All Outputs (71)

The manufacturing and characterisation of eugenol-enclosed liposomes produced by microfluidic method (2023)
Journal Article
Ghodke, J., Ekonomou, S. I., Weaver, E., Lamprou, D., Doran, O., & Stratakos, A. C. (2023). The manufacturing and characterisation of eugenol-enclosed liposomes produced by microfluidic method. Foods, 12(15), Article 2940. https://doi.org/10.3390/foods12152940

In this study, liposomes enclosing eugenol were prepared using microfluidics. Two lipids—1,2-dimyristoyl-sn-glycero-3-phosphocholine, 18:0 (DSPC) and 2-dimyristoyl-sn-glycero-3-phosphocholine, 14:0 (DMPC)—and microfluidic chips with serpentine and Y-... Read More about The manufacturing and characterisation of eugenol-enclosed liposomes produced by microfluidic method.

Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids (2023)
Journal Article
Smart, A., Crew, A., Doran, O., & Hart, J. (2023). Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids. Journal of Food Composition and Analysis, 122, Article 105488. https://doi.org/10.1016/j.jfca.2023.105488

This paper describes, for the first time, the development of a novel trilinolein biosensor based on the immobilisation of lipase and lipoxygenase (LOX) onto a cobalt phthalocyanine screen-printed carbon electrode (CoPC-SPCE) in conjunction with amper... Read More about Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids.

Development of geraniol-loaded liposomal nanoformulations against salmonella colonization in the pig gut (2022)
Journal Article
Ekonomou, S. I., Thanekar, A., Lamprou, D. A., Weaver, E., Doran, O., & Statakos, A. C. (2022). Development of geraniol-loaded liposomal nanoformulations against salmonella colonization in the pig gut. Journal of Agricultural and Food Chemistry, 70(23), 7004-7014. https://doi.org/10.1021/acs.jafc.2c00910

Salmonella is a global health threat, with pig production being one of the main sources of human salmonellosis. The current study investigated the antivirulence properties of geraniol for inhibiting the in vitro colonization of Salmonella. The minimu... Read More about Development of geraniol-loaded liposomal nanoformulations against salmonella colonization in the pig gut.

Inhibition of corrosion causing Pseudomonas aeruginosa using plasma-activated water (2021)
Journal Article
Asimakopoulou, E., Εkonomou, S. Ι., Papakonstantinou, P., Doran, O., & Stratakos, A. C. (in press). Inhibition of corrosion causing Pseudomonas aeruginosa using plasma-activated water. Journal of Applied Microbiology, https://doi.org/10.1111/jam.15391

Aims: The cost of Microbiologically Influenced Corrosion (MIC) significantly affects a wide range of sectors. This study aims to assess the efficiency of a novel technology based on the use of plasma-activated water (PAW) in inhibiting corrosion caus... Read More about Inhibition of corrosion causing Pseudomonas aeruginosa using plasma-activated water.

The effect of cold atmospheric plasma and linalool nanoemulsions against Escherichia coli O157:H7 and Salmonella on ready-to-eat chicken meat (2021)
Journal Article
González-González, C. R., Labo-Popoola, O., Delgado-Pando, G., Theodoridou, K., Doran, O., & Stratakos, A. C. (2021). The effect of cold atmospheric plasma and linalool nanoemulsions against Escherichia coli O157:H7 and Salmonella on ready-to-eat chicken meat. LWT - Food Science and Technology, 149, Article 111898. https://doi.org/10.1016/j.lwt.2021.111898

In this study, the antimicrobial efficiency of a novel low-voltage piezoelectric direct discharge generated cold plasma (CAP) and linalool-loaded nanoemulsion washing (LW) was assessed against Salmonella and Escherichia coli O157:H7 on ready-to-eat (... Read More about The effect of cold atmospheric plasma and linalool nanoemulsions against Escherichia coli O157:H7 and Salmonella on ready-to-eat chicken meat.

Studies towards the development of a novel, screen-printed carbon-based, biosensor for the measurement of polyunsaturated fatty acids (2020)
Journal Article
Smart, A., Hart, J., Crew, A., & Doran, O. (2020). Studies towards the development of a novel, screen-printed carbon-based, biosensor for the measurement of polyunsaturated fatty acids. Applied Sciences, 10(21), 1-13. https://doi.org/10.3390/app10217779

This paper describes the design, development and characterisation of an electrochemical biosensor for the measurement of linoleic and α-linolenic acid, as representative free polyunsaturated fatty acids (PUFAs), that may be implicated in food safety... Read More about Studies towards the development of a novel, screen-printed carbon-based, biosensor for the measurement of polyunsaturated fatty acids.

Screen-printed carbon based biosensors and their applications in agri-food safety (2020)
Journal Article
Smart, A., Crew, A., Pemberton, R., Hughes, G., Doran, O., & Hart, J. P. (2020). Screen-printed carbon based biosensors and their applications in agri-food safety. Trends in Analytical Chemistry, 127, Article 115898. https://doi.org/10.1016/j.trac.2020.115898

This review focuses on the ways in which screen-printed carbon electrodes have been tailored with different biorecognition elements, including enzymes, antibodies, and aptamers, often with other modifiers, such as mediators and nanoparticles, to prod... Read More about Screen-printed carbon based biosensors and their applications in agri-food safety.

Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method (2019)
Journal Article
Westmacott, K. L., Crew, A. P., Doran, O., & Hart, J. P. (2020). Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method. Biosensors and Bioelectronics, 150, Article 111837. https://doi.org/10.1016/j.bios.2019.111837

© 2019 Elsevier B.V. This is the first report on the fabrication, characterisation and application of an electrochemical (bio)sensor system for the simultaneous measurement of skatole and androstenone. A biosensor for androstenone was fabricated usin... Read More about Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method.

An electrocatalytic screen-printed amperometric sensor for the selective measurement of thiamine (Vitamin B1) in food supplements (2019)
Journal Article
Smart, A., Westmacott, K. L., Crew, A., Doran, O., & Hart, J. P. (2019). An electrocatalytic screen-printed amperometric sensor for the selective measurement of thiamine (Vitamin B1) in food supplements. Biosensors, 9(3), Article 98. https://doi.org/10.3390/bios9030098

An electrocatalytic screen-printed sensor has been investigated for the measurement of the biologically important biomolecule vitamin B1 (thiamine) for the first time in food supplements. Under basic conditions, the vitamin was converted to its elect... Read More about An electrocatalytic screen-printed amperometric sensor for the selective measurement of thiamine (Vitamin B1) in food supplements.

Association of single nucleotide polymorphisms in leptin (LEP) and leptin receptor (LEPR) genes with backfat thickness and daily weight gain in Ukrainian Large White pigs (2018)
Journal Article
Balatsky, V., Oliinychenko, Y., Sarantseva, N., Getya, A., Saienko, A., Vovk, V., & Doran, O. (2018). Association of single nucleotide polymorphisms in leptin (LEP) and leptin receptor (LEPR) genes with backfat thickness and daily weight gain in Ukrainian Large White pigs. Livestock Science, 217, 157-161. https://doi.org/10.1016/j.livsci.2018.09.015

© 2018 Elsevier B.V. Leptin (LEP) and leptin receptor (LEPR) genes play an important role in the regulation of fat deposition and other commercially important traits in pigs and this regulation is known to be breed-specific. The aim of the present st... Read More about Association of single nucleotide polymorphisms in leptin (LEP) and leptin receptor (LEPR) genes with backfat thickness and daily weight gain in Ukrainian Large White pigs.

7-Hydroxylation of warfarin is strongly inhibited by sesamin, but not by episesamin, caffeic and ferulic acids in human hepatic microsomes (2018)
Journal Article
Pilipenko, N., Rasmussen, M. K., Doran, O., & Zamaratskaia, G. (2018). 7-Hydroxylation of warfarin is strongly inhibited by sesamin, but not by episesamin, caffeic and ferulic acids in human hepatic microsomes. Food and Chemical Toxicology, 113, 14-18. https://doi.org/10.1016/j.fct.2018.01.020

© 2018 Elsevier Ltd Warfarin is a commonly used anticoagulant drug and is a derivate of coumarin. Cytochrome P450 2C9 (CYP2C9) plays the key role in transformation of coumarin and thus, influences determination of warfarin dosage. A number of factors... Read More about 7-Hydroxylation of warfarin is strongly inhibited by sesamin, but not by episesamin, caffeic and ferulic acids in human hepatic microsomes.

A novel electroanalytical approach to the measurement of B vitamins in food supplements based on screen-printed carbon sensors (2017)
Journal Article
Westmacott, K. L., Crew, A. P., Doran, O., & Hart, J. P. (2018). A novel electroanalytical approach to the measurement of B vitamins in food supplements based on screen-printed carbon sensors. Talanta, 181, 13-18. https://doi.org/10.1016/j.talanta.2017.12.074

© 2017 Elsevier B.V. This paper describes the development of a novel electrochemical assay for the measurement of water-soluble vitamins in food and pharmaceutical products. The optimum conditions for the determination of vitamin B1 (thiamine), B2 (r... Read More about A novel electroanalytical approach to the measurement of B vitamins in food supplements based on screen-printed carbon sensors.

The reduction of starch in finishing diets supplemented with oil does not prevent the accumulation of trans-10 18:1 in lamb meat (2017)
Journal Article
Prates, J. A., Costa, M., Alves, S. P., Francisco, A., Almeida, J., Alfaia, C. M., …Bessa, R. J. (2017). The reduction of starch in finishing diets supplemented with oil does not prevent the accumulation of trans-10 18:1 in lamb meat. Journal of Animal Science, 95(8), 3745-3761. https://doi.org/10.2527/jas.2017.1578

© 2017 American Society of Animal Science. All rights reserved. The experiment was conducted to test the hypothesis that the replacement of cereal with low-starch feed ingredients in lambs’ finishing diets supplemented with oils could prevent the acc... Read More about The reduction of starch in finishing diets supplemented with oil does not prevent the accumulation of trans-10 18:1 in lamb meat.

Polymorphisms of the porcine cathepsins, growth hormone-releasing hormone and leptin receptor genes and their association with meat quality traits in Ukrainian Large White breed (2016)
Journal Article
Balatsky, V., Bankovska, I., Pena, R. N., Saienko, A., Buslyk, T., Korinnyi, S., & Doran, O. (2016). Polymorphisms of the porcine cathepsins, growth hormone-releasing hormone and leptin receptor genes and their association with meat quality traits in Ukrainian Large White breed. Molecular Biology Reports, 43(6), 517-526. https://doi.org/10.1007/s11033-016-3977-z

© 2016, The Author(s). Cathepsins, growth hormone-releasing hormone (GHRH) and leptin receptor (LEPR) genes have been receiving increasing attention as potential markers for meat quality and pig performance traits. This study investigated the allele... Read More about Polymorphisms of the porcine cathepsins, growth hormone-releasing hormone and leptin receptor genes and their association with meat quality traits in Ukrainian Large White breed.

Influence of betaine and arginine supplementation of reduced protein diets on fatty acid composition and gene expression in the muscle and subcutaneous adipose tissue of cross-bred pigs (2016)
Journal Article
Madeira, M. S., Rolo, E. A., Alfaia, C. M., Pires, V. R., Luxton, R., Doran, O., …Prates, J. A. (2016). Influence of betaine and arginine supplementation of reduced protein diets on fatty acid composition and gene expression in the muscle and subcutaneous adipose tissue of cross-bred pigs. British Journal of Nutrition, 115(6), 937-950. https://doi.org/10.1017/S0007114515005218

© The Authors 2016. The isolated or combined effects of betaine and arginine supplementation of reduced protein diets (RPD) on fat content, fatty acid composition and mRNA levels of genes controlling lipid metabolism in pig m. longissimus lumborum an... Read More about Influence of betaine and arginine supplementation of reduced protein diets on fatty acid composition and gene expression in the muscle and subcutaneous adipose tissue of cross-bred pigs.

Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process (2015)
Journal Article
Chen, G., Bai, Y., Ren, L., Zhu, D., Li, Y., Fang, M., …Doran, O. (2015). Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process. PLoS ONE, 10(1), Article e113194. https://doi.org/10.1371/journal.pone.0113194

© 2015 Chen et al. Steroids metabolism plays an important role in mammals and contributes to quality of pig meat. The main objective of this study was to identify metabolites of androstenone, 17β-estradiol and dihydrotestosterone using primary cultur... Read More about Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process.

Combined effects of dietary arginine, leucine and protein levels on fatty acid composition and gene expression in the muscle and subcutaneous adipose tissue of crossbred pigs (2014)
Journal Article
Madeira, M. S., Pires, V. M., Alfaia, C. M., Luxton, R., Doran, O., Bessa, R. J., & Prates, J. A. (2014). Combined effects of dietary arginine, leucine and protein levels on fatty acid composition and gene expression in the muscle and subcutaneous adipose tissue of crossbred pigs. British Journal of Nutrition, 111(9), 1521-1535. https://doi.org/10.1017/S0007114513004029

The cumulative effects of dietary arginine, leucine and protein levels on fat content, fatty acid composition and mRNA levels of genes controlling lipid metabolism in pig longissimus lumborum muscle and subcutaneous adipose tissue (SAT) were investig... Read More about Combined effects of dietary arginine, leucine and protein levels on fatty acid composition and gene expression in the muscle and subcutaneous adipose tissue of crossbred pigs.

Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs (2013)
Journal Article
Marriott, D. T., Chevillon, P., Spencer-Phillips, P. T., & Doran, O. (2013). Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs. Journal of Food Science, 78(8), C1130-C1135. https://doi.org/10.1111/1750-3841.12191

This study investigated the role of lipogenic enzyme expression in breed-specific fat deposition in pigs. Objectives: (i) determine effect of breed on the relative abundance of the key lipogenic enzymes stearoyl-CoA desaturase (SCD), delta-6 desatura... Read More about Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs.

Differential effects of reduced protein diets on fatty acid composition and gene expression in muscle and subcutaneous adipose tissue of Alentejana purebred and Large White ×â Landrace ×â Pietrain crossbred pigs (2013)
Journal Article
Prates, J. A., Pires, V. M., Bessa, R. J., Madeira, M. S., Pires, V., Alfaia, C. M., …Prates, J. (2013). Differential effects of reduced protein diets on fatty acid composition and gene expression in muscle and subcutaneous adipose tissue of Alentejana purebred and Large White ×â Landrace ×â Pietrain crossbred pigs. British Journal of Nutrition, 110(02), 216-229. https://doi.org/10.1017/S0007114512004916

The present study assessed the effect of pig genotype (fatty v. lean) and dietary protein and lysine (Lys) levels (normal v. reduced) on intramuscular fat (IMF) content, subcutaneous adipose tissue (SAT) deposition, fatty acid composition and mRNA le... Read More about Differential effects of reduced protein diets on fatty acid composition and gene expression in muscle and subcutaneous adipose tissue of Alentejana purebred and Large White ×â Landrace ×â Pietrain crossbred pigs.

Trpm8 agonists modulate contraction of the pig urinary bladder (2013)
Journal Article
Parsons, B. A., Drake, M. J., Vahabi, B., Parsons, B. A., Doran, O., Rhodes, A., …Drake, M. (2013). Trpm8 agonists modulate contraction of the pig urinary bladder. Canadian Journal of Physiology and Pharmacology, 91(7), 503-509. https://doi.org/10.1139/cjpp-2012-0406

The transient receptor potential melastin-8 (TRPM8) channel is activated by the "cooling" compounds menthol and icilin. Pathophysiologically, it is implicated in the overactive bladder and bladder cooling reflex, but the activity of TRPM8 in normal b... Read More about Trpm8 agonists modulate contraction of the pig urinary bladder.