Mitochondria and cell death
(2000)
Journal Article
Doran, E., Halestrap, A. P., Doran (nee Udovikova), O., Gillespie, J. P., & O'Toole, A. (2000). Mitochondria and cell death. Biochemical Society Transactions, 28(2), 170-177. https://doi.org/10.1042/bst0280170
Mitochondria play a central role in both apoptosis and necrosis through the opening of the mitochondrial permeability transition pore (MPTP). This is thought to be formed through a Ca2+-triggered conformational change of the adenine nucleotide transl... Read More about Mitochondria and cell death.