All Outputs (75)

Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts (2021)
Presentation / Conference
Richards, L. A., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts. Presented at EGU General Assembly 2021

In a basin-wide survey of the River Ganga and key tributaries, from the Himalayan source to the Bay of Bengal in India, we aim to improve the conceptual understanding of downstream water quality trends along > 2000 km. Here we explore the spatial di... Read More about Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts.

Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin (2021)
Presentation / Conference
Khamis, K., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin. Presented at EGU General Assembly 2021

There is increasing interest in monitoring spatial variability in biogeochemical processes using field deployable sensors. Despite this, rigorous assessments of accuracy and optimal sensor configurations remain limited for such applications. We under... Read More about Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2021)
Presentation / Conference
Fox, B., Thorn, R., Dutta, T., & Reynolds, D. (2021, April). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Presented at EGU General Assembly 2021

With increasing pressures on water resources due to population, industrialization, agriculture, urbanization and climatic changes, improved temporal and spatial understanding of water quality is required. The development of new monitoring parameters,... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

Going off-grid – The decentralised production of point-of-use drinking water (2021)
Digital Artefact
Clayton, G. E., Dutta, T. K., Fox, B. G., Thorn, R. M. S., & Reynolds, D. M. Going off-grid – The decentralised production of point-of-use drinking water. [https://www.waterlinepublication.org.uk/articles/going-off-grid-the-decentralised-production-of-point-of-use-drinking-water/]

Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms (2020)
Conference Proceeding
Clayton, G., Thorn, R., & Reynolds, D. (in press). Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms

Summary of key findings Direct disinfection of established Pseudomonas aeruginosa biofilms by electrochemically activated solutions [ECAS] exhibited significantly greater anti-biofilm activity compared to NaOCl and HOCl at free chlorine concentratio... Read More about Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms.

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics (2019)
Journal Article
Slade, E. A., Thorn, R. M. S., Young, A., & Reynolds, D. M. (2019). An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics. BMC Microbiology, 19(1), Article 310. https://doi.org/10.1186/s12866-019-1682-5

Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the... Read More about An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics.

Toolkit Approach for the Selection of Sustainable Arsenic Remediation Approaches for Rural Communities (2019)
Conference Proceeding
Richards, L. A., Kumari, N., Ghosh, A., Joshi, H., Mukherjee, A., Clayton, G. E., …Polya, D. A. (in press). Toolkit Approach for the Selection of Sustainable Arsenic Remediation Approaches for Rural Communities

Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment (2019)
Journal Article
Clayton, G. E., Thorn, R. M., & Reynolds, D. M. (2019). Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment. Frontiers in Environmental Science, 7, Article 35. https://doi.org/10.3389/fenvs.2019.00035

© 2019 Clayton, Thorn and Reynolds. Point-of-use (POU) drinking water treatment systems provide solutions for communities where centralized facilities are unavailable. Effective POU systems treat and reduce the number of pathogens in POU water suppl... Read More about Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment.

Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system (2018)
Journal Article
Fox, B. G., Thorn, R. M., Anesio, A. M., Cox, T., Attridge, J. W., & Reynolds, D. M. (2019). Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system. Water, 11(1), Article 10. https://doi.org/10.3390/w11010010

© 2018 by the authors. Organic matter (OM) has an essential biogeochemical influence along the hydrological continuum and within aquatic ecosystems. Organic matter derived via microbial processes was investigated within a range of model freshwater sa... Read More about Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system.

CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML (2018)
Journal Article
Anderson, E., Mehta, P., Heywood, J., Rees, B., Bone, H., Robinson, G., …Mayer, L. (2018). CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML. Leukemia Research, 74, 121-129. https://doi.org/10.1016/j.leukres.2018.08.007

© 2018 Elsevier Ltd CPX-351, a liposomal formulation co-encapsulating cytarabine and daunorubicin (DNR) in a synergistic 5:1 M ratio, has shown favourable response in newly diagnosed elderly high-risk AML. This study assessed intracellular ara-CTP le... Read More about CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML.

Visualization of phage genomic data: Comparative genomics and publication-quality diagrams (2018)
Book Chapter
Reynolds, D. M., Turner, D., Sutton, J. M., Reynolds, D. M., Sim, E. M., & Petty, N. K. (2018). Visualization of phage genomic data: Comparative genomics and publication-quality diagrams. In R. Lavigne, A. M. Kropinski, & M. Clokie (Eds.), Bacteriophages. Methods in Molecular Biology (239-260). New York, NY: Springer. https://doi.org/10.1007/978-1-4939-7343-9_18

© 2018, Springer Science+Business Media LLC. The presentation of bacteriophage genomes as diagrams allows the location and organization of features to be communicated in a clear and effective manner. A wide range of software applications are availabl... Read More about Visualization of phage genomic data: Comparative genomics and publication-quality diagrams.

Comparative analysis of 37 Acinetobacter bacteriophages (2017)
Journal Article
Reynolds, D. M., Kropinski, A. M., Turner, D., Ackermann, H. W., Kropinski, A., Lavigne, R., …Reynolds, D. M. (2018). Comparative analysis of 37 Acinetobacter bacteriophages. Viruses, 10(1), 5. https://doi.org/10.3390/v10010005

© 2017 by the authors. Licensee MDPI, Basel, Switzerland. Members of the genus Acinetobacter are ubiquitous in the environment and the multipledrug resistant species A. baumannii is of significant clinical concern. This clinical relevance is currentl... Read More about Comparative analysis of 37 Acinetobacter bacteriophages.

Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS) (2017)
Journal Article
May, J., Robinson, G., Thorn, R., & Reynolds, D. (2017). Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS). Mutagenesis, 32(6), 622-623. https://doi.org/10.1093/mutage/gex033

Electrochemically activated solutions (ECAS) are of interest as potential disinfectants due to high biocidal activity against many microorganisms. They are widely used clinically in some countries (decontamination of surgical instruments and wounds),... Read More about Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS).

Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes (2017)
Journal Article
Clayton, G., Thorn, R., & Reynolds, D. M. (2019). Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes. Journal of Water Process Engineering, 30, Article 100480. https://doi.org/10.1016/j.jwpe.2017.08.018

© 2017 Elsevier Ltd Approximately 800 million people live without clean drinking water. Diarrhoea is responsible for between 1.7 and 2 million deaths each year (primarily children) which are the result of poor drinking water quality and sanitation. T... Read More about Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes.

The in situ bacterial production of fluorescent organic matter; An investigation at a species level (2017)
Journal Article
Fox, B. G., Thorn, R. M. S., Anesio, A. M., & Reynolds, D. M. (2017). The in situ bacterial production of fluorescent organic matter; An investigation at a species level. Water Research, 125, 350-359. https://doi.org/10.1016/j.watres.2017.08.040

© 2017 The Authors Aquatic dissolved organic matter (DOM) plays an essential role in biogeochemical cycling and transport of organic matter throughout the hydrological continuum. To characterise microbially-derived organic matter (OM) from common env... Read More about The in situ bacterial production of fluorescent organic matter; An investigation at a species level.

Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions (2017)
Journal Article
Thorn, R., Pendred, J., & Reynolds, D. M. (2017). Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions. Food Microbiology, 68, 41-50. https://doi.org/10.1016/j.fm.2017.06.018

© 2017 The main aim of this study was to assess the antimicrobial efficacy of electrochemically activated fog (ECAF) for reducing the microbial bio-burden on artificially inoculated fresh produce held under cooled (cucumber and vine tomatoes) or cold... Read More about Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions.

In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry (2017)
Journal Article
Slade, E. A., Thorn, R. M., Lovering, A. M., Young, A., & Reynolds, D. M. (2017). In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry. Journal of Applied Microbiology, 123(1), 233-245. https://doi.org/10.1111/jam.13473

© 2017 The Society for Applied Microbiology Aims: To determine if bacterial species responsible for clinically relevant wound infection produce specific volatile profiles that would allow their speciation. Methods and Results: Selected ion flow tube-... Read More about In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry.

Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB-AbaS-Loki (2017)
Journal Article
Turner, D., Wand, M. E., Briers, Y., Lavigne, R., Sutton, J. M., & Reynolds, D. M. (2017). Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB-AbaS-Loki. PLoS ONE, 12(2), e0172303. https://doi.org/10.1371/journal.pone.0172303

© 2017 Turner et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred... Read More about Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB-AbaS-Loki.

Dissolved organic carbon transformations and microbial community response to variations in recharge waters in a shallow carbonate aquifer (2016)
Journal Article
Cooper, K. J., Whitaker, F. F., Anesio, A. M., Naish, M., Reynolds, D. M., & Evans, E. L. (2016). Dissolved organic carbon transformations and microbial community response to variations in recharge waters in a shallow carbonate aquifer. Biogeochemistry, 129(1-2), 215-234. https://doi.org/10.1007/s10533-016-0226-4

© 2016, The Author(s). In carbonate aquifers, dissolved organic carbon from the surface drives heterotrophic metabolism, generating CO2 in the subsurface. Although this has been a proposed mechanism for enhanced dissolution at the water table, respir... Read More about Dissolved organic carbon transformations and microbial community response to variations in recharge waters in a shallow carbonate aquifer.

Fluorescence spectroscopy for wastewater monitoring: A review (2016)
Journal Article
Carstea, E. M., Carstea, E., Bridgeman, J., Baker, A., & Reynolds, D. M. (2016). Fluorescence spectroscopy for wastewater monitoring: A review. Water Research, 95, 205-219. https://doi.org/10.1016/j.watres.2016.03.021

© 2016. Wastewater quality is usually assessed using physical, chemical and microbiological tests, which are not suitable for online monitoring, provide unreliable results, or use hazardous chemicals. Hence, there is an urgent need to find a rapid an... Read More about Fluorescence spectroscopy for wastewater monitoring: A review.