p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer
(2004)
Journal Article
McCloud, J. M., Sivakumar, R., Greenhough, A., Elder, J., Jones, P. W., Deakin, M., …Hoban, P. R. (2004). p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer. International Journal of Oncology, 25(5), 1447-1452. https://doi.org/10.3892/ijo.25.5.1447
Deregulated tumour expression of p16INK4a has previously been described in association with clinical progression in sporadic colorectal cancer patients (CRC). Furthermore, p16INK4a promoter hypermethylation leading to gene silencing has been shown to... Read More about p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer.