All Outputs (2)

Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)+ ribonucleoprotein (1999)
Journal Article
Hastie, N. D., Ladomery, M. R., Ladomery, M., Slight, J., Mc Ghee, S., & Hastie, N. (1999). Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)+ ribonucleoprotein. Journal of Biological Chemistry, 274(51), 36520-36526. https://doi.org/10.1074/jbc.274.51.36520

The tumor suppressor gene WT1 encodes a zinc finger protein, which consists of four C-terminal C2-H2 zinc fingers of the Kruppel type, and at the N terminus a Q/P-rich trans-regulatory domain, both characteristic of transcription factors. However, re... Read More about Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)+ ribonucleoprotein.

Multiple roles for the Wilms' tumor suppressor, WT1 (1999)
Journal Article
Davies, R., Moore, A., Schedl, A., Bratt, E., Miyahawa, K., Ladomery, M., …Hastie, N. (1999). Multiple roles for the Wilms' tumor suppressor, WT1. Cancer Research, 59, 1747s-1750s

Wilms' tumor is a childhood kidney tumor that is a striking example of the way that cancer may arise through development gone awry. A proportion of these tumors develop as a result of the loss of function mutations in the Wilms' tumor suppressor gene... Read More about Multiple roles for the Wilms' tumor suppressor, WT1.