Skip to main content

Research Repository

Advanced Search

All Outputs (42)

Investigation of the active biofilm communities on polypropylene filter media in a fixed biofilm reactor for wastewater treatment (2018)
Journal Article
Saroj, D. P., Naz, I., Avignone-Rossa, C., Hodgson, D., Lynch, J., Smith, A., …Sehar, S. (2018). Investigation of the active biofilm communities on polypropylene filter media in a fixed biofilm reactor for wastewater treatment. Journal of Chemical Technology and Biotechnology, 93(11), 3264-3275. https://doi.org/10.1002/jctb.5686

© 2018 Society of Chemical Industry BACKGROUND: This research is focused on the effect of temperature on the growth of active biofilms on polypropylene (PP) filter media in aerobic fixed biofilm reactors (FBR) for wastewater treatment. RESULTS: High-... Read More about Investigation of the active biofilm communities on polypropylene filter media in a fixed biofilm reactor for wastewater treatment.

Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans (2018)
Journal Article
L'Heureux, J. E., Jones, A. M., Vanhatalo, A., Blackwell, J. R., Williams, D. W., Smith, A., …van der Giezen, M. (2018). Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans. Free Radical Biology and Medicine, 124, 21-30. https://doi.org/10.1016/j.freeradbiomed.2018.05.078

© 2018 The Author(s) Imbalances in the oral microbial community have been associated with reduced cardiovascular and metabolic health. A possible mechanism linking the oral microbiota to health is the nitrate (NO3-)-nitrite (NO2-)-nitric oxide (NO) p... Read More about Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans.

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin (2018)
Journal Article
Kindinger, L. M., Brown, R. G., Terzidou, V., Marchesi, J. R., Lee, Y. S., Holmes, E., …MacIntyre, D. A. (2018). Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. BMC Medicine, 16(1), Article 9. https://doi.org/10.1186/s12916-017-0999-x

© 2018 The Author(s). Background: Preterm prelabour rupture of the fetal membranes (PPROM) precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis. As PPROM is strongly associated with ascending vaginal infection, prophyla... Read More about Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin.

Comparison of vaginal microbiota sampling techniques: Cytobrush versus swab (2017)
Journal Article
Mitra, A., MacIntyre, D. A., Mahajan, V., Lee, Y. S., Smith, A., Marchesi, J. R., …Kyrgiou, M. (2017). Comparison of vaginal microbiota sampling techniques: Cytobrush versus swab. Scientific Reports, 7(1), https://doi.org/10.1038/s41598-017-09844-4

© 2017 The Author(s). Evidence suggests the vaginal microbiota (VM) may influence risk of persistent Human Papillomavirus (HPV) infection and cervical carcinogenesis. Established cytology biobanks, typically collected with a cytobrush, constitute a... Read More about Comparison of vaginal microbiota sampling techniques: Cytobrush versus swab.

Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study (2017)
Journal Article
Thursz, M. R., Cobbold, J. F., Atkinson, S., Marchesi, J. R., Smith, A., Wai, S. N., …Umpleby, A. M. (2018). Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study. Hepatology Research, 48(1), 69-77. https://doi.org/10.1111/hepr.12904

© 2017 The Japan Society of Hepatology. Aim: Gut microbial dysbiosis is implicated in the pathogenesis of non-alcoholic steatohepatitis (NASH). We investigated downstream effects of gut microbiota modulation on markers of hepatic inflammation, steato... Read More about Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study.

Endotracheal tubes and fluid aspiration: An in vitro evaluation of new cuff technologies (2017)
Journal Article
Mariyaselvam, M. Z., Marsh, L. L., Bamford, S., Smith, A., Wise, M. P., & Williams, D. W. (2017). Endotracheal tubes and fluid aspiration: An in vitro evaluation of new cuff technologies. BMC Anesthesiology, 17(1), https://doi.org/10.1186/s12871-017-0328-0

© 2017 The Author(s). Background: Aspiration of subglottic secretions past the endotracheal tube (ETT) cuff is a prerequisite for developing ventilator-associated pneumonia (VAP). Subglottic secretion drainage (SSD) ETTs reduce aspiration of subglott... Read More about Endotracheal tubes and fluid aspiration: An in vitro evaluation of new cuff technologies.

Community analysis of dental plaque and endotracheal tube biofilms from mechanically ventilated patients (2017)
Journal Article
Marino, P. J., Wise, M. P., Smith, A., Marchesi, J. R., Riggio, M. P., Lewis, M. A., & Williams, D. W. (2017). Community analysis of dental plaque and endotracheal tube biofilms from mechanically ventilated patients. Journal of Critical Care, 39, 149-155. https://doi.org/10.1016/j.jcrc.2017.02.020

© 2017 Elsevier Inc. Purpose Mechanically ventilated patients are at risk for developing ventilator-associated pneumonia, and it has been reported that dental plaque provides a reservoir of respiratory pathogens that may aspirate to the lungs and end... Read More about Community analysis of dental plaque and endotracheal tube biofilms from mechanically ventilated patients.

The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk (2017)
Journal Article
Lee, Y. S., Kindinger, L. M., Bennett, P. R., Marchesi, J. R., Smith, A., Cacciatore, S., …MacIntyre, D. A. (2017). The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk. Microbiome, 5(1), Article 9802. https://doi.org/10.1186/s40168-016-0223-9

© The Author(s) 2017. Background: Preterm birth is the primary cause of infant death worldwide. A short cervix in the second trimester of pregnancy is a risk factor for preterm birth. In specific patient cohorts, vaginal progesterone reduces this ris... Read More about The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk.

Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage (2016)
Journal Article
McDonald, J. A., Kindinger, L. M., MacIntyre, D. A., Lee, Y. S., Marchesi, J. R., Smith, A., …Bennett, P. R. (2016). Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage. Science Translational Medicine, 8(350), Article 350ra102. https://doi.org/10.1126/scitranslmed.aag1026

Preterm birth, the leading cause of death in children under 5 years, may be caused by inflammation triggered by ascending vaginal infection. About 2 million cervical cerclages are performed annually to prevent preterm birth. The procedure is thought... Read More about Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage.

Microbial profiling of dental plaque from mechanically ventilated patients (2016)
Journal Article
Williams, D. W., Wilson, M. J., Marchesi, J. R., Wise, M. P., Lewis, M. A., Twigg, J. A., …Smith, A. (2016). Microbial profiling of dental plaque from mechanically ventilated patients. Journal of Medical Microbiology, 65(2), 147-159. https://doi.org/10.1099/jmm.0.000212

© 2015 The Authors. Micro-organisms isolated from the oral cavity may translocate to the lower airways during mechanical ventilation (MV) leading to ventilator-associated pneumonia (VAP). Changes within the dental plaque microbiome during MV have bee... Read More about Microbial profiling of dental plaque from mechanically ventilated patients.

Effect of the chemical composition of filter media on the microbial community in wastewater biofilms at different temperatures (2016)
Journal Article
Naz, I., Hodgson, D., Smith, A., Marchesi, J., Ahmed, S., Avignone-Rossa, C., & Saroj, D. P. (2016). Effect of the chemical composition of filter media on the microbial community in wastewater biofilms at different temperatures. RSC Advances, 6(106), 104345-104353. https://doi.org/10.1039/c6ra21040f

© 2016 The Royal Society of Chemistry. This study investigates the microbial community composition in the biofilms grown on two different support media in fixed biofilm reactors for aerobic wastewater treatment, using next generation sequencing (NGS)... Read More about Effect of the chemical composition of filter media on the microbial community in wastewater biofilms at different temperatures.

Segregation of the anodic microbial communities in a microbial fuel cell cascade (2016)
Journal Article
Hodgson, D. M., Smith, A., Dahale, S., Stratford, J. P., Li, J. V., Grüning, A., …Avignone Rossa, C. (2016). Segregation of the anodic microbial communities in a microbial fuel cell cascade. Frontiers in Microbiology, 7(MAY), https://doi.org/10.3389/fmicb.2016.00699

© 2016 Hodgson, Smith, Dahale, Stratford, Li, Grüning, Bushell, Marchesi and Avignone Rossa. Metabolic interactions within microbial communities are essential for the efficient degradation of complex organic compounds, and underpin natural phenomena... Read More about Segregation of the anodic microbial communities in a microbial fuel cell cascade.

Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity (2015)
Journal Article
Holmes, E., Mitra, A., MacIntyre, D. A., Lee, Y. S., Smith, A., Marchesi, J. R., …Kyrgiou, M. (2015). Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity. Scientific Reports, 5(1), https://doi.org/10.1038/srep16865

Persistent infection with oncogenic Human Papillomavirus (HPV) is necessary for cervical carcinogenesis. Although evidence suggests that the vaginal microbiome plays a functional role in the persistence or regression of HPV infections, this has yet t... Read More about Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity.

Rapid detection of emerging pathogens and loss of microbial diversity associated with severe lung disease in cystic fibrosis (2015)
Journal Article
Flight, W. G., Smith, A., Paisey, C., Marchesi, J. R., Bull, M. J., Norville, P. J., …Mahenthiralingam, E. (2015). Rapid detection of emerging pathogens and loss of microbial diversity associated with severe lung disease in cystic fibrosis. Journal of Clinical Microbiology, 53(7), 2022-2029. https://doi.org/10.1128/JCM.00432-15

Copyright © 2015, American Society for Microbiology. All Rights Reserved. Respiratory infection in cystic fibrosis (CF) is polymicrobial, but standard sputum microbiology does not account for the lung microbiome or detect changes in microbial diversi... Read More about Rapid detection of emerging pathogens and loss of microbial diversity associated with severe lung disease in cystic fibrosis.

The vaginal microbiome during pregnancy and the postpartum period in a European population (2015)
Journal Article
MacIntyre, D. A., Chandiramani, M., Lee, Y. S., Kindinger, L., Smith, A., Angelopoulos, N., …Bennett, P. R. (2015). The vaginal microbiome during pregnancy and the postpartum period in a European population. Scientific Reports, 5(1), https://doi.org/10.1038/srep08988

© 2015, Macmillan Publishers Limited. All rights reserved. The composition and structure of the pregnancy vaginal microbiome may influence susceptibility to adverse pregnancy outcomes. Studies on the pregnant vaginal microbiome have largely been limi... Read More about The vaginal microbiome during pregnancy and the postpartum period in a European population.

An analysis of the potential to utilize virtual worlds to enhance edutainment and improve the wellbeing of the ageing population (2013)
Book Chapter
Smith, A., & Chilcott, M. (2013). An analysis of the potential to utilize virtual worlds to enhance edutainment and improve the wellbeing of the ageing population. . Springer Verlag. https://doi.org/10.1007/978-3-642-37042-7_4

The contribution of this paper identifies the importance of developing and designing tailored virtual places which older members of society can utilize easily and safely within this context; with a focused application of addressing social isolation,... Read More about An analysis of the potential to utilize virtual worlds to enhance edutainment and improve the wellbeing of the ageing population.

Ageing well and learning through online immersive participation using a multi-user Web 3D environment (2011)
Conference Proceeding
Chilcott, M., & Smith, A. (2011). Ageing well and learning through online immersive participation using a multi-user Web 3D environment. https://doi.org/10.1109/VS-GAMES.2011.16

The Second Life (SL) multi-user virtual environment offers researcher opportunities to experiment with its rich communication, virtual collaboration, and 3-D content creation integrated tools. The SL synthetic world has already revealed great potenti... Read More about Ageing well and learning through online immersive participation using a multi-user Web 3D environment.