All Outputs (2)

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness (2011)
Journal Article
Sood, A., Salih, S., Roh, D., Lacharme-Lora, L., Parry, M., Hardiman, B., …Case, C. P. (2011). Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness. Nature Nanotechnology, 6(12), 824-833. https://doi.org/10.1038/nnano.2011.188

The use of nanoparticles in medicine is ever increasing, and it is important to understand their targeted and non-targeted effects. We have previously shown that nanoparticles can cause DNA damage to cells cultured below a cellular barrier without cr... Read More about Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.

Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm (2011)
Journal Article
Trichas, G., Joyce, B., Crompton, L. A., Wilkins, V., Clements, M., Tada, M., …Srinivas, S. (2011). Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm. PLoS Biology, 9(2), Article e1001019. https://doi.org/10.1371/journal.pbio.1001019

The anterior visceral endoderm (AVE), a signalling centre within the simple epithelium of the visceral endoderm (VE), is required for anterior-posterior axis specification in the mouse embryo. AVE cells migrate directionally within the VE, thereby pr... Read More about Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm.