All Outputs (46)

Human mitochondrial branched chain aminotransferase isozyme: Structural role of the CXXC center in catalysis (2006)
Journal Article
Conway, M., Islam, M. M., Yennawar, N. H., Islam, M. M., Conway, M. E., Wallin, R., & Hutson, S. M. (2006). Human mitochondrial branched chain aminotransferase isozyme: Structural role of the CXXC center in catalysis. Journal of Biological Chemistry, 281(51), 39660-39671. https://doi.org/10.1074/jbc.M607552200

Mammalian branched chain aminotransferases (BCATs) have a unique CXXC center. Kinetic and structural studies of three CXXC center mutants (C315A, C318A, and C315A/C318A) of human mitochondrial (hBCATm) isozyme and the oxidized hBCATm enzyme (hBCATm-O... Read More about Human mitochondrial branched chain aminotransferase isozyme: Structural role of the CXXC center in catalysis.

Spontaneous gene flow from rapeseed (Brassica napus) to wild Brassica oleracea (2006)
Journal Article
Wilkinson, M. J., Allender, C. J., Ford, C. S., Allainguillaume, J., Grilli-Chantler, P., & Cuccato, G. (2006). Spontaneous gene flow from rapeseed (Brassica napus) to wild Brassica oleracea. Proceedings of the Royal Society B: Biological Sciences, 273(1605), 3111-3115. https://doi.org/10.1098/rspb.2006.3686

Research on the environmental risks of gene flow from genetically modified (GM) crops to wild relatives has traditionally emphasized recipients yielding most hybrids. For GM rapeseed (Brassica napus), interest has centred on the 'frequently hybridizi... Read More about Spontaneous gene flow from rapeseed (Brassica napus) to wild Brassica oleracea.

Regulation of smooth muscle cell proliferation by β-catenin/T-cell factor signaling involves modulation of cyclin D1 and p21 expression (2006)
Journal Article
Quasnichka, H., Slater, S. C., Beeching, C. A., Boehm, M., Sala-Newby, G. B., & George, S. J. (2006). Regulation of smooth muscle cell proliferation by β-catenin/T-cell factor signaling involves modulation of cyclin D1 and p21 expression. Circulation Research, 99(12), 1329-1337. https://doi.org/10.1161/01.RES.0000253533.65446.33

We previously observed that stimulation of vascular smooth muscle cell (VSMC) proliferation with growth factors is associated with dismantling of cadherin junctions and nuclear translocation of β-catenin. In this study we demonstrate directly that gr... Read More about Regulation of smooth muscle cell proliferation by β-catenin/T-cell factor signaling involves modulation of cyclin D1 and p21 expression.

Some effects of nitrogen nutrition on caesium uptake and translocation by species in the Poaceae, Asteraceae and Caryophyllidae (2006)
Journal Article
Willey, N., & Tang, S. (2006). Some effects of nitrogen nutrition on caesium uptake and translocation by species in the Poaceae, Asteraceae and Caryophyllidae. Environmental and Experimental Botany, 58(1-3), 114-122. https://doi.org/10.1016/j.envexpbot.2005.07.001

There is current interest in managing and manipulating 137Cs transfer from soil to plants. We hypothesized that N source might affect Cs uptake by plants and report experiments that confirm this. Uptake experiments using hydroponics with a variety of... Read More about Some effects of nitrogen nutrition on caesium uptake and translocation by species in the Poaceae, Asteraceae and Caryophyllidae.

Presence of WT1 in nuclear messenger RNP particles in the human acute myeloid leukemia cell lines HL60 and K562 (2006)
Journal Article
Morrison, A. A., & Ladomery, M. (2006). Presence of WT1 in nuclear messenger RNP particles in the human acute myeloid leukemia cell lines HL60 and K562. Cancer Letters, 244(1), 136-141. https://doi.org/10.1016/j.canlet.2005.12.018

The WT1 gene is a key player in acute myeloid leukaemia, in which it is frequently over-expressed. WT1 encodes a multifunctional zinc finger protein transcription factor, which also binds mRNA. Thus increasing evidence suggests that WT1 works both at... Read More about Presence of WT1 in nuclear messenger RNP particles in the human acute myeloid leukemia cell lines HL60 and K562.

Post-harvest spoilage of wheat grains: Malodour formation and the infection process (2006)
Book Chapter
Spencer-Phillips, P. T., Wallington, A., Kockenberger, W., Gunson, H., & Ratcliffe, N. M. (2006). Post-harvest spoilage of wheat grains: Malodour formation and the infection process. In M. Bailey, A. Lilley, T. Timms-Wilson, & P. T. Spencer-Phillips (Eds.), Microbial Ecology of Aerial Plant Surfaces (287-303). Wallingford: CAB International

Linear and non-linear stability thresholds for thermal convection in a box (2006)
Journal Article
Hill, A. A., & Straughan, B. (2006). Linear and non-linear stability thresholds for thermal convection in a box. Mathematical Methods in the Applied Sciences, 29(17), 2123-2132. https://doi.org/10.1002/mma.770

We analyse the problem of finding instability thresholds and global non-linear stability bounds for thermal convection in a linearly viscous fluid in a finite box. The vertical walls are maintained at different temperatures which gives rise to a non-... Read More about Linear and non-linear stability thresholds for thermal convection in a box.

Seasonal variations in decomposition processes in a valley-bottom riparian peatland (2006)
Journal Article
Bonnett, S. A., Ostle, N., & Freeman, C. (2006). Seasonal variations in decomposition processes in a valley-bottom riparian peatland. Science of the Total Environment, 370(2-3), 561-573. https://doi.org/10.1016/j.scitotenv.2006.08.032

A year-long field survey was carried out at a valley-bottom riparian peatland site in North Wales, UK from January 2002 to December 2002 to examine the seasonal variation of decomposition processes and dissolved organic carbon (DOC) concentrations. P... Read More about Seasonal variations in decomposition processes in a valley-bottom riparian peatland.

WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo (2006)
Journal Article
Markus, M. A., Heinrich, B., Raitskin, O., Adams, D. J., Mangs, H., Goy, C., …Morris, B. J. (2006). WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Experimental Cell Research, 312(17), 3379-3388. https://doi.org/10.1016/j.yexcr.2006.07.008

Wilm's tumor protein 1 (WT1), a protein implicated in various cancers and developmental disorders, consists of two major isoforms: WT1(-KTS), a transcription factor, and WT1(+KTS), a post-transcriptional regulator that binds to RNA and can interact w... Read More about WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo.

The Wilms tumour suppressor protein WT1 (+KTS isoform) binds alpha-actinin 1 mRNA via its zinc-finger domain (2006)
Journal Article
Morrison, A. A., Venables, J. P., Dellaire, G., & Ladomery, M. (2006). The Wilms tumour suppressor protein WT1 (+KTS isoform) binds alpha-actinin 1 mRNA via its zinc-finger domain. Biochemistry and Cell Biology, 84(5), 789-798. https://doi.org/10.1139/O06-065

Mutations in WT1 are associated with developmental syndromes that affect the urogenital system and neoplasms, including Wilms tumour, acute myeloid leukemia, and breast and prostate cancers. The WT1 protein belongs to the early growth response family... Read More about The Wilms tumour suppressor protein WT1 (+KTS isoform) binds alpha-actinin 1 mRNA via its zinc-finger domain.

Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk? (2006)
Journal Article
McInnis, S. M., Desikan, R., Hancock, J. T., & Hiscock, S. J. (2006). Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk?. New Phytologist, 172(2), 221-228. https://doi.org/10.1111/j.1469-8137.2006.01875.x

• Angiosperm stigmas exhibit high levels of peroxidase activity when receptive to pollen. To explore possible function(s) of this peroxidase activity we investigated amounts of reactive oxygen species (ROS), particularly hydrogen peroxide, in stigmas... Read More about Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk?.

An analysis of intertaxa differences in sulfur concentration in angiosperms (2006)
Journal Article
Willey, N., & Wilkins, J. (2006). An analysis of intertaxa differences in sulfur concentration in angiosperms. Journal of Plant Nutrition and Soil Science, 169(5), 717-727. https://doi.org/10.1002/jpln.200520590

Understanding the behavior of sulfur (S) in the soil-plant system is important for crop production, for predicting the movement of the radioisotope 35S in the environment, and for investigating the role of S in plant metabolism of xenobiotics. A data... Read More about An analysis of intertaxa differences in sulfur concentration in angiosperms.

The reversibility of constraints on size and fecundity in the parasitic nematode Strongyloides ratti (2006)
Journal Article
Viney, M. E., Steer, M. D., & Wilkes, C. P. (2006). The reversibility of constraints on size and fecundity in the parasitic nematode Strongyloides ratti. Parasitology, 133(4), 477-483. https://doi.org/10.1017/S003118200600062X

The size and fecundity of parasitic nematodes are constrained by the host immune response. For the parasitic nematode of rats, Strongyloides ratti, parasitic females infecting immunized rats are smaller and less fecu1nd than those infecting naïve rat... Read More about The reversibility of constraints on size and fecundity in the parasitic nematode Strongyloides ratti.

Relationship between the expression of hepatic but not testicular 3β-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue (2006)
Journal Article
Wood, J. D., Whittington, F. M., McGivan, J. D., Nicolau-Solano, S. I., Nieuwhof, G. J., & Doran (nee Udovikova), O. (2006). Relationship between the expression of hepatic but not testicular 3β-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue. Journal of Animal Science, 84(10), 2809-2817. https://doi.org/10.2527/jas.2005-595

This study investigated the relationship between expression of hepatic and testicular 3/3-hydroxysteroid dehydrogenase (3/3-HSD) and accumulation of androstenone in adipose tissue because of its relation to boar taint. The experiments were performed... Read More about Relationship between the expression of hepatic but not testicular 3β-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue.

A phylogenetic effect on strontium concentrations in angiosperms (2006)
Journal Article
Willey, N., & Fawcett, K. (2006). A phylogenetic effect on strontium concentrations in angiosperms. Environmental and Experimental Botany, 57(3), 258-269. https://doi.org/10.1016/j.envexpbot.2005.06.005

A Residual Maximum Likelihood (REML) procedure was used to compile Sr concentrations in 103 plant species from experiments with Sr concentrations in 66 plant species from the literature. There were 14 species in common between experiments and the lit... Read More about A phylogenetic effect on strontium concentrations in angiosperms.

N-cadherin and b-catenin signalling regulates vascular smooth muscle cell proliferation and cell cycle genes (2006)
Journal Article
Quasnichka, H. L., Sala-Newby, G. B., & George, S. J. (2006). N-cadherin and b-catenin signalling regulates vascular smooth muscle cell proliferation and cell cycle genes. Vascular Pharmacology, 45(3), 194. https://doi.org/10.1016/j.vph.2006.08.052

Vascular smooth muscle cell (VSMC) proliferation is a key event in the pathogenesis of vascular diseases. Dismantling of cadherin junctions and translocation of b-catenin to the cytoplasm occurs in proliferating VSMCs. To determine whether N-cadherin... Read More about N-cadherin and b-catenin signalling regulates vascular smooth muscle cell proliferation and cell cycle genes.

Science communication: Local air quality management consultation in the UK (2006)
Presentation / Conference
Dorfman, P., Beattie, C., Burnet, F., Gibbs, D., Longhurst, J., Weitkamp, E., & Leksmono, N. (2006, September). Science communication: Local air quality management consultation in the UK. Presented at 15th IUAPPA Conference on Air Pollution and Environmental Health. From Science to Action, Lille, France

Evidence for declining levels of heavy-metals in the Severn Estuary and Bristol Channel, U.K. and their spatial distribution in sediments (2006)
Journal Article
Duquesne, S., Newton, L. C., Giusti, L., Marriott, S. B., Stärk, H. J., & Bird, D. J. (2006). Evidence for declining levels of heavy-metals in the Severn Estuary and Bristol Channel, U.K. and their spatial distribution in sediments. Environmental Pollution, 143(2), 187-196. https://doi.org/10.1016/j.envpol.2005.12.002

Levels of heavy-metals (Cd, Cu, Cr, Ni, Pb and Zn) in suspended particulate and in surface and subsurface sediments were determined at seven locations in the Severn Estuary and Bristol Channel. Sediment metal concentrations were highest at sites clos... Read More about Evidence for declining levels of heavy-metals in the Severn Estuary and Bristol Channel, U.K. and their spatial distribution in sediments.

Arthropod abundance, canopy structure, and microclimate in a Bornean lowland tropical rain forest (2006)
Journal Article
Dial, R. J., Ellwood, M. D. F., Turner, E. C., & Foster, W. A. (2006). Arthropod abundance, canopy structure, and microclimate in a Bornean lowland tropical rain forest. Biotropica, 38(5), 643-652. https://doi.org/10.1111/j.1744-7429.2006.00181.x

This study applies a novel, vertically stratified fogging protocol to document arthropod abundance, density, and biomass across a vertical gradient in a primary, lowland dipterocarp forest canopy in Borneo. We fogged arthropods at 5 m vertical interv... Read More about Arthropod abundance, canopy structure, and microclimate in a Bornean lowland tropical rain forest.

Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis (2006)
Journal Article
Desikan, R., Last, K., Harrett-Williams, R., Tagliavia, C., Harter, K., Hooley, R., …Neill, S. (2006). Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis. Plant Journal, 47(6), 907-916. https://doi.org/10.1111/j.1365-313X.2006.02842.x

Ethylene is a plant hormone that regulates many aspects of growth and development. Despite the well-known association between ethylene and stress signalling, its effects on stomatal movements are largely unexplored. Here, genetic and physiological da... Read More about Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis.