor... Read More about Experiential avoidance and cognitive fusion mediate the relationship between body evaluation and unhelpful body image coping strategies in individuals with visible differences.

Characterising recovery from renal transplantation and live-related donation using cardiopulmonary exercise testing (2019)
Journal Article
Angell, J., Dodds, N., Darweish-Mednuik, A. M., Lewis, S., Pyke, M., Mitchell, D. C., …Tolchard, S. (2021). Characterising recovery from renal transplantation and live-related donation using cardiopulmonary exercise testing. Disability and Rehabilitation, 43(12), 1692-1698. https://doi.org/10.1080/09638288.2019.1674387

Background: An association between end-stage renal failure and exercise intolerance exists. Whether live kidney donation impacts on exercise tolerance is unknown. Here recovery post renal transplant and donation using cardiopulmonary exercise testing... Read More about Characterising recovery from renal transplantation and live-related donation using cardiopulmonary exercise testing.

Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study (2015)
Journal Article
White, P., Chambers, A. C., Bismohun, S. L., Davies, H., White, P., & Patil, A. V. (2015). Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study. International Journal of Surgery, 13, 207-210. https://doi.org/10.1016/j.ijsu.2014.11.041

© 2014 Surgical Associates Ltd. Appendicitis is a common clinical diagnosis aided by biochemical, haematological and radiological investigations. The role of some investigations, such as bilirubin, is controversial but could indicate complicated appe... Read More about Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study.

EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers (2015)
Journal Article
Kurian, K. M., DeSouza, R. M., Haynes, H. R., Faulkner, C., Palmer, A., Williams, H., …Kurian, K. M. (2015). EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers. British Journal of Neurosurgery, 29(1), 23-29. https://doi.org/10.3109/02688697.2014.950631

Copyright © 2014 The Neurosurgical Foundation. Introduction. EGFR and EGFRvIII analysis is of current interest because of new EGFRvIII vaccine trials opened in the UK. EGFR activation promotes cellular proliferation via activation of MAPK and PI3K-Ak... Read More about EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers.

Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection (2015)
Journal Article
Maskell, N. A., Zahan-Evans, N., Harvey, J. E., Medford, A. R., Clive, A. O., Edey, A. J., …Maskell, N. A. (2015). Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection. European Respiratory Journal, 46(2), 456-463. https://doi.org/10.1183/09031936.00147214

© ERS 2015. Pleural infection is increasing in incidence. Despite optimal medical management, up to 30% of patients will die or require surgery. Case reports suggest that irrigation of the pleural space with saline may be beneficial. A randomised con... Read More about Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection.

BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum (2015)
Journal Article
Faulkner, C., Ellis, H. P., Shaw, A., Penman, C., Palmer, A., Wragg, C., …Kurian, K. M. (2015). BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum. Journal of Neuropathology and Experimental Neurology, 74(9), 867-872. https://doi.org/10.1097/NEN.0000000000000226

Copyright © 2015 by the American Association of Neuropathologists, Inc. Pilocytic astrocytomas (PAs) are increasingly tested for KIAA1549-BRAF fusions. We used reverse transcription polymerase chain reaction for the 3 most common KIAA1549-BRAF fusion... Read More about BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.

The psychological well-being and appearance concerns of patients presenting with ptosis (2014)
Journal Article
White, P., Rumsey, N., Jenkinson, E., Richards, H. S., Jenkinson, E., Rumsey, N., …Harrad, R. A. (2014). The psychological well-being and appearance concerns of patients presenting with ptosis. Eye, 28(3), 296-302. https://doi.org/10.1038/eye.2013.264

PurposePtosis affects both the function and appearance of the eyes and face, because of drooping of the eyelids. Previous research has focused on functional impairment; however, similar appearance altering eye conditions have been demonstrated to hav... Read More about The psychological well-being and appearance concerns of patients presenting with ptosis.

Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery (2014)
Journal Article
Harrison, O. J., Smart, N. J., White, P., Brigic, A., Carlisle, E. R., Allison, A. S., …Francis, N. K. (2014). Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery. Journal- Society of Laparoendoscopic Surgeons, 18(2), 265-272. https://doi.org/10.4293/108680813X13753907291918

Background and Objectives: Combining laparoscopy and enhanced recovery provides benefit to short-term outcomes after colorectal surgery. Advances in training and techniques have allowed surgeons to operate on cases that are technically challenging an... Read More about Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery.

Randomized clinical trial of local anesthetic versus a combination of local anesthetic with self-hypnosis in the management of pediatric procedure-related pain (2006)
Journal Article
Liossi, C., White, P., & Hatira, P. (2006). Randomized clinical trial of local anesthetic versus a combination of local anesthetic with self-hypnosis in the management of pediatric procedure-related pain. Health Psychology, 25(3), 307-315. https://doi.org/10.1037/0278-6133.25.3.307

A prospective controlled trial was conducted to compare the efficacy of an analgesic cream (eutectic mixture of local anesthetics, or EMLA) with a combination of EMLA with hypnosis in the relief of lumbar puncture-induced pain and anxiety in 45 pedia... Read More about Randomized clinical trial of local anesthetic versus a combination of local anesthetic with self-hypnosis in the management of pediatric procedure-related pain.

Psychosocial outcomes derived from an acid burned population in Bangladesh, and comparison with Western norms (2006)
Journal Article
Salmanta, S., Mannan, A., Ghani, S., Clarke, A., White, P., & Butler, P. E. (2006). Psychosocial outcomes derived from an acid burned population in Bangladesh, and comparison with Western norms. Burns, 32(2), 235-241. https://doi.org/10.1016/j.burns.2005.08.027

Assault by acid burns typically results in severe disfigurement, yet the psychosocial impact of this injury is so far unreported. This study provides the first empirical data using standardised assessment scales, from 44 acid burns survivors in Bangl... Read More about Psychosocial outcomes derived from an acid burned population in Bangladesh, and comparison with Western norms.

Altered body image: Appearance-related concerns of people with visible disfigurement (2004)
Journal Article
Garlick, W., Wyn-Williams, M., Rumsey, N., Clarke, A., & White, P. (2004). Altered body image: Appearance-related concerns of people with visible disfigurement. Journal of Advanced Nursing, 48(5), 443-453. https://doi.org/10.1111/j.1365-2648.2004.03227.x

Aim. The aim of this paper is to report a study to establish the extent and type of psychosocial needs of outpatients attending for treatment of a wide range of disfiguring conditions. Background. Visible disfigurements can be associated with extensi... Read More about Altered body image: Appearance-related concerns of people with visible disfigurement.

Building better nurse scheduling algorithms (2004)
Journal Article
Aickelin, U., & White, P. (2004). Building better nurse scheduling algorithms. Annals of Operations Research, 128(1-4), 159-177. https://doi.org/10.1023/B%3AANOR.0000019103.31340.a6

The aim of this research is twofold: Firstly, to model and solve a complex nurse scheduling problem with an integer programming formulation and evolutionary algorithms. Secondly, to detail a novel statistical method of comparing and hence build bette... Read More about Building better nurse scheduling algorithms.

Exploring the psychosocial concerns of out-patients with disfiguring conditions (2003)
Journal Article
Rumsey, N., Clarke, A., & White, P. (2003). Exploring the psychosocial concerns of out-patients with disfiguring conditions. Journal of Wound Care, 12(7), 247-252

Objective: This study was undertaken to establish the extent and type of psychosocial need in outpatients attending for treatment for a variety of disfiguring conditions. Method: A total of 220 outpatients receiving treatment for burns, skin condit... Read More about Exploring the psychosocial concerns of out-patients with disfiguring conditions.

Investigating the appearance-related concerns of people with hand injuries (2003)
Journal Article
Rumsey, N., Clarke, A., White, P., & Hooper, E. (2003). Investigating the appearance-related concerns of people with hand injuries. British Journal of Hand Therapy, 8(2), 57-61

An investigation of the appearance-related concerns of patients with disfiguring hand conditions was carried out in two out-patient clinics. A considerable proportion of the 122 respondents were experiencing psychosocial problems including anxiety, d... Read More about Investigating the appearance-related concerns of people with hand injuries.

Efficacy of clinical hypnosis in the enhancement of quality of life of terminally ill cancer patients (2001)
Journal Article
Liossi, C., & White, P. (2001). Efficacy of clinical hypnosis in the enhancement of quality of life of terminally ill cancer patients. Contemporary Hypnosis, 18(3), 145-160. https://doi.org/10.1002/ch.228

The fact that terminal cancer patients experience considerable psychological distress is now undisputed, but the effectiveness of psychological treatments in relieving this suffering is less clear. The aim of the present research was to evaluate the... Read More about Efficacy of clinical hypnosis in the enhancement of quality of life of terminally ill cancer patients.

An inverse normal transformation solution for the comparison of two samples that contain both paired observations and independent observations
Journal Article
Derrick, B., White, P., & Toher, D. An inverse normal transformation solution for the comparison of two samples that contain both paired observations and independent observations

Inverse normal transformations applied to the partially overlapping samples t-tests by Derrick et.al. (2017) are considered for their Type I error robustness and power. The inverse normal transformation solutions proposed in this paper are shown to m... Read More about An inverse normal transformation solution for the comparison of two samples that contain both paired observations and independent observations.