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Forensic science in Ghana: A review (2019)
Journal Article
Amankwaa, A. O., Nsiah Amoako, E., Mensah Bonsu, D. O., & Banyeh, M. (2019). Forensic science in Ghana: A review. Forensic Science International, 1, 151-160. https://doi.org/10.1016/j.fsisyn.2019.07.008

The use of forensic science continues to grow across the world. In Ghana, major advancements took off in 2011, including the introduction of modern DNA profiling and the establishment of an automated fingerprint identification system. These developme... Read More about Forensic science in Ghana: A review.

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics (2019)
Journal Article
Slade, E. A., Thorn, R. M. S., Young, A., & Reynolds, D. M. (2019). An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics. BMC Microbiology, 19(1), Article 310. https://doi.org/10.1186/s12866-019-1682-5

Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the... Read More about An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics.

Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis (2019)
Journal Article
Akpiri, R. U., Hodges, N. J., & Konya, R. S. (2020). Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis. Journal of Marine Science, 2(1), https://doi.org/10.30564/jms.v2i1.1070

Aluminium is the most abundant element in the earth crust, and has no known biological function. However, it is an established neurotoxicant in its trivalent oxidation state, with exposure resulting in neurodegenerative diseases like Parkinson’s dise... Read More about Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis.

Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease (2019)
Journal Article
May, J., Gynn, L., Anderson, E., & Robinson, G. (2019). Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease. Mutagenesis, 34(5/6), e5. https://doi.org/10.1093/mutage/gez025

Resistance to therapy remains one of the greatest challenges in the management of the blood and bone marrow (BM) disorder, acute myeloid leukaemia (AML). This study aimed to investigate how leukaemic and BM stromal cells contribute to altered chemo-s... Read More about Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease.

The Campylobacter jejuni type VI secretion system enhances the oxidative stress response and host colonization (2019)
Journal Article
Liaw, J., Hong, G., Davies, C., Elmi, A., Sima, F., Stratakos, A., …Dorrell, N. (2019). The Campylobacter jejuni type VI secretion system enhances the oxidative stress response and host colonization. Frontiers in Microbiology, 10, Article 2864. https://doi.org/10.3389/fmicb.2019.02864

The role of the Type VI secretion system (T6SS) in Campylobacter jejuni is poorly understood despite an increasing prevalence of the T6SS in recent C. jejuni isolates in humans and chickens. The T6SS is a contractile secretion machinery capable of de... Read More about The Campylobacter jejuni type VI secretion system enhances the oxidative stress response and host colonization.

Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection (2019)
Journal Article
Barnett, J. M., Monnier, B. M., Tyler, S., West, D., Ballantine-Dykes, H., Regan, E., …Luxton, R. (2020). Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection. Sensing and Bio-Sensing Research, 27, 100315. https://doi.org/10.1016/j.sbsr.2019.100315

© 2019 The resonant coil magnetometer quantifies paramagnetic particles (PMPs) and has been used to develop magneto-immunoassays in a range of formats. The advantage of magneto-immunoassays is that they are relatively inexpensive, portable, easy to p... Read More about Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection.

Density functional theory transition-state modeling for the prediction of Ames mutagenicity in 1,4 Michael acceptors (2019)
Journal Article
Townsend, P. A., & Grayson, M. N. (2019). Density functional theory transition-state modeling for the prediction of Ames mutagenicity in 1,4 Michael acceptors. Journal of Chemical Information and Modeling, 59(12), 5099-5103. https://doi.org/10.1021/acs.jcim.9b00966

Assessing the safety of new chemicals, without introducing the need for animal testing, is a task of great importance. The Ames test, a widely used bioassay to assess mutagenicity, can be an expensive, wasteful process with animal-derived reagents. E... Read More about Density functional theory transition-state modeling for the prediction of Ames mutagenicity in 1,4 Michael acceptors.

Effects of a modified tai chi program on older people with mild dementia: A randomized controlled trial (2019)
Journal Article
Huang, N., Li, W., Rong, X., Champ, M., Wei, L., Li, M., …Lyu, J. (2019). Effects of a modified tai chi program on older people with mild dementia: A randomized controlled trial. Journal of Alzheimer's Disease, 72(3), 947-956. https://doi.org/10.3233/JAD-190487

© 2019-IOS Press and the authors. All rights reserved. Background: Tai Chi exercise is a non-pharmacological therapy that has received increased attention in recent years. A Tai Chi program has been specifically modified for older people with cogniti... Read More about Effects of a modified tai chi program on older people with mild dementia: A randomized controlled trial.

Science Hunters: Teaching science concepts in schools using Minecraft (2019)
Journal Article
Hobbs, L., Stevens, C., Hartley, J., Ashby, M., Jackson, B., Bowden, L., …Bentley, S. (2019). Science Hunters: Teaching science concepts in schools using Minecraft. Action Research and Innovation in Science Education, 2(2), 13-21

Background Science Hunters is an outreach project based at Lancaster University, UK. It uses the computer game Minecraft, alongside interactive discussion and hands-on demonstrations, to engage children with scientific research topics and science l... Read More about Science Hunters: Teaching science concepts in schools using Minecraft.

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). (2019)
Journal Article
Gynn, L. E., Anderson, E., Robinson, G. M., Wexler, S. A., Upstill-Goddard, G., Cox, C., …Morgan, R. G. (2019). Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). Blood, 134(Supplement 1), 2492. https://doi.org/10.1182/blood-2019-122891

Mesenchymal stromal cells (MSC) are known to protect leukemic cells from drug-induced toxicity within the bone marrow (BM) niche, however, less is known about leukemic impact on supportive MSC. The nucleoside-analogue, cytarabine (Ara-C), is a front-... Read More about Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)..

Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method (2019)
Journal Article
Westmacott, K. L., Crew, A. P., Doran, O., & Hart, J. P. (2020). Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method. Biosensors and Bioelectronics, 150, Article 111837. https://doi.org/10.1016/j.bios.2019.111837

© 2019 Elsevier B.V. This is the first report on the fabrication, characterisation and application of an electrochemical (bio)sensor system for the simultaneous measurement of skatole and androstenone. A biosensor for androstenone was fabricated usin... Read More about Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method.

Review of electroanalytical-based approaches for the determination of benzodiazepines (2019)
Journal Article
Honeychurch, K. C. (2019). Review of electroanalytical-based approaches for the determination of benzodiazepines. Biosensors, 9(4), Article 130. https://doi.org/10.3390/bios9040130

The benzodiazepine class of drugs are characterised by a readily electrochemically reducible azomethine group. A number are also substituted by other electrochemically active nitro, N-oxide, and carbonyl groups, making them readily accessible to elec... Read More about Review of electroanalytical-based approaches for the determination of benzodiazepines.

Bird's nest ferns promote resource sharing by centipedes (2019)
Journal Article
Phillips, J., Chung, A. Y. C., Edgecombe, G. D., & Ellwood, F. (2020). Bird's nest ferns promote resource sharing by centipedes. Biotropica, 52(2), 335-344. https://doi.org/10.1111/btp.12713

Bird's nest ferns (Asplenium spp.) support large numbers of invertebrates, including centipedes. As top invertebrate predators, centipedes drive ecosystem function, for example, by regulating decomposer populations, but we know little of their ecolog... Read More about Bird's nest ferns promote resource sharing by centipedes.

Pseudomonas daroniae sp. nov. and Pseudomonas dryadis sp. nov., isolated from pedunculate oak affected by acute oak decline in the UK (2019)
Journal Article
Bueno-Gonzalez, V., Brady, C., Denman, S., Plummer, S., Allainguillaume, J., & Arnold, D. (2019). Pseudomonas daroniae sp. nov. and Pseudomonas dryadis sp. nov., isolated from pedunculate oak affected by acute oak decline in the UK. International Journal of Systematic and Evolutionary Microbiology, 69(11), 3368-3376. https://doi.org/10.1099/ijsem.0.003615

Twenty-two cream-coloured bacterial strains were isolated from oak trees affected by acute oak decline (AOD) in Southern England. Isolates were Gram-negative, motile, slightly curved rods, aerobic, non-spore-forming, catalase positive and oxidase pos... Read More about Pseudomonas daroniae sp. nov. and Pseudomonas dryadis sp. nov., isolated from pedunculate oak affected by acute oak decline in the UK.

Soil microbial biomass increases along elevational gradients in the tropics and subtropics but not elsewhere (2019)
Journal Article
He, X., Hou, E., Veen, G. F., Ellwood, M. D. F., Dijkstra, P., Sui, X., …Chu, C. (2020). Soil microbial biomass increases along elevational gradients in the tropics and subtropics but not elsewhere. Global Ecology and Biogeography, 29(2), 345-354. https://doi.org/10.1111/geb.13017

Aim: Our aim is to use elevational gradients to quantify the relationship between temperature and ecosystem functioning. Ecosystem functions such as decomposition, nutrient cycling and carbon storage are linked with the amount of microbial biomass in... Read More about Soil microbial biomass increases along elevational gradients in the tropics and subtropics but not elsewhere.

Managing the column equilibration time in hydrophilic interaction chromatography (2019)
Journal Article
McCalley, D. V. (2020). Managing the column equilibration time in hydrophilic interaction chromatography. Journal of Chromatography A, 1612, Article 460655. https://doi.org/10.1016/j.chroma.2019.460655

For a wide variety of hydrophilic interaction chromatography stationary phases, a repeatable partial equilibration was demonstrated in gradient elution after purging with as little as 12 column volumes of mobile phase. Relative standard deviations of... Read More about Managing the column equilibration time in hydrophilic interaction chromatography.

A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust (2019)
Journal Article
Henderson, J., Ciesielczuk, H., Nelson, S., Wilks, M., & Cummins, M. (2020). A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust. Journal of Hospital Infection, 104(1), 12-19. https://doi.org/10.1016/j.jhin.2019.10.012

Summary Background There has been an increase in the number of carbapenemase-producing organisms documented across the UK over the past 10 years. From these, the ‘big five’ carbapenemases (KPC, OXA-48, IMP, VIM, and NDM) are the most common types r... Read More about A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust.

What role can Athena SWAN play in gender equality and science communication? (2019)
Journal Article
Wilkinson, C. (2019). What role can Athena SWAN play in gender equality and science communication?. JCOM: Journal of Science Communication, 18(4), Article C06. https://doi.org/10.22323/2.18040306

This essay discusses how gender-focused culture change initiatives developed for science (like Athena SWAN) might offer models for science communication. Such initiatives can seek to mobilise change amongst university departments and practices, but t... Read More about What role can Athena SWAN play in gender equality and science communication?.