Modeling and simulation of inverse agonism dynamics
(2010)
Book Chapter
Bridge, L. (2010). Modeling and simulation of inverse agonism dynamics. In Constitutive Activity in Receptors and Other Proteins, Part B (559-582). Elsevier. https://doi.org/10.1016/B978-0-12-381296-4.00029-4
With the recent discovery and increased recognition of constitutive activity of G-protein coupled receptors (GPCRs) and inverse agonists have come a number of important questions. The signaling mechanisms underlying inverse agonist effects on constit... Read More about Modeling and simulation of inverse agonism dynamics.