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A systematic review of machine-learning solutions in anaerobic digestion (2023)
Journal Article
Rutland, H., You, J., Liu, H., Bull, L., & Reynolds, D. (2023). A systematic review of machine-learning solutions in anaerobic digestion. Bioengineering, 10(12), Article 1410. https://doi.org/10.3390/bioengineering10121410

The use of machine learning (ML) in anaerobic digestion (AD) is growing in popularity and improves the interpretation of complex system parameters for better operation and optimisation. This systematic literature review aims to explore how ML is curr... Read More about A systematic review of machine-learning solutions in anaerobic digestion.

HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings (2023)
Journal Article
Mehendale, F. V., Mehendale, F., Homyer, K. M., Clayton, G., Reynolds, D. M., Homyer, K., & Reynolds, D. (2023). HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings. Journal of Global Health Reports, 7, Article e2023052. https://doi.org/10.29392/001c.84488

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion... Read More about HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings.

Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp. (2023)
Journal Article
Bhattacharyya, M., Dhar, R., Basu, S., Das, A., Reynolds, D. M., & Dutta, T. K. (2023). Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp. Microbial Cell Factories, 22(1), 82. https://doi.org/10.1186/s12934-023-02096-0

Background: Di(2-ethylhexyl) phthalate (DEHP) is a widely detected plasticizer and a priority pollutant of utmost concern for its adverse impact on humans, wildlife and the environment. To eliminate such toxic burden, biological processes are the mos... Read More about Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp..

The control of waterborne pathogenic bacteria in fresh water using a biologically active filter (2022)
Journal Article
Steven, J. A. C., Thorn, R. M. S., Robinson, G. M., Turner, D., Lee, J. E., & Reynolds, D. M. (2022). The control of waterborne pathogenic bacteria in fresh water using a biologically active filter. npj Clean Water, 5(1), 30. https://doi.org/10.1038/s41545-022-00169-y

The aim of this study was to investigate the control of three species of bacteria commonly associated with biologically contaminated water, using biofiltration. In this study, a laboratory-scale biofilter system was used to investigate the control of... Read More about The control of waterborne pathogenic bacteria in fresh water using a biologically active filter.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2022)
Journal Article
Fox, B., Thorn, R., Dutta, T., Bowes, M., Read, D., & Reynolds, D. (2022). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Science of the Total Environment, 842, 156848. https://doi.org/10.1016/j.scitotenv.2022.156848

The quality and health of many of our vital freshwater systems are poor. To tackle this with ever increasing pressures from anthropogenic and climatic changes, we must improve water quality monitoring and devise and implement more appropriate water q... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model (2022)
Journal Article
Perrin, E. M., Thorn, R. M., Sargeant, S. L., Attridge, J. W., & Reynolds, D. M. (2022). The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model. Frontiers in Microbiology, 13, Article 817976. https://doi.org/10.3389/fmicb.2022.817976

Dissolved organic matter (DOM) is ubiquitous throughout aquatic systems. Fluorescence techniques can be used to characterize the fluorescing proportion of DOM, aquatic fluorescent organic matter (AFOM). AFOM is conventionally named in association wit... Read More about The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model.

Marimo actuated rover systems (2022)
Journal Article
Phillips, N., Draper, T. C., Mayne, R., Reynolds, D. M., & Adamatzky, A. (2022). Marimo actuated rover systems. Journal of Biological Engineering, 16(1), Article 3. https://doi.org/10.1186/s13036-021-00279-0

Background: The potential to directly harness photosynthesis to make actuators, biosensors and bioprocessors has been previously demonstrated in the literature. Herein, this capability has been expanded to more advanced systems — Marimo Actuated Rove... Read More about Marimo actuated rover systems.

The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water (2021)
Journal Article
Clayton, G. E., Thorn, R., & Reynolds, D. (2021). The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water. npj Clean Water, 4(1), Article 48. https://doi.org/10.1038/s41545-021-00139-w

Chlorine solutions are used extensively for the production of biologically safe drinking water. The capability of point-of-use [POU] drinking water treatment systems has gained interest in locations where centralised treatment systems and distributio... Read More about The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water.

Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection (2021)
Journal Article
Slade, E., Thorn, R., Young, A., & Reynolds, D. (2022). Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection. Journal of Applied Microbiology, 132(3), 1558-1572. https://doi.org/10.1111/jam.15313

Aims: The main aim of this study was to investigate the real-time detection of volatile metabolites for the species-level discrimination of pathogens associated with clinically relevant wound infection, when grown in a collagen wound biofilm model. M... Read More about Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection.

Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria (2021)
Journal Article
Fox, B. G., Thorn, R. M. S., & Reynolds, D. M. (2021). Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria. Microorganisms, 9(8), Article 1623. https://doi.org/10.3390/microorganisms9081623

This work investigates the origin and range of fluorescent organic matter (FOM) produced in-situ by environmentally sourced freshwater bacteria. Aquatic FOM is an essential component in global carbon cycling and is generally classified as either auto... Read More about Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria.

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics (2019)
Journal Article
Slade, E. A., Thorn, R. M. S., Young, A., & Reynolds, D. M. (2019). An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics. BMC Microbiology, 19(1), Article 310. https://doi.org/10.1186/s12866-019-1682-5

Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the... Read More about An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics.

Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment (2019)
Journal Article
Clayton, G. E., Thorn, R. M., & Reynolds, D. M. (2019). Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment. Frontiers in Environmental Science, 7, Article 35. https://doi.org/10.3389/fenvs.2019.00035

© 2019 Clayton, Thorn and Reynolds. Point-of-use (POU) drinking water treatment systems provide solutions for communities where centralized facilities are unavailable. Effective POU systems treat and reduce the number of pathogens in POU water suppl... Read More about Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment.

Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system (2018)
Journal Article
Fox, B. G., Thorn, R. M., Anesio, A. M., Cox, T., Attridge, J. W., & Reynolds, D. M. (2019). Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system. Water, 11(1), Article 10. https://doi.org/10.3390/w11010010

© 2018 by the authors. Organic matter (OM) has an essential biogeochemical influence along the hydrological continuum and within aquatic ecosystems. Organic matter derived via microbial processes was investigated within a range of model freshwater sa... Read More about Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system.

CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML (2018)
Journal Article
Anderson, E., Mehta, P., Heywood, J., Rees, B., Bone, H., Robinson, G., …Mayer, L. (2018). CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML. Leukemia Research, 74, 121-129. https://doi.org/10.1016/j.leukres.2018.08.007

© 2018 Elsevier Ltd CPX-351, a liposomal formulation co-encapsulating cytarabine and daunorubicin (DNR) in a synergistic 5:1 M ratio, has shown favourable response in newly diagnosed elderly high-risk AML. This study assessed intracellular ara-CTP le... Read More about CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML.

Comparative analysis of 37 Acinetobacter bacteriophages (2017)
Journal Article
Reynolds, D. M., Kropinski, A. M., Turner, D., Ackermann, H. W., Kropinski, A., Lavigne, R., …Reynolds, D. M. (2018). Comparative analysis of 37 Acinetobacter bacteriophages. Viruses, 10(1), 5. https://doi.org/10.3390/v10010005

© 2017 by the authors. Licensee MDPI, Basel, Switzerland. Members of the genus Acinetobacter are ubiquitous in the environment and the multipledrug resistant species A. baumannii is of significant clinical concern. This clinical relevance is currentl... Read More about Comparative analysis of 37 Acinetobacter bacteriophages.

Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS) (2017)
Journal Article
May, J., Robinson, G., Thorn, R., & Reynolds, D. (2017). Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS). Mutagenesis, 32(6), 622-623. https://doi.org/10.1093/mutage/gex033

Electrochemically activated solutions (ECAS) are of interest as potential disinfectants due to high biocidal activity against many microorganisms. They are widely used clinically in some countries (decontamination of surgical instruments and wounds),... Read More about Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS).

Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes (2017)
Journal Article
Clayton, G., Thorn, R., & Reynolds, D. M. (2019). Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes. Journal of Water Process Engineering, 30, Article 100480. https://doi.org/10.1016/j.jwpe.2017.08.018

© 2017 Elsevier Ltd Approximately 800 million people live without clean drinking water. Diarrhoea is responsible for between 1.7 and 2 million deaths each year (primarily children) which are the result of poor drinking water quality and sanitation. T... Read More about Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes.

The in situ bacterial production of fluorescent organic matter; An investigation at a species level (2017)
Journal Article
Fox, B. G., Thorn, R. M. S., Anesio, A. M., & Reynolds, D. M. (2017). The in situ bacterial production of fluorescent organic matter; An investigation at a species level. Water Research, 125, 350-359. https://doi.org/10.1016/j.watres.2017.08.040

© 2017 The Authors Aquatic dissolved organic matter (DOM) plays an essential role in biogeochemical cycling and transport of organic matter throughout the hydrological continuum. To characterise microbially-derived organic matter (OM) from common env... Read More about The in situ bacterial production of fluorescent organic matter; An investigation at a species level.

Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions (2017)
Journal Article
Thorn, R., Pendred, J., & Reynolds, D. M. (2017). Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions. Food Microbiology, 68, 41-50. https://doi.org/10.1016/j.fm.2017.06.018

© 2017 The main aim of this study was to assess the antimicrobial efficacy of electrochemically activated fog (ECAF) for reducing the microbial bio-burden on artificially inoculated fresh produce held under cooled (cucumber and vine tomatoes) or cold... Read More about Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions.

In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry (2017)
Journal Article
Slade, E. A., Thorn, R. M., Lovering, A. M., Young, A., & Reynolds, D. M. (2017). In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry. Journal of Applied Microbiology, 123(1), 233-245. https://doi.org/10.1111/jam.13473

© 2017 The Society for Applied Microbiology Aims: To determine if bacterial species responsible for clinically relevant wound infection produce specific volatile profiles that would allow their speciation. Methods and Results: Selected ion flow tube-... Read More about In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry.