This paper describes the design and development of a novel electrochemical biosensor for measuring glycerol in wine. Our initial detailed studies were aimed at deducing the optimum conditions for biosensor operation by conducting hydrodynamic voltamm... Read More about Development of a disposable, amperometric glycerol biosensor based on a screen-printed carbon electrode, modified with the electrocatalyst meldolas blue, coated with glycerol dehydrogenase and NAD+: Application to the analysis of wine quality.
Outputs (18)
Choices made to study STEM subjects determine both the level of STEM skills in the population and the numbers of students with the necessary skills to continue studying STEM subjects at higher education. The aim of this research was to explore curren... Read More about What are the challenges in progression, retention and achievement in A-level chemistry in Further Education colleges in England?.
Haemostatic disorders cause excessive bleeding and clotting and result in high morbidity and mortality worldwide, but especially in low-income areas which often lack suitable facilities and expertise for affordable diagnosis and treatment. Simple and... Read More about Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders.
Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids (2023)
Journal Article
This paper describes, for the first time, the development of a novel trilinolein biosensor based on the immobilisation of lipase and lipoxygenase (LOX) onto a cobalt phthalocyanine screen-printed carbon electrode (CoPC-SPCE) in conjunction with amper... Read More about Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids.
A non-faradaic impedimetric biosensor for monitoring of caspase 9 in mammalian cell culture (2023)
Journal Article
Lower yields and poorer quality of biopharmaceutical products result from cell death in bioreactors. Such cell death is commonly associated with programmed cell death or apoptosis. During apoptosis, caspases are activated and cause a cascade of event... Read More about A non-faradaic impedimetric biosensor for monitoring of caspase 9 in mammalian cell culture.
Eliminating transition state calculations for faster and more accurate reactivity prediction in Sulfa-Michael additions relevant to human health and the environment (2022)
Journal Article
Fast and accurate computational approaches to predicting reactivity in sulfa-Michael additions are required for high-throughput screening in toxicology (e.g., predicting excess aquatic toxicity and skin sensitization), chemical synthesis, covalent dr... Read More about Eliminating transition state calculations for faster and more accurate reactivity prediction in Sulfa-Michael additions relevant to human health and the environment.
The message on the bottle: Rethinking plastic labelling to better encourage sustainable use (2022)
Journal Article
Plastic pollution continues to worsen globally in volume and complexity. The complexity in plastic production, use and disposal is significant, highlighting the importance of clear communication to consumers. Yet despite this, poor plastic labelling... Read More about The message on the bottle: Rethinking plastic labelling to better encourage sustainable use.
Machine learning activation energies of chemical reactions (2021)
Journal Article
Application of machine learning (ML) to the prediction of reaction activation barriers is a new and exciting field for these algorithms. The works covered here are specifically those in which ML is trained to predict the activation energies of homoge... Read More about Machine learning activation energies of chemical reactions.
Propofol detection for monitoring of intravenous anaesthesia: A review (2021)
Journal Article
This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared... Read More about Propofol detection for monitoring of intravenous anaesthesia: A review.
Reactivity prediction in aza-Michael additions without transition state calculations: The Ames test for mutagenicity (2020)
Journal Article
Animal testing remains a contentious ethical issue in predictive toxicology. Thus, a fast, versatile, low-cost quantum chemical model is presented for predicting the risk of Ames mutagenicity in a series of 1,4 Michael acceptor type compounds. This f... Read More about Reactivity prediction in aza-Michael additions without transition state calculations: The Ames test for mutagenicity.
Density functional theory in the prediction of mutagenicity: A perspective (2020)
Journal Article
As a field, computational toxicology is concerned with using in silico models to predict and understand the origins of toxicity. It is fast, relatively inexpensive, and avoids the ethical conundrum of using animals in scientific experimentation. In t... Read More about Density functional theory in the prediction of mutagenicity: A perspective.
Screen-printed carbon based biosensors and their applications in agri-food safety (2020)
Journal Article
This review focuses on the ways in which screen-printed carbon electrodes have been tailored with different biorecognition elements, including enzymes, antibodies, and aptamers, often with other modifiers, such as mediators and nanoparticles, to prod... Read More about Screen-printed carbon based biosensors and their applications in agri-food safety.
The Physics of Print (2020)
Presentation / Conference Contribution
Comparisons of different force fields in conformational analysis and searching of organic molecules: A review (2020)
Journal Article
This review aims to examine literature where different force fields are compared by their performances in conformational analysis and searching of organic molecules. Conformational analysis studies are those where energies and/or geometries of confor... Read More about Comparisons of different force fields in conformational analysis and searching of organic molecules: A review.
The invention relates to the field of sensors for detecting volatile compounds. The sensor of the present invention for detecting volatile compounds comprises: a film of metal oxide; a heater configured to provide heat energy to the film of metal oxi... Read More about Sensors for determining volatile compounds based on electrical conductivity and cataluminescence measurements of metal oxide films.
Incommensurate Compositions (2018)
Digital Artefact
An output from a collaborative project with Architects and Crystallographers from Cardiff University to explore creative opportunities within crystallographic data-sets and modelling algorithms.
These compositions are made with a software tool, co... Read More about Incommensurate Compositions.
Composing with crystallography (2018)
Exhibition / Performance
Collaborative project with Architects and Crystallographers from Cardiff University to explore creative opportunities within crystallographic data-sets and modelling algorithms. This composition research developed and extended their Leverhulme funded... Read More about Composing with crystallography.
Surface water characteristics and trace metals level of the Bonny/New Calabar River Estuary, Niger Delta, Nigeria (2015)
Journal Article
Surface water samples from three stations in the Bonny/New Calabar River Estuary were analyzed for the physicochemical characteristics and trace metal level in 2011 and 2012, respectively. Results show pH ranged from 7.56 to 7.88mg/L; conductivity, 3... Read More about Surface water characteristics and trace metals level of the Bonny/New Calabar River Estuary, Niger Delta, Nigeria.