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All Outputs (4)

IT-assisted comprehensive geriatric assessment for residents in care homes: Quasiexperimental longitudinal study (2024)
Journal Article
Attwood, D., Vafidis, J., Boorer, J., Long, S., Ellis, W., Earley, M., …Hope, S. (2024). IT-assisted comprehensive geriatric assessment for residents in care homes: Quasiexperimental longitudinal study. BMC Geriatrics, 24(1), 269. https://doi.org/10.1186/s12877-024-04824-6

Background Frailty interventions such as Comprehensive Geriatric Assessment (CGA) can provide significant benefits for older adults living with frailty. However, incorporating such proactive interventions into primary care remains a challenge. We dev... Read More about IT-assisted comprehensive geriatric assessment for residents in care homes: Quasiexperimental longitudinal study.

Modeling peptide nucleic acid binding enthalpies using MM-GBSA (2022)
Journal Article
Goodman, J., Attwood, D., Kiely, J., Coladas Mato, P., & Luxton, R. (2022). Modeling peptide nucleic acid binding enthalpies using MM-GBSA. Journal of Physical Chemistry B, 126(46), 9528-9538. https://doi.org/10.1021/acs.jpcb.2c05547

The binding enthalpies of peptide nucleic acid (PNA) homoduplexes were predicted using a molecular mechanics generalized Born surface area approach. Using the nucleic acid nearest-neighbor model, these were decomposed into sequence parameters which c... Read More about Modeling peptide nucleic acid binding enthalpies using MM-GBSA.

A non-contact impedimetric biosensing system for classification of toxins associated with cytotoxicity testing (2020)
Journal Article
Gasser, A., Eveness, J., Kiely, J., Attwood, D., & Luxton, R. (2020). A non-contact impedimetric biosensing system for classification of toxins associated with cytotoxicity testing. Bioelectrochemistry, 133, 107448. https://doi.org/10.1016/j.bioelechem.2019.107448

© 2019 We report on a novel impedance spectroscopy measurement and data analysis technique for cytotoxicity testing. The technique combines non-contact measurement with real-time impedance data analysis based on the toxin dose dependency of the outpu... Read More about A non-contact impedimetric biosensing system for classification of toxins associated with cytotoxicity testing.

The application of detrended fluctuation analysis to assess physical characteristics of the human cell line ECV304 following toxic challenges (2019)
Journal Article
Djawad, Y. A., Attwood, D., Kiely, J., & Luxton, R. (2019). The application of detrended fluctuation analysis to assess physical characteristics of the human cell line ECV304 following toxic challenges. Sensing and Bio-Sensing Research, 23, Article 100269. https://doi.org/10.1016/j.sbsr.2019.100269

© 2019 In this paper we present a non-contact, impedance-based sensor system capable of characterizing the toxic response of cells to three different types of toxin. ECV304 cells were treated with 1 mM Hydrogen peroxide, 5% Dimethyl Sulfoxide, and 10... Read More about The application of detrended fluctuation analysis to assess physical characteristics of the human cell line ECV304 following toxic challenges.