A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia
(2010)
Journal Article
Salisbury, V. C., Hill, P. J., Angell, J. E., Ruddock, M. W., Martin, A. D., Alloush, H. M., …Mehta, P. (2010). A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia. Clinical Chemistry, 56(12), 1862-1870. https://doi.org/10.1373/clinchem.2010.145581
BACKGROUND: The nucleoside analog cytarabine (Ara-C [cytosine arabinoside]) is the key agent for treating acute myeloid leukemia (AML); however, up to 30% of patients fail to respond to treatment. Screening of patient blood samples to determine drug... Read More about A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia.