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All Outputs (2)

Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line (2017)
Journal Article
Daly, C. S., Flemban, A., Shafei, M., Conway, M. E., Qualtrough, D., & Dean, S. J. (2018). Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line. Oncology Reports, 39(2), 483-490. https://doi.org/10.3892/or.2017.6125

A common feature among pre-malignant lesions is the induction of hypoxia through increased cell propagation and reduced access to blood flow. Hypoxia in breast cancer has been associated with poor patient prognosis, resistance to chemotherapy and inc... Read More about Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line.

Divergent metabolic regulation of autophagy and mTORC1-early events in Alzheimer's disease? (2017)
Journal Article
Harris, M., Shafei, M., & Conway, M. E. (2017). Divergent metabolic regulation of autophagy and mTORC1-early events in Alzheimer's disease?. Frontiers in Aging Neuroscience, 9(JUN), https://doi.org/10.3389/fnagi.2017.00173

© 2017 Shafei, Harris and Conway. Alzheimer's disease (AD) is a progressive disease associated with the production and deposition of amyloid β-peptide (Aβ) aggregates and neurofibrillary tangles, which lead to synaptic and neuronal damage. Reduced au... Read More about Divergent metabolic regulation of autophagy and mTORC1-early events in Alzheimer's disease?.