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Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR) (2016)
Journal Article
Turner, A., Sasse, J., & Varadi, A. (2016). Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR). BMC Medical Genetics, 17, Article 75. https://doi.org/10.1186/s12881-016-0334-y

© 2016 The Author(s). Objectives: Inherited disorders of haemoglobin are the world's most common genetic diseases, resulting in significant morbidity and mortality. The large number of mutations associated with the haemoglobin beta gene (HBB) makes g... Read More about Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR).

Stroke event simulator using virtual reality (2016)
Conference Proceeding
Nicolaou, P., Loizou, M., & Loizides, F. (2016). Stroke event simulator using virtual reality. In 2016 8th International Conference on Games and Virtual Worlds for Serious Applications (VS-Games). https://doi.org/10.1109/VS-GAMES.2016.7590368

This poster presents the initial stages of an investigation of a realistic virtual reality scenario aimed at increasing the compassion people feel for people that have suffered a stroke. A Bespoke Virtual Reality environment was developed using the U... Read More about Stroke event simulator using virtual reality.

Virtual reality simulation training for student nurse education (2016)
Conference Proceeding
Elliman, J., Loizou, M., & Loizides, F. (2016). Virtual reality simulation training for student nurse education. In 2016 8th International Conference on Games and Virtual Worlds for Serious Applications (VS-Games). https://doi.org/10.1109/VS-GAMES.2016.7590377

In this paper, the current developments for Virtual Reality (VR) simulation in the Nursing Education sector is investigated with the design and implementation of a 'serious game' that utilizes the increased immersive user experience of Head-Mounted D... Read More about Virtual reality simulation training for student nurse education.

A cross disciplinary embodiment: Exploring the impacts of embedding science communication principles in a collaborative learning space (2016)
Book Chapter
Weitkamp, E., & Arnold, D. L. (2016). A cross disciplinary embodiment: Exploring the impacts of embedding science communication principles in a collaborative learning space. In M. de Vries, & M. van der Sanden (Eds.), Science and Technology Education and Communication: Seeking Synergy (63-84). Rotterdam: Sense Publishers

This chapter reports on the short term impacts of a workshop involving pupils and suggests ways in which by working together scientists, science communicators and teachers can co-develop engaging and inspirational learning opportunities that place sc... Read More about A cross disciplinary embodiment: Exploring the impacts of embedding science communication principles in a collaborative learning space.

Experimentally comparing the attractiveness of domestic lights to insects: Do LEDs attract fewer insects than conventional light types? (2016)
Journal Article
Wakefield, A., Broyles, M., Stone, E. L., Jones, G., & Harris, S. (2016). Experimentally comparing the attractiveness of domestic lights to insects: Do LEDs attract fewer insects than conventional light types?. Ecology and Evolution, 6(22), 8028-8036. https://doi.org/10.1002/ece3.2527

© 2016 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. LED lighting is predicted to constitute 70% of the outdoor and residential lighting markets by 2020. While the use of LEDs promotes energy and cost savings relative to tr... Read More about Experimentally comparing the attractiveness of domestic lights to insects: Do LEDs attract fewer insects than conventional light types?.

Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa (2016)
Presentation / Conference
Steven, J., Robinson, G., & Nelson, S. (2016, October). Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa

Poster presentation. Introduction Pseudomonas aeruginosa and Staphylococcus aureus are significant pathogens of wounds and the cystic fibrosis lung. There are likely to be complex interactions between the two species, with biofilm co-culture aff... Read More about Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa.

Transforming our world: The 2030 agenda & international decade for people of African descent (2016)
Presentation / Conference
Olaiya, H. B. A. (2016, October). Transforming our world: The 2030 agenda & international decade for people of African descent. Presented at International Development, University of the West of England, Bristol, UK

This research presentation highlights aims, objectives, methodology, focus and scope of the research, etc; and its relevance to Politics and International relations. The presentation was made to undergraduates on the International Development Course,... Read More about Transforming our world: The 2030 agenda & international decade for people of African descent.

An MHD couple stress fluid due to a perforated sheet undergoing linear stretching with heat transfer (2016)
Journal Article
Hill, A. A., Mahabaleshwar, U. S., Sarris, I. E., Hill, A. A., Lorenzini, G., & Pop, I. (2017). An MHD couple stress fluid due to a perforated sheet undergoing linear stretching with heat transfer. International Journal of Heat and Mass Transfer, 105, 157-167. https://doi.org/10.1016/j.ijheatmasstransfer.2016.09.040

© 2016 Elsevier Ltd We investigate an MHD couple stress liquid due to a perforated sheet undergoing linear stretching with radiation. The liquid is initially at rest with its activity is restricted by pulling the two sheet ends with parallel and iden... Read More about An MHD couple stress fluid due to a perforated sheet undergoing linear stretching with heat transfer.

Insulin receptor isoform variations in prostate cancer cells (2016)
Journal Article
Perks, C. M., Zielinska, H. A., Wang, J., Jarrett, C., Frankow, A., Ladomery, M. R., …Holly, J. M. P. (2016). Insulin receptor isoform variations in prostate cancer cells. Frontiers in Endocrinology, 7(SEP), https://doi.org/10.3389/fendo.2016.00132

� 2016 Perks, Zielinska, Wang, Jarrett, Frankow, Ladomery, Bahl, Rhodes, Oxley and Holly. Men who develop prostate cancer (PCa) increasingly have one of the co-morbidities associated with a Western lifestyle that are characterized by hyperinsulinem... Read More about Insulin receptor isoform variations in prostate cancer cells.

Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm ™ ) (2016)
Journal Article
Wills, J. W., Hondow, N., Thomas, A. D., Chapman, K. E., Fish, D., Maffeis, T. G., …Doak, S. H. (2016). Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm ™ ). Particle and Fibre Toxicology, 13, Article 50. https://doi.org/10.1186/s12989-016-0161-5

© 2016 The Author(s). Background: The rapid production and incorporation of engineered nanomaterials into consumer products alongside research suggesting nanomaterials can cause cell death and DNA damage (genotoxicity) makes in vitro assays desirabl... Read More about Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm ™ ).

Measurement of the viscoelastic properties of blood plasma clot formation in response to tissue factor concentration-dependent activation (2016)
Journal Article
Killard, A. J., Lakshmanan, R. S., Efremov, V., O’Donnell, J. S., & Killard, A. (2016). Measurement of the viscoelastic properties of blood plasma clot formation in response to tissue factor concentration-dependent activation. Analytical and Bioanalytical Chemistry, 408(24), 6581-6588. https://doi.org/10.1007/s00216-016-9689-3

© 2016, The Author(s). The coagulation of blood plasma in response to activation with a range of tissue factor (TF) concentrations was studied with a quartz crystal microbalance (QCM), where frequency and half width at half maximum (bandwidth) values... Read More about Measurement of the viscoelastic properties of blood plasma clot formation in response to tissue factor concentration-dependent activation.

Medical performance and the ‘inaccessible’ experience of illness: An exploratory study (2016)
Journal Article
Weitkamp, E., & Mermikides, A. (2016). Medical performance and the ‘inaccessible’ experience of illness: An exploratory study. Medical Humanities, 42(3), 186-193. https://doi.org/10.1136/medhum-2016-010959

© 2016 Medical Humanities. All rights reserved. We report a survey of audience members’ responses (147 questionnaires collected at seven performances) and 10 in-depth interviews (five former patients and two family members, three medical practitioner... Read More about Medical performance and the ‘inaccessible’ experience of illness: An exploratory study.

Chitinase 3-like 1 expression by human (MG63) osteoblasts in response to lysophosphatidic acid and 1,25-dihydroxyvitamin D3 (2016)
Journal Article
Mansell, J. P., Mansell, J., Cooke, M., Read, M., Rudd, H., Shiel, A. I., …Manso, M. (2016). Chitinase 3-like 1 expression by human (MG63) osteoblasts in response to lysophosphatidic acid and 1,25-dihydroxyvitamin D3. Biochimie, 128-129, 193-200. https://doi.org/10.1016/j.biochi.2016.08.011

© 2016 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM) Chitinase 3-like 1, otherwise known as YKL-40, is a secreted glycoprotein purported to have a role in extracellular matrix metabolism. The first mammalian cell ty... Read More about Chitinase 3-like 1 expression by human (MG63) osteoblasts in response to lysophosphatidic acid and 1,25-dihydroxyvitamin D3.

A low frequency persistent reservoir of a genomic island in a pathogen population ensures island survival and improves pathogen fitness in a susceptible host (2016)
Journal Article
Neale, H., Laister, R., Payne, J., Preston, G., Jackson, R., & Arnold, D. L. (2016). A low frequency persistent reservoir of a genomic island in a pathogen population ensures island survival and improves pathogen fitness in a susceptible host. Environmental Microbiology, 18(11), 4144-4152. https://doi.org/10.1111/1462-2920.13482

The co-evolution of bacterial plant pathogens and their hosts is a complex and dynamic process. Host resistance imposes stress on invading pathogens that can lead to changes in the bacterial genome enabling the pathogen to escape host resistance. We... Read More about A low frequency persistent reservoir of a genomic island in a pathogen population ensures island survival and improves pathogen fitness in a susceptible host.

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral (2016)
Journal Article
Adukwu, E. C., Adukwu, E., Bowles, M., Edwards-Jones, V., & Bone, H. (2016). Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral. Applied Microbiology and Biotechnology, 100(22), 9619-9627. https://doi.org/10.1007/s00253-016-7807-y

© 2016, The Author(s). The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility scr... Read More about Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral.

A fully integrated microfluidic device for point of care monitoring of antithrombotics (2016)
Journal Article
Killard, A. J., Harris, L. F., Rainey, P., Lindahl, T. L., & Killard, A. (2016). A fully integrated microfluidic device for point of care monitoring of antithrombotics. Analytical Methods, 8(35), 6500-6505. https://doi.org/10.1039/c6ay01566b

© 2016 The Royal Society of Chemistry. The simplicity and efficiency of point of care diagnostics have revolutionised patient care. Current methods for measuring hypercoagulability often require trained technicians, large blood volumes, and result in... Read More about A fully integrated microfluidic device for point of care monitoring of antithrombotics.

Voltammetric behaviour and determination of clonazepam using a disposable screen-printed sensor and its determination in serum and wine (2016)
Presentation / Conference
Honeychurch, K. C., Brooks, J., & Hart, J. P. (2016, August). Voltammetric behaviour and determination of clonazepam using a disposable screen-printed sensor and its determination in serum and wine. Presented at Electrochem 2016, Leicester, UK

Clonazepam Screen-printed Carbon Electrodes Cyclic Voltammetry Gas chromatography mass spectrometry Adsorptive Stripping Voltammetry Sample Preparation and Analysis Conclusions

Pseudomonas syringae Differentiates into Phenotypically Distinct Subpopulations During Colonization of a Plant Host (2016)
Journal Article
Rufián, J. S., Sánchez-Romero, M. A., López-Márquez, D., Macho, A. P., Mansfield, J. W., Arnold, D. L., …Beuzón, C. R. (2016). Pseudomonas syringae Differentiates into Phenotypically Distinct Subpopulations During Colonization of a Plant Host. Environmental Microbiology, 18(10), 3593-3605. https://doi.org/10.1111/1462-2920.13497

© 2016 Society for Applied Microbiology and John Wiley & Sons Ltd Bacterial microcolonies with heterogeneous sizes are formed during colonization of Phaseolus vulgaris by Pseudomonas syringae. Heterogeneous expression of structural and regulatory c... Read More about Pseudomonas syringae Differentiates into Phenotypically Distinct Subpopulations During Colonization of a Plant Host.