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β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: A role in the chemopreventive efficacy of aspirin (2012)
Journal Article
Smartt, H. J., Smartt, H., Greenhough, A., Ordóñez-Morán, P., Al-Kharusi, M., Collard, T. J., …Paraskeva, C. (2012). β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: A role in the chemopreventive efficacy of aspirin. British Journal of Cancer, 107(9), 1514-1517. https://doi.org/10.1038/bjc.2012.430

Background: Levels of the pro-tumorigenic prostaglandin PGE 2 are increased in colorectal cancer, previously attributed to increased synthesis through COX-2 upregulation and, more recently, to decreased catabolism. The functionally linked genes 15-pr... Read More about β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: A role in the chemopreventive efficacy of aspirin.

The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO2-induced anxiety (2012)
Journal Article
Diaper, A., Papadopoulos, A., Rich, A. S., Dawson, G. R., Dourish, C. T., Nutt, D. J., & Bailey, J. E. (2012). The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO2-induced anxiety. Human Psychopharmacology: Clinical and Experimental, 27(6), 540-548. https://doi.org/10.1002/hup.2261

Symptoms of anxiety induced by 7.5% CO2 inhalation can be attenuated by acute administration of GABAA receptor anxiolytics such as lorazepam and alprazolam. This study investigated if these effects are dose-related, by comparing a 0.5 mg dose (consid... Read More about The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO2-induced anxiety.

Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic (2012)
Journal Article
Diaper, A., Osman-Hicks, V., Rich, A. S., Craig, K., Dourish, C. T., Dawson, G. R., …Bailey, J. E. (2013). Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic. Journal of Psychopharmacology, 27(2), 135-145. https://doi.org/10.1177/0269881112443742

Previous studies have shown that subjective and objective symptoms of anxiety induced by 7.5% CO2 inhalation can be attenuated by anxiolytics such as lorazepam and, to a lesser extent, paroxetine. Venlafaxine and pregabalin, two other licensed treatm... Read More about Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic.

Reflections on resilience: A psychosocial exploration of the life long impact of having been in care during childhood (2012)
Journal Article
Guest, Y. (2012). Reflections on resilience: A psychosocial exploration of the life long impact of having been in care during childhood. Journal of Social Work Practice, 26(1), 109-124. https://doi.org/10.1080/02650533.2011.601287

Previous studies of adults who grew up in care as children show that they are over-represented in the homeless population, the mental health system, the prison population and substance abuse. However there are other adults who grew up in care who ach... Read More about Reflections on resilience: A psychosocial exploration of the life long impact of having been in care during childhood.

Revealing and quantifying the impaired phonological analysis underpinning impaired comprehension in Wernicke's aphasia (2012)
Journal Article
Robson, H., Keidel, J. L., Lambon Ralph, M. A., & Sage, K. (2012). Revealing and quantifying the impaired phonological analysis underpinning impaired comprehension in Wernicke's aphasia. Neuropsychologia, 50(2), 276-288. https://doi.org/10.1016/j.neuropsychologia.2011.11.022

Wernicke's aphasia is a condition which results in severely disrupted language comprehension following a lesion to the left temporo-parietal region. A phonological analysis deficit has traditionally been held to be at the root of the comprehension im... Read More about Revealing and quantifying the impaired phonological analysis underpinning impaired comprehension in Wernicke's aphasia.