A mitotic role for BRCA1/BARD1 in tumor suppression?
(2006)
Journal Article
Clarke, P. R., & Sanderson, H. S. (2006). A mitotic role for BRCA1/BARD1 in tumor suppression?. Cell, 127(3), 453-455. https://doi.org/10.1016/j.cell.2006.10.020
The tumor-suppressor protein BRCA1 is thought to act by preserving genomic integrity. In this issue of Cell, Joukov et al. (2006) demonstrate that the BRCA1/BARD1 heterodimer participates in mitotic spindle assembly, a process conducted by the GTPase... Read More about A mitotic role for BRCA1/BARD1 in tumor suppression?.