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ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia? (2020)
Journal Article
Vahabi, B., Jabr, R., Fry, C., McCloskey, K., Everaert, K., Agudelo, C. W., …Weiss, J. P. (in press). ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?. Neurourology and Urodynamics, https://doi.org/10.1002/nau.24274

© 2020 Wiley Periodicals, Inc. Introduction: The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT). Objectives: The objectives of the 2019 NTT were as follows: (... Read More about ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?.

Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches (2019)
Journal Article
Ellis, H. P., McInerney, C. E., Schrimpf, D., Sahm, F., Stupnikov, A., Wadsley, M., …Kurian, K. M. (2019). Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches. Journal of Oncology, 2019, https://doi.org/10.1155/2019/4878547

© 2019 H. P. Ellis et al. Glioblastoma is the most common primary adult brain tumour, and despite optimal treatment, the median survival is 12-15 months. Patients with matched recurrent glioblastomas were investigated to try to find actionable mutati... Read More about Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches.

Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis (2019)
Journal Article
Akpiri, R. U., Hodges, N. J., & Konya, R. S. (2020). Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis. Journal of Marine Science, 2(1), https://doi.org/10.30564/jms.v2i1.1070

Aluminium is the most abundant element in the earth crust, and has no known biological function. However, it is an established neurotoxicant in its trivalent oxidation state, with exposure resulting in neurodegenerative diseases like Parkinson’s dise... Read More about Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis.

Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa (2019)
Journal Article
Elcocks, E., Spencer‐Phillips, P., & Adukwu, E. (2020). Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa. Journal of Applied Microbiology, 128(4), 1025-1037. https://doi.org/10.1111/jam.14538

AIMS: This study aimed to identify the most effective antimicrobial from a selection of essential oils and investigate its bactericidal properties against Ps. aeruginosa. METHODS AND RESULTS: The disc diffusion assay and minimal inhibitory/bacte... Read More about Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa.

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). (2019)
Journal Article
Gynn, L. E., Anderson, E., Robinson, G. M., Wexler, S. A., Upstill-Goddard, G., Cox, C., …Morgan, R. G. (2019). Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). Blood, 134(Supplement 1), 2492. https://doi.org/10.1182/blood-2019-122891

Mesenchymal stromal cells (MSC) are known to protect leukemic cells from drug-induced toxicity within the bone marrow (BM) niche, however, less is known about leukemic impact on supportive MSC. The nucleoside-analogue, cytarabine (Ara-C), is a front-... Read More about Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)..

Political Affiliation and Population Views on the Role of Family and Volunteer Carers to Supplement State Provision in End of Life Care in England (2019)
Presentation / Conference
Verne, J., Tapp, A., Nancarrow, C., Warren, S., & Morey, Y. (2019, May). Political Affiliation and Population Views on the Role of Family and Volunteer Carers to Supplement State Provision in End of Life Care in England. Poster presented at 16th World Congress of the European Association for Palliative Care, Berlin, Germany

Political affiliation and population views on the role of family and volunteer carers to supplement state provision in end of life care in England Alan Tapp, Clive Nancarrow, Yvette Morey, Stella Warren, Julia Verne Background: In England politicia... Read More about Political Affiliation and Population Views on the Role of Family and Volunteer Carers to Supplement State Provision in End of Life Care in England.

One in Ten Older Adults Aged 45 Years Report Having No-one to Turn to for Help at the End of Life Apart from Professionals - Who are they? (2019)
Presentation / Conference
Verne, J., Tapp, A., Nancarrow, C., Morey, Y., & Warren, S. (2019, May). One in Ten Older Adults Aged 45 Years Report Having No-one to Turn to for Help at the End of Life Apart from Professionals - Who are they?. Poster presented at 16th World Congress of the European Association for Palliative Care (EPAC), Berlin, Germany

- Background: There is increased interest in the impact of living alone and loneliness on people’s wellbeing at the end of life and practicality of providing care, especially at home. In a nationally representative sample of 3,590 people aged >45 yea... Read More about One in Ten Older Adults Aged 45 Years Report Having No-one to Turn to for Help at the End of Life Apart from Professionals - Who are they?.

One in Ten Older Adults Aged 45 Years Report Having No-one to Turn to for Help at the End of Life Apart from Professionals - Who are they? (2019)
Presentation / Conference
Verne, J., Tapp, A., Nancarrow, C., Morey, Y., & Warren, S. (2019, May). One in Ten Older Adults Aged 45 Years Report Having No-one to Turn to for Help at the End of Life Apart from Professionals - Who are they?. Poster presented at 16th EAPC World Congress, Berlin, Germany

- Background: There is increased interest in the impact of living alone and loneliness on people’s wellbeing at the end of life and practicality of providing care, especially at home. In a nationally representative sample of 3,590 people aged >45 yea... Read More about One in Ten Older Adults Aged 45 Years Report Having No-one to Turn to for Help at the End of Life Apart from Professionals - Who are they?.

The application of gene expression profiling in predictions of occult lymph node metastasis in colorectal cancer patients (2018)
Journal Article
Peyravian, N., Larki, P., Gharib, E., Nazemalhosseini-Mojarad, E., Anaraki, F., Young, C., …Zali, M. (2018). The application of gene expression profiling in predictions of occult lymph node metastasis in colorectal cancer patients. Biomedicines, 6(1), 27. https://doi.org/10.3390/biomedicines6010027

A key factor in determining the likely outcome for a patient with colorectal cancer is whether or not the tumour has metastasised to the lymph nodes-information which is also important in assessing any possibilities of lymph node resection so as to i... Read More about The application of gene expression profiling in predictions of occult lymph node metastasis in colorectal cancer patients.

GJA4/connexin 37 mutations correlate with secondary lymphedema following surgery in breast cancer patients (2018)
Journal Article
Hadizadeh, M., Mohaddes Ardebili, S., Salehi, M., Young, C., Mokarian, F., McClellan, J., …Bonab, M. A. (2018). GJA4/connexin 37 mutations correlate with secondary lymphedema following surgery in breast cancer patients. Biomedicines, 6(1), 23. https://doi.org/10.3390/biomedicines6010023

Lymphedema is a condition resulting from mutations in various genes essential for lymphatic development and function, which leads to obstruction of the lymphatic system. Secondary lymphedema is a progressive and incurable condition, most often manife... Read More about GJA4/connexin 37 mutations correlate with secondary lymphedema following surgery in breast cancer patients.

Rapid in vitro testing and characterization of resistance to chemotherapeutic agents daunorubicin and cytarabine in acute myeloid leukaemia (2017)
Journal Article
May, J., Steven, J., Taylor, A., Dean, S., & Anderson, E. (2017). Rapid in vitro testing and characterization of resistance to chemotherapeutic agents daunorubicin and cytarabine in acute myeloid leukaemia. Mutagenesis, 32(6), 627. https://doi.org/10.1093/mutage/gex033

Treatment success in leukaemia is impacted by patient resistance to chemotherapy including cytarabine (ara-C) and the anthracycline daunorubicin (DNR) requiring rapid pre-screening testing. DNR is converted to daunorubicinol (DNRol) by carbonyl reduc... Read More about Rapid in vitro testing and characterization of resistance to chemotherapeutic agents daunorubicin and cytarabine in acute myeloid leukaemia.

Development of a 2D leukaemia-stroma model for analyses of chemo-toxicity protection using a novel bacterial bioluminescent biosensor (2017)
Journal Article
Gynn, L., May, J., Anderson, E., & Robinson, G. (2017). Development of a 2D leukaemia-stroma model for analyses of chemo-toxicity protection using a novel bacterial bioluminescent biosensor. Mutagenesis, 32(6), 619. https://doi.org/10.1093/mutage/gex033

This study aimed to develop a 2D leukaemia-stroma model of the bone marrow for analysis of stromal-mediated chemo-protection; known to contribute to chemotherapy resistance. The model must facilitate integration of a bioluminescent biosensor HA1 for... Read More about Development of a 2D leukaemia-stroma model for analyses of chemo-toxicity protection using a novel bacterial bioluminescent biosensor.

Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS) (2017)
Journal Article
May, J., Robinson, G., Thorn, R., & Reynolds, D. (2017). Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS). Mutagenesis, 32(6), 622-623. https://doi.org/10.1093/mutage/gex033

Electrochemically activated solutions (ECAS) are of interest as potential disinfectants due to high biocidal activity against many microorganisms. They are widely used clinically in some countries (decontamination of surgical instruments and wounds),... Read More about Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS).

An old dog and new tricks: Genetic analysis of a Tudor dog recovered from the Mary Rose wreck (2014)
Journal Article
Zouganelis, G. D., Ogden, R., Nahar, N., Runfola, V., Bonab, M., Ardalan, A., …Scarlett, G. (2014). An old dog and new tricks: Genetic analysis of a Tudor dog recovered from the Mary Rose wreck. Forensic Science International, 245, 51-57. https://doi.org/10.1016/j.forsciint.2014.10.001

© 2014 Elsevier Ireland Ltd. The Tudor warship the Mary Rose sank in the Solent waters between Portsmouth and the Isle of Wight on the 19th of July 1545, whilst engaging a French invasion fleet. The ship was rediscovered in 1971 and between 1979 and... Read More about An old dog and new tricks: Genetic analysis of a Tudor dog recovered from the Mary Rose wreck.

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations (2009)
Journal Article
Hiby, S. E., Ashrafian-Bonab, M., Farrell, L., Single, R. M., Balloux, F., Carrington, M., & Moffett, A. (2010). Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations. Immunogenetics, 62(2), 65-73. https://doi.org/10.1007/s00251-009-0408-5

Killer cell immunoglobulin-like receptors (KIR) gene frequencies vary between populations and contribute to functional variation in immune responses to viruses, autoimmunity and reproductive success. This study describes the frequency distribution of... Read More about Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.


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