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Acetyl-CoA carboxylase and stearoyl-CoA desaturase protein expression in subcutaneous adipose tissue is reduced in pigs selected for decreased backfat thickness at constant intramuscular fat content (2009)
Journal Article
Cánovas, A., Estany, J., Tor, M., Pena, R. N., & Doran, O. (2009). Acetyl-CoA carboxylase and stearoyl-CoA desaturase protein expression in subcutaneous adipose tissue is reduced in pigs selected for decreased backfat thickness at constant intramuscular fat content. Journal of Animal Science, 87(12), 3905-3914. https://doi.org/10.2527/jas.2009-2091

The objectives of this study were 1) to determine whether selection toward less subcutaneous fat thickness at constant intramuscular fat content in pigs is related to tissue-specific changes in the expression of lipogenic enzymes acetyl-CoA carboxyla... Read More about Acetyl-CoA carboxylase and stearoyl-CoA desaturase protein expression in subcutaneous adipose tissue is reduced in pigs selected for decreased backfat thickness at constant intramuscular fat content.

Effect of breed on fatty acid composition and stearoyl-CoA desaturase protein expression in the Semimembranosus muscle and subcutaneous adipose tissue of cattle (2009)
Journal Article
Dance, L. J., Matthews, K. R., & Doran, O. (2009). Effect of breed on fatty acid composition and stearoyl-CoA desaturase protein expression in the Semimembranosus muscle and subcutaneous adipose tissue of cattle. Livestock Science, 125(2-3), 291-297. https://doi.org/10.1016/j.livsci.2009.05.009

The present study investigated (i) the effect of breed on the expression of stearoyl-CoA desaturase (SCD) protein and fatty acid composition in Semimembranosus muscle and subcutaneous adipose tissue of beef cattle and (ii) the relationship between SC... Read More about Effect of breed on fatty acid composition and stearoyl-CoA desaturase protein expression in the Semimembranosus muscle and subcutaneous adipose tissue of cattle.

The ALCASDE project and WP1 tasks (2009)
Presentation / Conference
Doran, O. (2009, October). The ALCASDE project and WP1 tasks. Presented at Boar Taint Detection Workshop, Bologna, Italy

Effect of supplementation of the maternal diet with fish oil or linseed oil on fatty-acid composition and expression of δ5- and δ6-desaturase in tissues of female piglets (2009)
Journal Article
Missotten, J., De Smet, S., Raes, K., & Doran, O. (2009). Effect of supplementation of the maternal diet with fish oil or linseed oil on fatty-acid composition and expression of δ5- and δ6-desaturase in tissues of female piglets. animal, 3(8), 1196-1204. https://doi.org/10.1017/S1751731109004455

The present study investigated whether enrichment of the pig maternal diet with n-3 polyunsaturated fatty acids (PUFA) affects the fatty-acid composition of female piglets via enhancing of expression of the lipogenic enzymes 5-desaturase (5d) and 6-d... Read More about Effect of supplementation of the maternal diet with fish oil or linseed oil on fatty-acid composition and expression of δ5- and δ6-desaturase in tissues of female piglets.

Delta 9-desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins (2009)
Journal Article
Vasta, V., Priolo, A., Scerra, M., Hallett, K., Wood, J., & Doran, O. (2009). Delta 9-desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins. Meat Science, 82(3), 357-364. https://doi.org/10.1016/j.meatsci.2009.02.007

Δ 9 desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins (2009)
Journal Article
Wood, J. D., Hallett, K. G., Vasta, V., Priolo, A., Scerra, M., & Doran, O. (2009). Δ 9 desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins. Meat Science, 82(3), 357-364. https://doi.org/10.1016/j.meatsci.2009.02.007

The aims of this study were to investigate the effect of feeding system and of supplementation of tannins (8.93% DM) on the relationship between intramuscular fat content, fatty acid composition and Δ 9 desaturase (Δ 9 d) protein expression in longis... Read More about Δ 9 desaturase protein expression and fatty acid composition of longissimus dorsi muscle in lambs fed green herbage or concentrate with or without added tannins.

Genetic test for food quality (2009)
Presentation / Conference
Doran, O. (2009, January). Genetic test for food quality. Paper presented at Abstracts of Lectures and Posters of International Conference Repid Methods Europe 2009, Noordwijkerhout, The Netherlands

Effect of sex steroids on expression of sulfotransferase 2B1 immunoreactive protein in primary cultured porcine hepatocytes (2008)
Journal Article
Panella-Riera, N., Moe, M., Grindflek, E., Oliver, M. A., Wood, J. D., & Doran, O. (2008). Effect of sex steroids on expression of sulfotransferase 2B1 immunoreactive protein in primary cultured porcine hepatocytes. Livestock Science, 118(3), 223-230. https://doi.org/10.1016/j.livsci.2008.01.021

An excessive accumulation of androstenone (5α-androst-16-en-3-one) in pig adipose tissue is one of the two major contributors to the phenomenon of boar taint. High levels of adipose tissue androstenone have been related to a low rate of hepatic andro... Read More about Effect of sex steroids on expression of sulfotransferase 2B1 immunoreactive protein in primary cultured porcine hepatocytes.

ALCASDE project: Study on the improved methods for animal-friendly production, in particular on alternatives to the castration of pigs and on alternatives to the dehorming of cattle (2008)
Presentation / Conference
Oliver, M. A., Mirabito, L., Vessier, I., Thomas, C., Bonneua, M., Doran, O., …Pentelescu, O. N. (2008, August). ALCASDE project: Study on the improved methods for animal-friendly production, in particular on alternatives to the castration of pigs and on alternatives to the dehorming of cattle. Paper presented at 59th EAAP meeting, Vilnius, Lithuania

Effect of testosterone, estrone sulphate and androstenone on 3β-hydroxysteroid dehydrogenase protein expression in primary cultured hepatocytes (2008)
Journal Article
Nicolau-Solano, S. I., & Doran, O. (2008). Effect of testosterone, estrone sulphate and androstenone on 3β-hydroxysteroid dehydrogenase protein expression in primary cultured hepatocytes. Livestock Science, 114(2-3), 202-210. https://doi.org/10.1016/j.livsci.2007.05.001

Androstenone (5α-androst-16-en-3-one) is a steroid pheromone, excessive accumulation of which in pig adipose tissue contributes to the phenomenon of "boar taint". The incidence of boar taint increases with age and weight of entire male pigs. One of t... Read More about Effect of testosterone, estrone sulphate and androstenone on 3β-hydroxysteroid dehydrogenase protein expression in primary cultured hepatocytes.

Regulation of CYP2A6 protein expression by skatole, indole, and testicular steroids in primary cultured pig hepatocytes (2008)
Journal Article
Wood, J. D., Chen, G., Cue, R. A., Lundstrom, K., & Doran, O. (2008). Regulation of CYP2A6 protein expression by skatole, indole, and testicular steroids in primary cultured pig hepatocytes. Drug Metabolism and Disposition, 36(1), 56-60. https://doi.org/10.1124/dmd.107.017285

CYP2A6 is one of the enzymes involved in the hepatic metabolism of a naturally produced compound, skatole, in the pig. Low CYP2A6 activity has been linked to excessive accumulation of skatole in pig adipose tissue and development of the phenomenon "b... Read More about Regulation of CYP2A6 protein expression by skatole, indole, and testicular steroids in primary cultured pig hepatocytes.

Expression of 3β-hydroxysteroid dehydrogenase, cytochrome P450-c17, and sulfotransferase 2B1 proteins in liver and testis of pigs of two breeds: Relationship with adipose tissue androstenone concentration (2007)
Journal Article
Moe, M., Moe, E., Grindflek, E., & Doran (nee Udovikova), O. (2007). Expression of 3β-hydroxysteroid dehydrogenase, cytochrome P450-c17, and sulfotransferase 2B1 proteins in liver and testis of pigs of two breeds: Relationship with adipose tissue androstenone concentration. Journal of Animal Science, 85(11), 2924-2931. https://doi.org/10.2527/jas.2007-0283

An excessive accumulation of androstenone in pig adipose tissue is a major contributor to the phenomenon of boar taint. Androstenone deposition is dependent on the rate of androstenone biosynthesis in testis and androstenone degradation in liver. The... Read More about Expression of 3β-hydroxysteroid dehydrogenase, cytochrome P450-c17, and sulfotransferase 2B1 proteins in liver and testis of pigs of two breeds: Relationship with adipose tissue androstenone concentration.

Relationship between carcass weight, adipose tissue androstenone level and expression of the hepatic 3β-hydroxysteroid dehydrogenase in entire commercial pigs (2007)
Journal Article
Nicolau-Solano, S. I., Wittington, F. M., Wood, J. D., & Doran (nee Udovikova), O. (2007). Relationship between carcass weight, adipose tissue androstenone level and expression of the hepatic 3β-hydroxysteroid dehydrogenase in entire commercial pigs. animal, 1(7), 1053-1059. https://doi.org/10.1017/S1751731107000274

Boar taint is a major meat-quality defect in pigs and is due to excessive accumulation of skatole and androstenone in adipose tissue. The present work investigated the relationship between carcass weight, levels of skatole and androstenone in adipose... Read More about Relationship between carcass weight, adipose tissue androstenone level and expression of the hepatic 3β-hydroxysteroid dehydrogenase in entire commercial pigs.

Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene (2007)
Journal Article
Cue, R. A., Nicolau-Solano, S., McGivan, J. D., Wood, J. D., & Doran, O. (2007). Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene. Journal of Animal Science, 85(3), 571-576. https://doi.org/10.2527/jas.2006-366

The entire sequence of the pig 3β-hydroxysteroid dehydrogenase (3β-HSD) gene has recently become known. This gene is deemed to be important in androstenone metabolism in pig liver, and its defective expression has been shown to be related to androste... Read More about Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene.