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The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone (2004)
Journal Article
Doran, E., Tambyrajah, W. S., Doran (nee Udovikova), O., Wood, J. D., & McGivan, J. D. (2004). The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone. Archives of Biochemistry and Biophysics, 431(2), 252-260. https://doi.org/10.1016/j.abb.2004.08.016

Functional analysis of the pig cytochrome P4502E1 (CYP2E1) promoter identified two major activating elements. One corresponded to the hepatic nuclear factor 1 (HNF-1) consensus binding sequence at nucleotides -128/-98 and the other was located in the... Read More about The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone.

Characterisation of androstenone metabolism in pig liver microsomes (2004)
Journal Article
Doran (nee Udovikova), O., Whittington, F. M., Wood, J. D., & McGivan, J. D. (2004). Characterisation of androstenone metabolism in pig liver microsomes. Chemico-Biological Interactions, 147(2), 141-149. https://doi.org/10.1016/j.cbi.2003.12.002

Androstenone (5α-androst-16-en-3-one) is a steroid pheromone produced in the testis. Excessive accumulation of androstenone together with skatole (3-methyl-indole) in the adipose tissue of some male pigs leads to "boar taint". In isolated pig hepatoc... Read More about Characterisation of androstenone metabolism in pig liver microsomes.