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All Outputs (454)

Influence of viscosity, particle size and particle concentration of suspensions on oral grittiness and acceptability in young adults (2010)
Presentation / Conference
Bowles, A., Al-Haddad, I., Ernest, T., Clapham, D., & Tuleu, C. (2010, November). Influence of viscosity, particle size and particle concentration of suspensions on oral grittiness and acceptability in young adults. Poster presented at International Pharmaceutical Federation World Congress/Annual Meeting American Association of Pharmaceutical Scientists, New Orleans, USA

Application of Multiparticulates for Children’s Medicines (2010)
Presentation / Conference
Bowles, A. (2010, October). Application of Multiparticulates for Children’s Medicines. Presented at 2nd Workshop on Multiparticulate Dosage Forms and Controlled Release Formulations, Binzen (Germany)

Specific aspects of gastro-intestinal transit in children for drug delivery design (2010)
Journal Article
Bowles, A., Keane, J., Ernest, T., Clapham, D., & Tuleu, C. (2010). Specific aspects of gastro-intestinal transit in children for drug delivery design. International Journal of Pharmaceutics, 395(1-2), 37-43. https://doi.org/10.1016/j.ijpharm.2010.04.048

This mini-review discusses relevant aspects of gastro-intestinal transit in different ages of paediatric patients with an attempt to highlight factors which should be considered in oral dosage form design, in particular multi-particulate dosage forms... Read More about Specific aspects of gastro-intestinal transit in children for drug delivery design.

Abducting both arms improves stability during breast radiotherapy: The Bi Arm study in breast (2009)
Journal Article
Goldsworthy, S., Tremlett, J., Chalmers, A., & Simcock, R. (2009). Abducting both arms improves stability during breast radiotherapy: The Bi Arm study in breast. Radiotherapy and Oncology, 92, S419

Background: A randomised study to investigate whether bilateral arm abduction is superior to unilateral abduction with respect to stability using shifts on treatment as the main outcome measure.Material and Methods: 50 consecutive female patients wer... Read More about Abducting both arms improves stability during breast radiotherapy: The Bi Arm study in breast.

Topographic indications of emerging keratoconus in teenage New Zealanders (2007)
Journal Article
Boyce, N. K., Gamble, G. D., Owens, H., Bjornholdt, M. C., & Keung, L. (2007). Topographic indications of emerging keratoconus in teenage New Zealanders. Cornea, 26(3), 312-318. https://doi.org/10.1097/ICO.0b013e31802f8d87

PURPOSE: To screen a population of teenagers for emerging topographic signs of keratoconus (KC), with particular reference to ethnicity. METHODS: Corneal topography, visual acuity, and an environmental risk factor analysis were included in a screenin... Read More about Topographic indications of emerging keratoconus in teenage New Zealanders.

A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers (2007)
Journal Article
Bailey, J. E., Kendrick, A., Diaper, A., Potokar, J. P., & Nutt, D. J. (2007). A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers. Journal of Psychopharmacology, 21(1), 42-49. https://doi.org/10.1177/0269881106063889

The inhalation of 7.5% carbon dioxide (CO2) in healthy subjects produces an increase in blood pressure and heart rate, and increased feelings of anxiety, fear and tension (Bailey et al. 2005). As this state is similar to that of general anxiety rathe... Read More about A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers.

The Nepal longitudinal study: Biometric characteristics of developing eyes (2006)
Journal Article
Frith, M. J., Kinnear, R. F., Stewart, A. W., Garner, L. F., & Owens, H. (2006). The Nepal longitudinal study: Biometric characteristics of developing eyes. Optometry and Vision Science, 83(5), 274-280. https://doi.org/10.1097/01.opx.0000215251.27409.16

PURPOSE. To identify differences in potential biometric markers for predicting refractive error in school children. METHODS. Biometric data on 895 Tibetan children, aged 6 to 18 years, residing in Katmandu, Nepal, were collected biennially from 1992... Read More about The Nepal longitudinal study: Biometric characteristics of developing eyes.

Sleep disturbance and its management in older adults (2005)
Book Chapter
Diaper, A., & Hindmarch, I. (2005). Sleep disturbance and its management in older adults. In R. Bullock, & S. Curran (Eds.), Practical Old Age Psychopharmacology: A Multi-Professional Approach. Radcliffe Publishing Ltd

Tailoring mental illness drug treatments specifically for elderly people has been a neglected area. This book brings together findings from recent multi-disciplinary research and the practical aspects of old age psychiatry. By taking into account the... Read More about Sleep disturbance and its management in older adults.

A double-blind, placebo-controlled investigation of the effects of two doses of a valerian preparation on the sleep, cognitive and psychomotor function of sleep-disturbed older adults (2004)
Journal Article
Diaper, A., & Hindmarch, I. (2004). A double-blind, placebo-controlled investigation of the effects of two doses of a valerian preparation on the sleep, cognitive and psychomotor function of sleep-disturbed older adults. Phytotherapy Research, 18(10), 831-836. https://doi.org/10.1002/ptr.1574

One of the most popular herbal remedies for the alleviation of sleep problems is valerian. However, research into valerian is sparse, and studies differ greatly with respect to design, measures, and preparations used. This clinical study used standar... Read More about A double-blind, placebo-controlled investigation of the effects of two doses of a valerian preparation on the sleep, cognitive and psychomotor function of sleep-disturbed older adults.

The relationship between the sagitta of the anterior corneal surface and refractive error of the eye (2004)
Journal Article
Garner, L. F., & Owens, H. (2004). The relationship between the sagitta of the anterior corneal surface and refractive error of the eye. Optometry and Vision Science, 81(8), 636-639. https://doi.org/10.1097/01.opx.0000141798.41340.8b

Changes in the sagitta of the anterior corneal surface associated with a change in the corneal radius of curvature have been used to calculate the change in refractive error of the eye in two areas: the ablation depth for laser surgery, and the chang... Read More about The relationship between the sagitta of the anterior corneal surface and refractive error of the eye.

Posterior corneal changes with orthokeratology (2004)
Journal Article
Owens, H., Garner, L. F., Craig, J. P., & Gamble, G. (2004). Posterior corneal changes with orthokeratology. Optometry and Vision Science, 81(6), 421-426. https://doi.org/10.1097/01.opx.0000135097.99877.5d

Purpose. To investigate changes in corneal thickness and the radius of curvature of the posterior corneal surface after orthokeratology (OK) rigid lens wear. Methods. Nineteen young myopic subjects wore reverse-geometry OK lenses (BE/ABE, Ultravision... Read More about Posterior corneal changes with orthokeratology.