DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis
(2015)
Journal Article
Fahrer, J., Frisch, J., Nagel, G., Kraus, A., Dörsam, B., Thomas, A. D., …Kaina, B. (2015). DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis. Carcinogenesis, 36(10), 1235-1244. https://doi.org/10.1093/carcin/bgv114
© The Author 2015. Published by Oxford University Press. All rights reserved. Epidemiological studies indicate that N-nitroso compounds (NOC) are causally linked to colorectal cancer (CRC). NOC induce DNA alkylations, including O6-methylguanine (O6-M... Read More about DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.