Efficient and scalable generation of human ventral midbrain astrocytes from human-induced pluripotent stem cells
(2021)
Journal Article
Crompton, L. A., McComish, S. F., Stathakos, P., Cordero-Llana, O., Lane, J. D., & Caldwell, M. A. (2021). Efficient and scalable generation of human ventral midbrain astrocytes from human-induced pluripotent stem cells. Journal of Visualized Experiments, Article e62095. https://doi.org/10.3791/62095
In Parkinson's disease, progressive dysfunction and degeneration of dopamine neurons in the ventral midbrain cause life-changing symptoms. Neuronal degeneration has diverse causes in Parkinson's, including non-cell autonomous mechanisms mediated by a... Read More about Efficient and scalable generation of human ventral midbrain astrocytes from human-induced pluripotent stem cells.